KEGG   PATHWAY: efl00230
Entry
efl00230                    Pathway                                
Name
Purine metabolism - Enterococcus faecalis 62
Class
Metabolism; Nucleotide metabolism
Pathway map
efl00230  Purine metabolism
efl00230

Module
efl_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:efl00230]
efl_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:efl00230]
efl_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:efl00230]
efl_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:efl00230]
efl_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:efl00230]
Other DBs
GO: 0006163 0042278
Organism
Enterococcus faecalis 62 [GN:efl]
Gene
EF62_2855  ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
EF62_0559  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
EF62_2643  phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
EF62_2435  prs_2; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
EF62_0234  prs_1; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
EF62_2155  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
EF62_2151  purD; Phosphoribosylglycinamide synthetase [KO:K01945] [EC:6.3.4.13]
EF62_2153  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
EF62_2156  purL; phosphoribosylformylglycinamidine synthase II [KO:K23269] [EC:6.3.5.3]
EF62_2158  purS; phosphoribosylformylglycinamidine synthase, PurS protein [KO:K23264] [EC:6.3.5.3]
EF62_2157  purQ; phosphoribosylformylglycinamidine synthase I [KO:K23265] [EC:6.3.5.3 3.5.1.2]
EF62_2154  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
EF62_2551  phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
EF62_2160  purK; phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
EF62_2161  purE; phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
EF62_2159  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
EF62_2550  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
EF62_2152  purH; purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
EF62_2065  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
EF62_0560  deoD-1; purine nucleoside phosphorylase I, inosine and guanosine-specific family protein [KO:K03783] [EC:2.4.2.1]
EF62_0561  deoD-2; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
EF62_0632  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
EF62_0353  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
EF62_1473  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
EF62_0319  Ham1 family protein [KO:K01519] [EC:3.6.1.66]
EF62_2553  xpt; xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
EF62_0539  guaA; Glutamineamidotransferase [KO:K01951] [EC:6.3.5.2]
EF62_2647  guaC; guanosine monophosphate reductase [KO:K00364] [EC:1.7.1.7]
EF62_2649  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
EF62_2763  guanylate kinase [KO:K00942] [EC:2.7.4.8]
EF62_0197  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
EF62_0793  nrdE; ribonucleoside-diphosphate reductase, alpha subunit [KO:K00525] [EC:1.17.4.1]
EF62_0792  nrdF; ribonucleoside-diphosphate reductase, beta subunit [KO:K00526] [EC:1.17.4.1]
EF62_2906  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
EF62_2321  dgt; deoxyguanosinetriphosphate triphosphohydrolase, family protein [KO:K01129] [EC:3.1.5.1]
EF62_2335  GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
EF62_2830  RelA/SpoT domain protein [KO:K07816] [EC:2.7.6.5]
EF62_0405  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
EF62_0543  adD; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
EF62_1667  amidohydrolase family protein [KO:K01486] [EC:3.5.4.2]
EF62_0009  calcineurin-like phosphoesterase family protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
EF62_0240  calcineurin-like phosphoesterase family protein [KO:K09769] [EC:3.1.4.16]
EF62_0598  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
EF62_1984  calcineurin-like phosphoesterase family protein [KO:K03651] [EC:3.1.4.53]
EF62_0083  allB; allantoinase [KO:K01466] [EC:3.5.2.5]
EF62_0082  allC; allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
EF62_0079  aminotransferase class-V family protein [KO:K00839] [EC:2.6.1.112]
EF62_0081  cupin domain protein [KO:K14977] [EC:3.5.3.26]
EF62_0721  allD; ureidoglycolate dehydrogenase [KO:K00073] [EC:1.1.1.350]
EF62_2745  arcC_3; carbamate kinase [KO:K00926] [EC:2.7.2.2]
EF62_0719  arcC_2; carbamate kinase [KO:K00926] [EC:2.7.2.2]
EF62_0491  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
EF62_1121  agcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
efl00030  Pentose phosphate pathway
efl00220  Arginine biosynthesis
efl00250  Alanine, aspartate and glutamate metabolism
efl00260  Glycine, serine and threonine metabolism
efl00630  Glyoxylate and dicarboxylate metabolism
efl00730  Thiamine metabolism
efl00740  Riboflavin metabolism
efl00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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