KEGG   PATHWAY: halj00630
Entry
halj00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Haloarcula sp. JP-L23
Class
Metabolism; Carbohydrate metabolism
Pathway map
halj00630  Glyoxylate and dicarboxylate metabolism
halj00630

Module
halj_M00621  Glycine cleavage system [PATH:halj00630]
halj_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:halj00630]
Other DBs
GO: 0046487 0043648
Organism
Haloarcula sp. JP-L23 [GN:halj]
Gene
G9465_00420  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
G9465_00430  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
G9465_08390  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
G9465_11155  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
G9465_20270  acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
G9465_23100  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
G9465_02650  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
G9465_03510  citrate synthase [KO:K01647] [EC:2.3.3.1]
G9465_04440  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
G9465_09050  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
G9465_09095  thiolase family protein [KO:K00626] [EC:2.3.1.9]
G9465_11490  thiolase family protein [KO:K00626] [EC:2.3.1.9]
G9465_18160  thiolase family protein [KO:K00626] [EC:2.3.1.9]
G9465_21940  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
G9465_23120  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
G9465_03195  MaoC family dehydratase [KO:K17865] [EC:4.2.1.55]
G9465_21230  MaoC family dehydratase [KO:K17865] [EC:4.2.1.55]
G9465_22435  MaoC family dehydratase [KO:K17865] [EC:4.2.1.55]
G9465_08365  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
G9465_24105  hypothetical protein [KO:K05606] [EC:5.1.99.1]
G9465_08580  acyl dehydratase [KO:K14449] [EC:4.2.1.148]
G9465_13620  acetyl-CoA carboxylase biotin carboxylase subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
G9465_11455  acyl-CoA carboxylase subunit beta [KO:K19312] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
G9465_13630  acyl-CoA carboxylase subunit beta [KO:K19312] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
G9465_11460  hypothetical protein [KO:K22568] [EC:6.4.1.2 6.4.1.3]
G9465_13625  acc operon protein [KO:K22568] [EC:6.4.1.2 6.4.1.3]
G9465_09030  cobalamin B12-binding domain-containing protein [KO:K01849] [EC:5.4.99.2]
G9465_08375  methylmalonyl-CoA mutase family protein [KO:K01848] [EC:5.4.99.2]
G9465_14665  methylmalonyl-CoA mutase family protein [KO:K01848] [EC:5.4.99.2]
G9465_08570  methylaspartate mutase subunit E [KO:K19268] [EC:5.4.99.1]
G9465_06705  methylaspartate mutase subunit S [KO:K01846] [EC:5.4.99.1]
G9465_08565  methylaspartate mutase subunit S [KO:K01846] [EC:5.4.99.1]
G9465_08575  methylaspartate ammonia-lyase [KO:K04835] [EC:4.3.1.2]
G9465_08560  CoA transferase [KO:K19280] [EC:2.8.3.26]
G9465_08585  citrate lyase subunit beta [KO:K19281] [EC:4.1.3.24]
G9465_11590  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
G9465_16190  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
G9465_15360  phosphoglycolate phosphatase [KO:K22223] [EC:3.1.3.18]
G9465_06550  alanine--glyoxylate aminotransferase family protein [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
G9465_07175  gltB; glutamate synthase large subunit [KO:K00284] [EC:1.4.7.1]
G9465_07910  gltB; glutamate synthase large subunit [KO:K00284] [EC:1.4.7.1]
G9465_03695  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
G9465_21085  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
G9465_12845  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
G9465_20220  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
G9465_21780  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
G9465_23445  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
G9465_15240  aminomethyl-transferring glycine dehydrogenase subunit GcvPA [KO:K00282] [EC:1.4.4.2]
G9465_21760  aminomethyl-transferring glycine dehydrogenase subunit GcvPA [KO:K00282] [EC:1.4.4.2]
G9465_15235  glycine dehydrogenase subunit 2 [KO:K00283] [EC:1.4.4.2]
G9465_21765  glycine dehydrogenase subunit 2 [KO:K00283] [EC:1.4.4.2]
G9465_05670  aminomethyl transferase family protein [KO:K00605] [EC:2.1.2.10]
G9465_15250  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
G9465_21750  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
G9465_01785  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
G9465_21770  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
G9465_15245  gcvH; glycine cleavage system protein GcvH [KO:K02437]
G9465_21755  gcvH; glycine cleavage system protein GcvH [KO:K02437]
G9465_10925  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
G9465_23275  NAD(P)-dependent oxidoreductase [KO:K00042] [EC:1.1.1.60]
G9465_21175  DUF4147 domain-containing protein [KO:K11529] [EC:2.7.1.165]
G9465_06275  fuculose phosphate aldolase [KO:K01636] [EC:4.1.2.-]
G9465_00890  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
G9465_05905  molybdopterin-dependent oxidoreductase [KO:K00123] [EC:1.17.1.9]
G9465_05910  4Fe-4S dicluster domain-containing protein [KO:K00124]
G9465_17605  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
halj00010  Glycolysis / Gluconeogenesis
halj00020  Citrate cycle (TCA cycle)
halj00030  Pentose phosphate pathway
halj00053  Ascorbate and aldarate metabolism
halj00071  Fatty acid degradation
halj00230  Purine metabolism
halj00250  Alanine, aspartate and glutamate metabolism
halj00260  Glycine, serine and threonine metabolism
halj00620  Pyruvate metabolism
halj00710  Carbon fixation by Calvin cycle
halj00750  Vitamin B6 metabolism
halj00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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