Homo sapiens (human): 10097 Help Entry 10097             CDS       T01001                                  Symbol ACTR2, ARP2 Name (RefSeq) actin related protein 2   KO K17260   actin-related protein 2 Organism hsa  Homo sapiens (human) Pathway hsa04144   Endocytosis hsa04530   Tight junction hsa04666   Fc gamma R-mediated phagocytosis hsa04810   Regulation of actin cytoskeleton hsa05100   Bacterial invasion of epithelial cells hsa05130   Pathogenic Escherichia coli infection hsa05131   Shigellosis hsa05132   Salmonella infection hsa05135   Yersinia infection Network nt06180  Pathogenic Escherichia coli nt06181  Salmonella nt06182  Shigella   Element N01066   ARNO-ARF-ACTB_G signaling pathway N01067   Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway N01078   EGF-EGFR-Actin signaling pathway N01079   Shigella IpaC to Actin signaling pathway N01086   Escherichia EspT to RAC signaling pathway N01092   Escherichia Eae/Tir to Actin signaling pathway N01094   Escherichia Eae/Tir/TccP to Actin signaling pathway N01096   Escherichia Map to CDC42 signaling pathway N01128   Salmonella SopE to RAC signaling pathway N01129   Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway N01287   Tight junction-Actin signaling pathway Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     10097 (ACTR2)   09144 Cellular community - eukaryotes    04530 Tight junction     10097 (ACTR2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     10097 (ACTR2)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     10097 (ACTR2)  09160 Human Diseases   09171 Infectious disease: bacterial    05130 Pathogenic Escherichia coli infection     10097 (ACTR2)    05132 Salmonella infection     10097 (ACTR2)    05131 Shigellosis     10097 (ACTR2)    05135 Yersinia infection     10097 (ACTR2)    05100 Bacterial invasion of epithelial cells     10097 (ACTR2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     10097 (ACTR2)   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:hsa04812]     10097 (ACTR2)    04147 Exosome [BR:hsa04147]     10097 (ACTR2) Membrane trafficking [BR:hsa04131]  Others   Actin-binding proteins    Arp2/3 complex     10097 (ACTR2) Cytoskeleton proteins [BR:hsa04812]  Eukaryotic cytoskeleton proteins   Actin filaments / Microfilaments    Actin-binding proteins     Arp2/3 complex      10097 (ACTR2) Exosome [BR:hsa04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    10097 (ACTR2)   Exosomal proteins of other body fluids (saliva and urine)    10097 (ACTR2)   Exosomal proteins of bladder cancer cells    10097 (ACTR2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Actin Motif Other DBs NCBI-GeneID:  10097 NCBI-ProteinID:  NP_005713 OMIM:  604221 HGNC:  169 Ensembl:  ENSG00000138071 UniProt:  P61160 Structure PDB LinkDB All DBs Position 2:65227831..65271253 Genome browser AA seq 394 aa AA seqDB search MDSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVGNIEIKDLMVGDE ASELRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNR EKIVEVMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTR RLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVL VESYTLPDGRIIKVGGERFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKH IVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSKFKIRIEDPPRRKHMVFLGGAV LADIMKDKDNFWMTRQEYQEKGVRVLEKLGVTVR NT seq 1185 nt NT seq  +upstreamnt  +downstreamnt atggacagccagggcaggaaggtggtggtgtgcgacaacggcaccgggtttgtgaagtgt ggatatgcaggctctaactttccagaacacatcttcccagctttggttggaagacctatt atcagatcaaccaccaaagtgggaaacattgaaatcaaggatcttatggttggtgatgag gcaagtgaattacgatcaatgttagaagttaactaccctatggaaaatggcatagtacga aattgggatgacatgaaacacctgtgggactacacatttggaccagagaaacttaatata gataccagaaattgtaaaatcttactcacagaacctcctatgaacccaaccaaaaacaga gagaagattgtagaggtaatgtttgaaacttaccagttttccggtgtatatgtagccatc caggcagttctgactttgtacgctcaaggtttattgactggtgtagtggtagactctgga gatggtgtgactcacatttgcccagtatatgaaggcttttctctccctcatcttaccagg agactggatattgctgggagggatataactagatatcttatcaagctacttctgttgcga ggatacgccttcaaccactctgctgattttgaaacggttcgcatgattaaagaaaaactg tgttacgtgggatataatattgagcaagagcagaaactggccttagaaaccacagtatta gttgaatcttatacactcccagatggacgtatcatcaaagttgggggagagagatttgaa gcaccagaagctttatttcagcctcacttgatcaatgttgaaggagttggtgttgctgaa ttgctttttaacacaattcaggcagctgacattgataccagatctgaattctacaaacac attgtgctttctggagggtctactatgtatcctggcctgccatcacggttggaacgagaa cttaaacagctttacttagaacgagttttgaagggtgatgtggaaaaactttctaaattt aagatccgcattgaagacccaccccgcagaaagcacatggtattcctgggtggtgcagtt ctagcggatatcatgaaagacaaagacaacttttggatgacccgacaagagtaccaagaa aagggtgtccgtgtgctagagaaacttggtgtgactgttcgataa

