KEGG   PATHWAY: hahs00630
Entry
hahs00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Halanaeroarchaeum sp. HSR-CO
Class
Metabolism; Carbohydrate metabolism
Pathway map
hahs00630  Glyoxylate and dicarboxylate metabolism
hahs00630

Module
hahs_M00012  Glyoxylate cycle [PATH:hahs00630]
hahs_M00621  Glycine cleavage system [PATH:hahs00630]
hahs_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:hahs00630]
hahs_M00968  Pentose bisphosphate pathway (nucleoside degradation), archaea, nucleoside/NMP => 3-PGA/glycerone phosphate [PATH:hahs00630]
Other DBs
GO: 0046487 0043648
Organism
Halanaeroarchaeum sp. HSR-CO [GN:hahs]
Gene
HSRCO_0084  mdh; Malate/lactate dehydrogenase [KO:K00024] [EC:1.1.1.37]
HSRCO_0369  gltA; Citrate synthase [KO:K01647] [EC:2.3.3.1]
HSRCO_0370  gltA2; Citrate synthase [KO:K01659] [EC:2.3.3.5]
HSRCO_0394  acnA; Aconitase A [KO:K27802]
HSRCO_0424  hybA5; Fe-S-cluster-containing dehydrogenase component [KO:K00124]
HSRCO_0425  bisC4; Anaerobic dehydrogenase [KO:K00123] [EC:1.17.1.9]
HSRCO_0609  acs; Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase [KO:K01895] [EC:6.2.1.1]
HSRCO_1015  gckA; Glycerate kinase [KO:K11529] [EC:2.7.1.165]
HSRCO_1051  gltB; Glutamate synthase [KO:K00284] [EC:1.4.7.1]
HSRCO_1099  gloA2; Lactoylglutathione lyase or related enzyme [KO:K05606] [EC:5.1.99.1]
HSRCO_1100  sbm; Methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
HSRCO_1106  acs2; Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase [KO:K01895] [EC:6.2.1.1]
HSRCO_1233  purU; Formyltetrahydrofolate hydrolase [KO:K01433] [EC:3.5.1.10]
HSRCO_1330  sbm2; Methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
HSRCO_1333  sbm3; Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding) [KO:K01849] [EC:5.4.99.2]
HSRCO_1337  paaJ; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
HSRCO_1343  rbcL; Ribulose 1,5-bisphosphate carboxylase, large subunit [KO:K01601] [EC:4.1.1.39]
HSRCO_1349  acs3; Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase [KO:K01895] [EC:6.2.1.1]
HSRCO_1377  cof; HAD superfamily hydrolase [KO:K22223] [EC:3.1.3.18]
HSRCO_1726  paaJ2; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
HSRCO_1899  glnA; Glutamine synthetase [KO:K01915] [EC:6.3.1.2]
HSRCO_2166  glyA; Glycine/serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
HSRCO_2206  gph3; HAD superfamily hydrolase [KO:K01091] [EC:3.1.3.18]
HSRCO_2224  pucG; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
HSRCO_2262  [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
HSRCO_2263  [KO:K22568] [EC:6.4.1.2 6.4.1.3]
HSRCO_2264  [KO:K19312] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
HSRCO_2293  gcvP; Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain [KO:K00283] [EC:1.4.4.2]
HSRCO_2294  gcvP2; Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain [KO:K00282] [EC:1.4.4.2]
HSRCO_2295  gcvH; Glycine cleavage system H protein (lipoate-binding) [KO:K02437]
HSRCO_2296  gcvT; Glycine cleavage system T protein (aminomethyltransferase) [KO:K00605] [EC:2.1.2.10]
HSRCO_2454  gph5; HAD superfamily hydrolase [KO:K01091] [EC:3.1.3.18]
HSRCO_2657  prpB; PEP phosphonomutase or related enzyme [KO:K01637] [EC:4.1.3.1 4.1.3.30]
HSRCO_2658  mcl2; Beta-methylmalyl-CoA lyase, Citrate lyase beta subunit family [KO:K19282] [EC:4.1.3.24 3.1.2.30]
HSRCO_2662  glnA2; Glutamine synthetase [KO:K01915] [EC:6.3.1.2]
HSRCO_2691  lpd3; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme [KO:K00382] [EC:1.8.1.4]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00049  L-Aspartate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C05840  Iminoaspartate
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C19838  D-erythro-3-Hydroxyaspartate
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
hahs00010  Glycolysis / Gluconeogenesis
hahs00020  Citrate cycle (TCA cycle)
hahs00030  Pentose phosphate pathway
hahs00053  Ascorbate and aldarate metabolism
hahs00071  Fatty acid degradation
hahs00230  Purine metabolism
hahs00250  Alanine, aspartate and glutamate metabolism
hahs00260  Glycine, serine and threonine metabolism
hahs00270  Cysteine and methionine metabolism
hahs00620  Pyruvate metabolism
hahs00710  Carbon fixation by Calvin cycle
hahs00750  Vitamin B6 metabolism
hahs00910  Nitrogen metabolism
KO pathway
ko00630   

DBGET integrated database retrieval system