KEGG   PATHWAY: ecoa00630
Entry
ecoa00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Escherichia coli APEC O78 (APEC)
Class
Metabolism; Carbohydrate metabolism
Pathway map
ecoa00630  Glyoxylate and dicarboxylate metabolism
ecoa00630

Module
ecoa_M00012  Glyoxylate cycle [PATH:ecoa00630]
ecoa_M00621  Glycine cleavage system [PATH:ecoa00630]
Other DBs
GO: 0046487 0043648
Organism
Escherichia coli APEC O78 (APEC) [GN:ecoa]
Gene
APECO78_00820  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
APECO78_01260  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
APECO78_00815  malate synthase [KO:K01638] [EC:2.3.3.9]
APECO78_18635  malate synthase G [KO:K01638] [EC:2.3.3.9]
APECO78_19995  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
APECO78_07125  type II citrate synthase [KO:K01647] [EC:2.3.3.1]
APECO78_07350  hydratase [KO:K01681] [EC:4.2.1.3]
APECO78_10250  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
APECO78_04030  aconitate hydratase AcnB [KO:K01682] [EC:4.2.1.3 4.2.1.99]
APECO78_14955  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
APECO78_17830  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
APECO78_18295  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
APECO78_18655  glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
APECO78_18650  glcE; glycolate oxidase FAD binding subunit [KO:K11472] [EC:1.1.99.14]
APECO78_18645  glcF; glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
APECO78_12490  katE; hydroperoxidase II [KO:K03781] [EC:1.11.1.6]
APECO78_09135  2-ketoacid reductase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
APECO78_21575  2-ketoaldonate reductase/glyoxylate reductase B [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
APECO78_20715  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
APECO78_00090  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
APECO78_16485  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
APECO78_18230  glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
APECO78_18240  glycine cleavage system aminomethyltransferase T [KO:K00605] [EC:2.1.2.10]
APECO78_04020  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
APECO78_18235  glycine cleavage system protein H [KO:K02437]
APECO78_06030  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
APECO78_06035  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
APECO78_19460  tartronate semialdehyde reductase [KO:K00042] [EC:1.1.1.60]
APECO78_06040  tartronate semialdehyde reductase [KO:K00042] [EC:1.1.1.60]
APECO78_06065  glycerate kinase [KO:K00865] [EC:2.7.1.165]
APECO78_19455  glycerate kinase I [KO:K00865] [EC:2.7.1.165]
APECO78_10790  aldehyde dehydrogenase A [KO:K07248] [EC:1.2.1.22 1.2.1.21]
APECO78_17615  L-1,2-propanediol oxidoreductase [KO:K00048] [EC:1.1.1.77]
APECO78_19115  tartrate dehydratase subunit alpha [KO:K03779] [EC:4.2.1.32]
APECO78_19120  L-tartrate dehydratase beta subunit [KO:K03780] [EC:4.2.1.32]
APECO78_12800  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
APECO78_13065  keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
APECO78_00220  formate dehydrogenase-O major subunit [KO:K00123] [EC:1.17.1.9]
APECO78_00225  formate dehydrogenase-O major subunit [KO:K00123] [EC:1.17.1.9]
APECO78_00215  formate dehydrogenase-O, iron-sulfur subunit [KO:K00124]
APECO78_00210  formate dehydrogenase-O subunit gamma [KO:K00127]
APECO78_10030  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
APECO78_15620  oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
ecoa00010  Glycolysis / Gluconeogenesis
ecoa00020  Citrate cycle (TCA cycle)
ecoa00030  Pentose phosphate pathway
ecoa00053  Ascorbate and aldarate metabolism
ecoa00071  Fatty acid degradation
ecoa00230  Purine metabolism
ecoa00250  Alanine, aspartate and glutamate metabolism
ecoa00260  Glycine, serine and threonine metabolism
ecoa00620  Pyruvate metabolism
ecoa00710  Carbon fixation by Calvin cycle
ecoa00750  Vitamin B6 metabolism
ecoa00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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