KEGG   PATHWAY: elc00630
Entry
elc00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Escherichia coli clone D i14
Class
Metabolism; Carbohydrate metabolism
Pathway map
elc00630  Glyoxylate and dicarboxylate metabolism
elc00630

Module
elc_M00012  Glyoxylate cycle [PATH:elc00630]
elc_M00621  Glycine cleavage system [PATH:elc00630]
Other DBs
GO: 0046487 0043648
Organism
Escherichia coli clone D i14 [GN:elc]
Gene
i14_4562  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
i14_4648  acs; acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
i14_3396  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
i14_4561  aceB; malate synthase [KO:K01638] [EC:2.3.3.9]
i14_3674  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
i14_0767  gltA; type II citrate synthase [KO:K01647] [EC:2.3.3.1]
i14_1575  acnA; aconitate hydratase [KO:K01681] [EC:4.2.1.3]
i14_0815  ybhJ; hypothetical protein [KO:K01681] [EC:4.2.1.3]
i14_0134  acnB; bifunctional aconitate hydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
i14_2565  atoB; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
i14_3160  yqeF; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
i14_3219  hypothetical protein [KO:K01847] [EC:5.4.99.2]
i14_3400  glcD; glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
i14_3399  glcE; glycolate oxidase FAD binding subunit [KO:K11472] [EC:1.1.99.14]
i14_3398  pir; glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
i14_1951  katE; hydroperoxidase II [KO:K03781] [EC:1.11.1.6]
i14_1181  ycdW; putative 2-hydroxyacid dehydrogenase ycdW [KO:K12972] [EC:1.1.1.79 1.1.1.81]
i14_4039  yiaE; 2-hydroxyacid dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
i14_3827  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
i14_4412  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
i14_2868  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
i14_3203  gcvP; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
i14_3205  gcvT; glycine cleavage system aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
i14_0132  lpdA; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
i14_4620  putative 2-oxoglutarate dehydrogenase [KO:K00382] [EC:1.8.1.4]
i14_3204  gcvH; glycine cleavage system protein H [KO:K02437]
i14_0598  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
i14_0599  gip; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
i14_0600  ybbQ; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
i14_3569  garR; tartronate semialdehyde reductase [KO:K00042] [EC:1.1.1.60]
i14_0604  ybbZ; glycerate kinase II [KO:K00865] [EC:2.7.1.165]
i14_3568  yhaD; glycerate kinase I [KO:K00865] [EC:2.7.1.165]
i14_1666  aldA; aldehyde dehydrogenase A [KO:K07248] [EC:1.2.1.22 1.2.1.21]
i14_3091  fucO; L-1,2-propanediol oxidoreductase [KO:K00048] [EC:1.1.1.77]
i14_3507  ttdA; tartrate dehydratase subunit alpha [KO:K03779] [EC:4.2.1.32]
i14_3508  ttdB; L(+)-tartrate dehydratase subunit beta [KO:K03780] [EC:4.2.1.32]
i14_2079  eda; keto-hydroxyglutarate-aldolase/2-keto-4-hydroxyglutarate aldolase decarboxylase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
i14_4438  fdoH; formate dehydrogenase-O beta subunit [KO:K00124]
i14_4437  fdoI; formate dehydrogenase-O subunit gamma [KO:K00127]
i14_1527  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
i14_2707  putative oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
i14_2708  yfdW; formyl-coenzyme A transferase [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
elc00010  Glycolysis / Gluconeogenesis
elc00020  Citrate cycle (TCA cycle)
elc00030  Pentose phosphate pathway
elc00053  Ascorbate and aldarate metabolism
elc00071  Fatty acid degradation
elc00230  Purine metabolism
elc00250  Alanine, aspartate and glutamate metabolism
elc00260  Glycine, serine and threonine metabolism
elc00620  Pyruvate metabolism
elc00710  Carbon fixation by Calvin cycle
elc00750  Vitamin B6 metabolism
elc00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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