KEGG   PATHWAY: gfu00230
Entry
gfu00230                    Pathway                                
Name
Purine metabolism - Gemmobacter fulvus
Class
Metabolism; Nucleotide metabolism
Pathway map
gfu00230  Purine metabolism
gfu00230

Module
gfu_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:gfu00230]
gfu_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:gfu00230]
gfu_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:gfu00230]
gfu_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:gfu00230]
gfu_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:gfu00230]
gfu_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:gfu00230]
gfu_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:gfu00230]
Other DBs
GO: 0006163 0042278
Organism
Gemmobacter fulvus [GN:gfu]
Gene
KM031_13795  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
KM031_00270  alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
KM031_14260  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
KM031_00540  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
KM031_15660  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
KM031_04565  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
KM031_01460  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
KM031_03600  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
KM031_03595  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
KM031_04570  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
KM031_05495  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
KM031_05490  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
KM031_03605  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
KM031_05220  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
KM031_15245  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
KM031_08140  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
KM031_03620  5'-nucleotidase/apyrase family protein [KO:K11751] [EC:3.1.3.5 3.6.1.45]
KM031_02865  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
KM031_03780  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
KM031_05445  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
KM031_00795  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
KM031_00370  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
KM031_00210  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
KM031_09310  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
KM031_04355  gpt; xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
KM031_17125  molybdopterin-dependent oxidoreductase [KO:K00087] [EC:1.17.1.4]
KM031_13110  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
KM031_13115  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
KM031_00740  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
KM031_03185  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
KM031_00490  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
KM031_01915  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
KM031_07935  adenosylcobalamin-dependent ribonucleoside-diphosphate reductase [KO:K00525] [EC:1.17.4.1]
KM031_09520  nrdE; class 1b ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
KM031_09515  nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
KM031_16300  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
KM031_09395  HD family hydrolase [KO:K06952] [EC:3.1.3.89]
KM031_11630  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
KM031_01070  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
KM031_15045  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
KM031_19710  CHASE2 domain-containing protein [KO:K01768] [EC:4.6.1.1]
KM031_04050  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
KM031_13800  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
KM031_10780  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
KM031_06170  ade; adenine deaminase [KO:K01486] [EC:3.5.4.2]
KM031_12725  bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
KM031_05735  YmdB family metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
KM031_12185  adenylate kinase [KO:K00939] [EC:2.7.4.3]
KM031_14075  adenylate kinase [KO:K00939] [EC:2.7.4.3]
KM031_00115  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
KM031_05465  bifunctional sulfate adenylyltransferase/adenylylsulfate kinase [KO:K00958] [EC:2.7.7.4]
KM031_13235  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
KM031_19795  aspartate/glutamate racemase family protein [KO:K16841] [EC:5.1.99.3]
KM031_13240  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
KM031_13245  (S)-ureidoglycine aminohydrolase [KO:K14977] [EC:3.5.3.26]
KM031_13250  ureidoglycolate lyase [KO:K01483] [EC:4.3.2.3]
KM031_09050  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
KM031_09055  urease subunit beta [KO:K01429] [EC:3.5.1.5]
KM031_09065  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
gfu00030  Pentose phosphate pathway
gfu00220  Arginine biosynthesis
gfu00250  Alanine, aspartate and glutamate metabolism
gfu00260  Glycine, serine and threonine metabolism
gfu00340  Histidine metabolism
gfu00630  Glyoxylate and dicarboxylate metabolism
gfu00730  Thiamine metabolism
gfu00740  Riboflavin metabolism
gfu00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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