KEGG   PATHWAY: elu00630
Entry
elu00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Escherichia coli UM146
Class
Metabolism; Carbohydrate metabolism
Pathway map
elu00630  Glyoxylate and dicarboxylate metabolism
elu00630

Module
elu_M00012  Glyoxylate cycle [PATH:elu00630]
elu_M00621  Glycine cleavage system [PATH:elu00630]
Other DBs
GO: 0046487 0043648
Organism
Escherichia coli UM146 [GN:elu]
Gene
UM146_20135  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
UM146_20540  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
UM146_20130  malate synthase [KO:K01638] [EC:2.3.3.9]
UM146_01520  malate synthase G [KO:K01638] [EC:2.3.3.9]
UM146_00230  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
UM146_14020  gltA; type II citrate synthase [KO:K01647] [EC:2.3.3.1]
UM146_10390  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
UM146_13795  hypothetical protein [KO:K01681] [EC:4.2.1.3]
UM146_23395  bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
UM146_05680  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
UM146_02205  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
UM146_01945  hypothetical protein [KO:K01847] [EC:5.4.99.2]
UM146_01500  glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
UM146_01505  glcE; glycolate oxidase FAD binding subunit [KO:K11472] [EC:1.1.99.14]
UM146_01510  glcF; glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
UM146_08490  katE; hydroperoxidase II [KO:K03781] [EC:1.11.1.6]
UM146_12160  putative dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
UM146_17935  2-ketoaldonate reductase/glyoxylate reductase B [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
UM146_16980  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
UM146_19590  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
UM146_03965  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
UM146_02010  glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
UM146_02000  gcvT; glycine cleavage system aminomethyltransferase T [KO:K00605] [EC:2.1.2.10]
UM146_20425  putative dihydrolipoyl dehydrogenase, E3 component (lpd-like) protein [KO:K00382] [EC:1.8.1.4]
UM146_23385  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
UM146_02005  glycine cleavage system protein H [KO:K02437]
UM146_22370  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
UM146_14820  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
UM146_14815  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
UM146_22365  putative regulatory protein GclR [KO:K01816] [EC:5.3.1.22]
UM146_14810  tartronate semialdehyde reductase, NADH-dependent [KO:K00042] [EC:1.1.1.60]
UM146_00725  garR; tartronate semialdehyde reductase [KO:K00042] [EC:1.1.1.60]
UM146_22360  putative 3-hydroxyisobutyrate dehydrogenase GhbD [KO:K00042] [EC:1.1.1.60]
UM146_14790  glycerate kinase II [KO:K00865] [EC:2.7.1.165]
UM146_00730  glycerate kinase I [KO:K00865] [EC:2.7.1.165]
UM146_09930  aldehyde dehydrogenase A [KO:K07248] [EC:1.2.1.22 1.2.1.21]
UM146_02570  L-1,2-propanediol oxidoreductase [KO:K00048] [EC:1.1.1.77]
UM146_00995  tartrate dehydratase subunit alpha [KO:K03779] [EC:4.2.1.32]
UM146_00990  L(+)-tartrate dehydratase subunit beta [KO:K03780] [EC:4.2.1.32]
UM146_07905  keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
UM146_19700  formate dehydrogenase-O, large subunit [KO:K00123] [EC:1.17.1.9]
UM146_19705  formate dehydrogenase-O, large subunit [KO:K00123] [EC:1.17.1.9]
UM146_19695  formate dehydrogenase-O, iron-sulfur subunit [KO:K00124]
UM146_19690  formate dehydrogenase-O subunit gamma [KO:K00127]
UM146_10910  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
UM146_04735  putative oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
elu00010  Glycolysis / Gluconeogenesis
elu00020  Citrate cycle (TCA cycle)
elu00030  Pentose phosphate pathway
elu00053  Ascorbate and aldarate metabolism
elu00071  Fatty acid degradation
elu00230  Purine metabolism
elu00250  Alanine, aspartate and glutamate metabolism
elu00260  Glycine, serine and threonine metabolism
elu00620  Pyruvate metabolism
elu00710  Carbon fixation by Calvin cycle
elu00750  Vitamin B6 metabolism
elu00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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