KEGG   PATHWAY: elo00630
Entry
elo00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Escherichia coli O44:H18 042 (EAEC)
Class
Metabolism; Carbohydrate metabolism
Pathway map
elo00630  Glyoxylate and dicarboxylate metabolism
elo00630

Module
elo_M00012  Glyoxylate cycle [PATH:elo00630]
elo_M00621  Glycine cleavage system [PATH:elo00630]
Other DBs
GO: 0046487 0043648
Organism
Escherichia coli O44:H18 042 (EAEC) [GN:elo]
Gene
EC042_0115  lpdA; dihydrolipoyl dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenase complexes) [KO:K00382] [EC:1.8.1.4]
EC042_0117  acnB; aconitate hydratase 2 (citrate hydro-lyase 2) [KO:K01682] [EC:4.2.1.3 4.2.1.99]
EC042_0369  prpC; 2-methylcitrate synthase [KO:K01659] [EC:2.3.3.5]
EC042_0551  gcl; glyoxylate carboligase (tartronate-semialdehyde synthase) [KO:K01608] [EC:4.1.1.47]
EC042_0552  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
EC042_0553  glxR; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
EC042_0557  glxK; glycerate kinase 1 [KO:K00865] [EC:2.7.1.165]
EC042_0737  gltA; citrate synthase [KO:K01647] [EC:2.3.3.1]
EC042_0753  [KO:K04835] [EC:4.3.1.2]
EC042_0754  mutE; methylaspartate mutase E chain [KO:K19268] [EC:5.4.99.1]
EC042_0756  mamA; methylaspartate mutase S chain [KO:K01846] [EC:5.4.99.1]
EC042_1098  [KO:K12972] [EC:1.1.1.79 1.1.1.81]
EC042_1288  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
EC042_1401  acnA; aconitate hydratase 1 (citrate hydro-lyase 1) [KO:K27802]
EC042_1546  aldA; aldehyde dehydrogenase A [KO:K07248] [EC:1.2.1.22 1.2.1.21]
EC042_1897  katE; catalase HPII [KO:K03781] [EC:1.11.1.6]
EC042_1965  [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
EC042_2017  eda; KHG/KDPG aldolase [includes: 4-hydroxy-2-oxoglutarate aldolase; 2 dehydro-3-deoxy-phosphogluconate aldolase] [KO:K01625] [EC:4.1.2.14 4.1.3.42]
EC042_2465  atoB; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
EC042_2594  [KO:K07749] [EC:2.8.3.16]
EC042_2755  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
EC042_2997  fucO; lactaldehyde reductase (propanediol oxidoreductase) [KO:K00048] [EC:1.1.1.77]
EC042_3042  [KO:K00626] [EC:2.3.1.9]
EC042_3114  gcvP; glycine dehydrogenase [decarboxylating] [KO:K00281] [EC:1.4.4.2]
EC042_3115  gcvH; glycine cleavage system H protein [KO:K02437]
EC042_3116  gcvT; aminomethyltransferase (glycine cleavage system protein) [KO:K00605] [EC:2.1.2.10]
EC042_3126  sbm; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
EC042_3258  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
EC042_3260  glcF; glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
EC042_3261  glcE; glycolate oxidase subunit [KO:K11472] [EC:1.1.99.14]
EC042_3262  glcD; glycolate oxidase subunit [KO:K00104] [EC:1.1.99.14]
EC042_3355  ttdA; L-tartrate dehydratase subunit alpha [KO:K03779] [EC:4.2.1.32]
EC042_3356  ttdB; L-tartrate dehydratase subunit beta [KO:K03780] [EC:4.2.1.32]
EC042_3414  garK; glycerate kinase 2 [KO:K00865] [EC:2.7.1.165]
EC042_3415  garR; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
EC042_3521  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
EC042_3646  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
EC042_3859  tkrA; 2-ketogluconate reductase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
EC042_4243  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
EC042_4266  fdoI; formate dehydrogenase, cytochrome b556(fdo) subunit [KO:K00127]
EC042_4267  fdoH; formate dehydrogenase-O, iron-sulfur subunit [KO:K00124]
EC042_4268  fdoG; formate dehydrogenase-O, major subunit [KO:K00123] [EC:1.17.1.9]
EC042_4376  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
EC042_4377  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
EC042_4440  acs; acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00049  L-Aspartate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C05840  Iminoaspartate
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C19838  D-erythro-3-Hydroxyaspartate
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
elo00010  Glycolysis / Gluconeogenesis
elo00020  Citrate cycle (TCA cycle)
elo00030  Pentose phosphate pathway
elo00053  Ascorbate and aldarate metabolism
elo00071  Fatty acid degradation
elo00230  Purine metabolism
elo00250  Alanine, aspartate and glutamate metabolism
elo00260  Glycine, serine and threonine metabolism
elo00270  Cysteine and methionine metabolism
elo00620  Pyruvate metabolism
elo00710  Carbon fixation by Calvin cycle
elo00750  Vitamin B6 metabolism
elo00910  Nitrogen metabolism
KO pathway
ko00630   

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