KEGG   PATHWAY: hahs00230
Entry
hahs00230                   Pathway                                
Name
Purine metabolism - Halanaeroarchaeum sp. HSR-CO
Class
Metabolism; Nucleotide metabolism
Pathway map
hahs00230  Purine metabolism
hahs00230

Module
hahs_M00005  PRPP biosynthesis, ribose-5P => PRPP [PATH:hahs00230]
hahs_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:hahs00230]
hahs_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:hahs00230]
hahs_M00968  Pentose bisphosphate pathway (nucleoside degradation), archaea, nucleoside/NMP => 3-PGA/glycerone phosphate [PATH:hahs00230]
Other DBs
GO: 0006163 0042278
Organism
Halanaeroarchaeum sp. HSR-CO [GN:hahs]
Gene
HSRCO_0010  purO; Archaeal IMP cyclohydrolase [KO:K11176] [EC:3.5.4.10]
HSRCO_0083  guaB; IMP dehydrogenase/GMP reductase [KO:K00088] [EC:1.1.1.205]
HSRCO_0127  guaA; GMP synthase - Glutamine amidotransferase domain [KO:K01951] [EC:6.3.5.2]
HSRCO_0203  prsA; Phosphoribosylpyrophosphate synthetase [KO:K00948] [EC:2.7.6.1]
HSRCO_0204  manB; Phosphomannomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
HSRCO_0588  [KO:K01515] [EC:3.6.1.13 3.6.1.-]
HSRCO_0904  guaA2; GMP synthase - Glutamine amidotransferase domain [KO:K01951] [EC:6.3.5.2]
HSRCO_0976  [KO:K01529]
HSRCO_1060  purH; AICAR transformylase/IMP cyclohydrolase PurH [KO:K01492] [EC:2.1.2.2 2.1.2.3]
HSRCO_1061  purB; Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
HSRCO_1177  arcC; Carbamate kinase [KO:K00926] [EC:2.7.2.2]
HSRCO_1197  apt2; Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein [KO:K00759] [EC:2.4.2.7]
HSRCO_1315  purK; Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) [KO:K01589] [EC:6.3.4.18]
HSRCO_1316  purE; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [KO:K01588] [EC:5.4.99.18]
HSRCO_1633  purD; Phosphoribosylamine-glycine ligase [KO:K01945] [EC:6.3.4.13]
HSRCO_1642  purA; Adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
HSRCO_1662  purL; Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain [KO:K23269]
HSRCO_1771  guaB2; IMP dehydrogenase/GMP reductase [KO:K00088] [EC:1.1.1.205]
HSRCO_1796  fap7; Broad-specificity NMP kinase [KO:K18532] [EC:2.7.4.3]
HSRCO_1896  purM; Phosphoribosylaminoimidazole (AIR) synthetase [KO:K01933] [EC:6.3.3.1]
HSRCO_1928  manB2; Phosphomannomutase [KO:K22199] [EC:5.4.2.7]
HSRCO_1964  adeC; Adenine deaminase [KO:K01486] [EC:3.5.4.2]
HSRCO_2004  ndk; Nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
HSRCO_2040  surE; putative acid phosphatase [KO:K03787] [EC:3.1.3.5 3.1.3.6]
HSRCO_2117  cyaB; Adenylate cyclase, class 2 (thermophilic) [KO:K05873] [EC:4.6.1.1]
HSRCO_2124  purD2; Phosphoribosylamine-glycine ligase [KO:K01945] [EC:6.3.4.13]
HSRCO_2129  adkA; Archaeal adenylate kinase [KO:K00939] [EC:2.7.4.3]
HSRCO_2200  purF; Glutamine phosphoribosylpyrophosphate amidotransferase [KO:K00764] [EC:2.4.2.14]
HSRCO_2328  nrdA; Ribonucleotide reductase associated ATP-cone domain [KO:K00525] [EC:1.17.4.1]
HSRCO_2363  adk; Adenylate kinase or related kinase [KO:K00939] [EC:2.7.4.3]
HSRCO_2516  guaA3; GMP synthase, PP-ATPase domain/subunit [KO:K01951] [EC:6.3.5.2]
HSRCO_2534  udp2; Uridine phosphorylase [KO:K26212]
HSRCO_2542  hit2; HIT family hydrolase [KO:K19710] [EC:2.7.7.53]
HSRCO_2582  nrdA2; Ribonucleotide reductase, alpha subunit [KO:K00525] [EC:1.17.4.1]
HSRCO_2585  purC; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase [KO:K01923] [EC:6.3.2.6]
HSRCO_2586  purS; Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component [KO:K23264]
HSRCO_2587  purL2; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain [KO:K23265]
HSRCO_2599  [KO:K01515] [EC:3.6.1.13 3.6.1.-]
HSRCO_2625  rdgB; Inosine/xanthosine triphosphate pyrophosphatase,all-alpha NTP-PPase family [KO:K01519] [EC:3.6.1.66]
HSRCO_2754  guaA4; GMP synthase - Glutamine amidotransferase domain [KO:K01951] [EC:6.3.5.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
hahs00030  Pentose phosphate pathway
hahs00220  Arginine biosynthesis
hahs00250  Alanine, aspartate and glutamate metabolism
hahs00260  Glycine, serine and threonine metabolism
hahs00340  Histidine metabolism
hahs00630  Glyoxylate and dicarboxylate metabolism
hahs00730  Thiamine metabolism
hahs00740  Riboflavin metabolism
hahs00790  Folate biosynthesis
KO pathway
ko00230   

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