KEGG   PATHWAY: ggo00330
Entry
ggo00330                    Pathway                                
Name
Arginine and proline metabolism - Gorilla gorilla gorilla (western lowland gorilla)
Class
Metabolism; Amino acid metabolism
Pathway map
ggo00330  Arginine and proline metabolism
ggo00330

Module
ggo_M00015  Proline biosynthesis, glutamate => proline [PATH:ggo00330]
ggo_M00047  Creatine pathway [PATH:ggo00330]
ggo_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:ggo00330]
ggo_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:ggo00330]
ggo_M00970  Proline degradation, proline => glutamate [PATH:ggo00330]
ggo_M00972  Proline metabolism [PATH:ggo00330]
Other DBs
GO: 0006525 0006560
Organism
Gorilla gorilla gorilla (western lowland gorilla) [GN:ggo]
Gene
101125347  PRODH; proline dehydrogenase 1, mitochondrial isoform X1 [KO:K00318] [EC:1.5.5.2]
101125452  CKM; creatine kinase M-type [KO:K27382]
101126256  LAP3; cytosol aminopeptidase isoform X1 [KO:K11142] [EC:3.4.11.1 3.4.11.5]
101126518  CKMT2; creatine kinase S-type, mitochondrial isoform X1 [KO:K00933] [EC:2.7.3.2]
101126755  CNDP2; cytosolic non-specific dipeptidase [KO:K08660] [EC:3.4.13.18]
101126967  CKMT1B; creatine kinase U-type, mitochondrial isoform X2 [KO:K00933] [EC:2.7.3.2]
101127299  SRM; spermidine synthase [KO:K00797] [EC:2.5.1.16]
101127378  CNDP1; beta-Ala-His dipeptidase isoform X1 [KO:K05604] [EC:3.4.13.20]
101127462  DAO; D-amino-acid oxidase isoform X1 [KO:K00273] [EC:1.4.3.3]
101128007  NOS3; nitric oxide synthase 3 isoform X1 [KO:K13242] [EC:1.14.13.39]
101128406  ODC1; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
101130617  ALDH3A2; aldehyde dehydrogenase family 3 member A2 isoform X3 [KO:K00128] [EC:1.2.1.3]
101130794  AGMAT; guanidino acid hydrolase, mitochondrial [KO:K27001]
101130817  PYCR2; pyrroline-5-carboxylate reductase 2 isoform X1 [KO:K00286] [EC:1.5.1.2]
101130918  ALDH18A1; delta-1-pyrroline-5-carboxylate synthase isoform X2 [KO:K12657] [EC:2.7.2.11 1.2.1.41]
101131156  GOT1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
101131512  AZIN2; antizyme inhibitor 2 [KO:K01583] [EC:4.1.1.19]
101131612  P4HA1; prolyl 4-hydroxylase subunit alpha-1 isoform X1 [KO:K00472] [EC:1.14.11.2]
101133425  SMOX; spermine oxidase isoform X2 [KO:K12259] [EC:1.5.3.16 1.5.3.-]
101133589  CARNS1; carnosine synthase 1 isoform X1 [KO:K14755] [EC:6.3.2.11]
101133624  ARG2; arginase-2, mitochondrial [KO:K01476] [EC:3.5.3.1]
101133984  P4HA2; prolyl 4-hydroxylase subunit alpha-2 isoform X1 [KO:K00472] [EC:1.14.11.2]
101134923  NOS2; nitric oxide synthase, inducible isoform X1 [KO:K13241] [EC:1.14.13.39]
101136287  SMS; spermine synthase isoform X1 [KO:K00802] [EC:2.5.1.22]
101136541  ALDH4A1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial isoform X2 [KO:K00294] [EC:1.2.1.88]
101137000  AMD1; S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
101138620  ALDH1B1; aldehyde dehydrogenase X, mitochondrial [KO:K00128] [EC:1.2.1.3]
101139591  SAT1; diamine acetyltransferase 1 isoform X1 [KO:K00657] [EC:2.3.1.57]
101140073  OAT; ornithine aminotransferase, mitochondrial [KO:K00819] [EC:2.6.1.13]
101141308  MAOA; amine oxidase [flavin-containing] A [KO:K00274] [EC:1.4.3.4]
101141911  MAOB; amine oxidase [flavin-containing] B [KO:K00274] [EC:1.4.3.4]
101143694  CKB; creatine kinase B-type isoform X1 [KO:K00933] [EC:2.7.3.2]
101143792  P4HA3; prolyl 4-hydroxylase subunit alpha-3 [KO:K00472] [EC:1.14.11.2]
101144802  GATM; glycine amidinotransferase, mitochondrial [KO:K00613] [EC:2.1.4.1]
101145709  AOC1; amiloride-sensitive amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
101146743  ARG1; arginase-1 [KO:K01476] [EC:3.5.3.1]
101146844  [KO:K00797] [EC:2.5.1.16]
101147071  NOS1; nitric oxide synthase 1 isoform X1 [KO:K13240] [EC:1.14.13.39]
101148329  GOT1L1; putative aspartate aminotransferase, cytoplasmic 2 isoform X1 [KO:K14454] [EC:2.6.1.1]
101148545  ALDH7A1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
101149382  [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
101150449  GAMT; guanidinoacetate N-methyltransferase isoform X2 [KO:K00542] [EC:2.1.1.2]
101150906  ALDH2; aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
101150932  GOT2; aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
101151045  L3HYPDH; trans-3-hydroxy-L-proline dehydratase isoform X1 [KO:K18384] [EC:4.2.1.77]
101152129  [KO:K00933] [EC:2.7.3.2]
101153634  PYCR3; pyrroline-5-carboxylate reductase 3 [KO:K00286] [EC:1.5.1.2]
101154009  HOGA1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X1 [KO:K18123] [EC:4.1.3.16]
101154127  ALDH9A1; 4-trimethylaminobutyraldehyde dehydrogenase [KO:K00149] [EC:1.2.1.47 1.2.1.3]
101154315  PRODH2; hydroxyproline dehydrogenase isoform X1 [KO:K11394] [EC:1.5.5.3]
115931957  [KO:K00318] [EC:1.5.5.2]
115935842  [KO:K00128] [EC:1.2.1.3]
129524687  [KO:K00128] [EC:1.2.1.3]
129528018  SAT2; thialysine N-epsilon-acetyltransferase [KO:K00657] [EC:2.3.1.57]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
C20560  N1-(3-Aminopropyl)agmatine
C22886  N1-[(S)-3-amino-3-carboxypropyl]agmatine
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
ggo00020  Citrate cycle (TCA cycle)
ggo00220  Arginine biosynthesis
ggo00250  Alanine, aspartate and glutamate metabolism
ggo00260  Glycine, serine and threonine metabolism
ggo00270  Cysteine and methionine metabolism
ggo00310  Lysine degradation
ggo00410  beta-Alanine metabolism
ggo00470  D-Amino acid metabolism
ggo00480  Glutathione metabolism
ggo00630  Glyoxylate and dicarboxylate metabolism
ggo00650  Butanoate metabolism
ggo00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   

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