KEGG   PATHWAY: ecv00630
Entry
ecv00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Escherichia coli APEC O1 (APEC)
Class
Metabolism; Carbohydrate metabolism
Pathway map
ecv00630  Glyoxylate and dicarboxylate metabolism
ecv00630

Module
ecv_M00012  Glyoxylate cycle [PATH:ecv00630]
ecv_M00621  Glycine cleavage system [PATH:ecv00630]
Other DBs
GO: 0046487 0043648
Organism
Escherichia coli APEC O1 (APEC) [GN:ecv]
Gene
APECO1_118  ycdW; putative dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
APECO1_1358  gltA; citrate synthase [KO:K01647] [EC:2.3.3.1]
APECO1_1501  glxK; glycerate kinase II [KO:K00865] [EC:2.7.1.165]
APECO1_1505  ybbQ; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
APECO1_1506  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
APECO1_1507  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
APECO1_1656  prpC; 2-methylcitrate synthase [KO:K01659] [EC:2.3.3.5]
APECO1_1867  acnB; aconitate hydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
APECO1_1869  lpd; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
APECO1_2095  gclA; putative glycoxylate carboligase GclA [KO:K01608] [EC:4.1.1.47]
APECO1_2096  gclR; putative regulatory protein GclR [KO:K01816] [EC:5.3.1.22]
APECO1_2097  ghbD; putative 3-hydroxyisobutyrate dehydrogenase GhbD [KO:K00042] [EC:1.1.1.60]
APECO1_2098  gclK; putative glycerate kinase GclK [KO:K00865] [EC:2.7.1.165]
APECO1_2386  acs; acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
APECO1_2408  [KO:K00382] [EC:1.8.1.4]
APECO1_2461  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
APECO1_2462  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
APECO1_2571  fdoG; formate dehydrogenase-O, large subunit [KO:K00123] [EC:1.17.1.9]
APECO1_25712  fdoG; formate dehydrogenase-O, large subunit [KO:K00123] [EC:1.17.1.9]
APECO1_2572  fdoH; formate dehydrogenase-O, Fe-S subunit [KO:K00124]
APECO1_2573  fdoI; formate dehydrogenase-O, cytochrome b556 subunit [KO:K00127]
APECO1_2592  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
APECO1_2895  tkrA; 2-ketoaldonate reductase/glyoxylate reductase B [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
APECO1_3078  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
APECO1_3208  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
APECO1_3302  yhaE; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
APECO1_3303  garK; glycerate kinase I [KO:K00865] [EC:2.7.1.165]
APECO1_3352  ttdB; L(+)-tartrate dehydratase [KO:K03780] [EC:4.2.1.32]
APECO1_3353  ttdA; tartrate dehydratase [KO:K03779] [EC:4.2.1.32]
APECO1_3448  glcD; glycolate oxidase subunit D [KO:K00104] [EC:1.1.99.14]
APECO1_3449  glcF; glycolate oxidase iron-sulfur subunit [KO:K11472] [EC:1.1.99.14]
APECO1_3451  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
APECO1_346  purU; formyltetrahydrofolate hydrolase [KO:K01433] [EC:3.5.1.10]
APECO1_3613  [KO:K01847] [EC:5.4.99.2]
APECO1_3623  gcvT; putative aminomethyltransferase of glycine cleavage system [KO:K00605] [EC:2.1.2.10]
APECO1_3624  gcvH; glycine cleavage system protein H [KO:K02437]
APECO1_3625  gcvP; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
APECO1_3662  yqeF; putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
APECO1_3732  fucO; lactaldehyde reductase [KO:K00048] [EC:1.1.1.77]
APECO1_3980  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
APECO1_4162  yfdW; formyl-coenzyme A transferase [KO:K07749] [EC:2.8.3.16]
APECO1_4163  [KO:K01577] [EC:4.1.1.8]
APECO1_4335  atoB; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
APECO1_436  acnA; aconitate hydratase 1 [KO:K27802]
APECO1_566  aldA; aldehyde dehydrogenase A [KO:K07248] [EC:1.2.1.22 1.2.1.21]
APECO1_801  katE; catalase HPII [KO:K03781] [EC:1.11.1.6]
APECO1_900  eda; 2-keto-3-deoxygluconate 6-phosphate aldolase/2-keto-4-hydroxyglutarate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00049  L-Aspartate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C05840  Iminoaspartate
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C19838  D-erythro-3-Hydroxyaspartate
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
ecv00010  Glycolysis / Gluconeogenesis
ecv00020  Citrate cycle (TCA cycle)
ecv00030  Pentose phosphate pathway
ecv00053  Ascorbate and aldarate metabolism
ecv00071  Fatty acid degradation
ecv00230  Purine metabolism
ecv00250  Alanine, aspartate and glutamate metabolism
ecv00260  Glycine, serine and threonine metabolism
ecv00270  Cysteine and methionine metabolism
ecv00620  Pyruvate metabolism
ecv00710  Carbon fixation by Calvin cycle
ecv00750  Vitamin B6 metabolism
ecv00910  Nitrogen metabolism
KO pathway
ko00630   

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