Homo sapiens (human): 10096 Help Entry 10096             CDS       T01001                                  Symbol ACTR3, ARP3 Name (RefSeq) actin related protein 3   KO K18584   actin-related protein 3 Organism hsa  Homo sapiens (human) Pathway hsa04144   Endocytosis hsa04530   Tight junction hsa04666   Fc gamma R-mediated phagocytosis hsa04810   Regulation of actin cytoskeleton hsa05100   Bacterial invasion of epithelial cells hsa05130   Pathogenic Escherichia coli infection hsa05131   Shigellosis hsa05132   Salmonella infection hsa05135   Yersinia infection Network nt06180  Pathogenic Escherichia coli nt06181  Salmonella nt06182  Shigella   Element N01066   ARNO-ARF-ACTB_G signaling pathway N01067   Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway N01078   EGF-EGFR-Actin signaling pathway N01079   Shigella IpaC to Actin signaling pathway N01086   Escherichia EspT to RAC signaling pathway N01092   Escherichia Eae/Tir to Actin signaling pathway N01094   Escherichia Eae/Tir/TccP to Actin signaling pathway N01096   Escherichia Map to CDC42 signaling pathway N01128   Salmonella SopE to RAC signaling pathway N01129   Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway N01287   Tight junction-Actin signaling pathway Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     10096 (ACTR3)   09144 Cellular community - eukaryotes    04530 Tight junction     10096 (ACTR3)   09142 Cell motility    04810 Regulation of actin cytoskeleton     10096 (ACTR3)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     10096 (ACTR3)  09160 Human Diseases   09171 Infectious disease: bacterial    05130 Pathogenic Escherichia coli infection     10096 (ACTR3)    05132 Salmonella infection     10096 (ACTR3)    05131 Shigellosis     10096 (ACTR3)    05135 Yersinia infection     10096 (ACTR3)    05100 Bacterial invasion of epithelial cells     10096 (ACTR3)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     10096 (ACTR3)   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:hsa04812]     10096 (ACTR3)    04147 Exosome [BR:hsa04147]     10096 (ACTR3) Membrane trafficking [BR:hsa04131]  Others   Actin-binding proteins    Arp2/3 complex     10096 (ACTR3) Cytoskeleton proteins [BR:hsa04812]  Eukaryotic cytoskeleton proteins   Actin filaments / Microfilaments    Actin-binding proteins     Arp2/3 complex      10096 (ACTR3) Exosome [BR:hsa04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    10096 (ACTR3)   Exosomal proteins of other body fluids (saliva and urine)    10096 (ACTR3)   Exosomal proteins of bladder cancer cells    10096 (ACTR3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Actin MreB_Mbl FtsA ALP_N Robl_LC7 Motif Other DBs NCBI-GeneID:  10096 NCBI-ProteinID:  NP_005712 OMIM:  604222 HGNC:  170 Ensembl:  ENSG00000115091 UniProt:  P61158 Structure PDB LinkDB All DBs Position 2:113889934..113962596 Genome browser AA seq 418 aa AA seqDB search MAGRLPACVVDCGTGYTKLGYAGNTEPQFIIPSCIAIKESAKVGDQAQRRVMKGVDDLDF FIGDEAIEKPTYATKWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNTP ENREYTAEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPV AEGYVIGSCIKHIPIAGRDITYFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLVK EFNKYDTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEVV DEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVDARLKLSEELSGGRLKP KPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKKDYEEIGPSICRHNPVFGVMS NT seq 1257 nt NT seq  +upstreamnt  +downstreamnt atggcgggacggctgccggcctgtgtggtggactgtggcacggggtatacaaaactagga tatgctggaaatacagaaccacagtttatcatcccttcctgtattgctattaaggagtca gcaaaagtgggtgatcaagctcaaaggagggtgatgaaaggtgttgatgacctagacttc ttcattggtgatgaagcaatagaaaaacctacatatgcaacaaagtggccaatccgccat ggtatagttgaagattgggacttaatggaaaggtttatggagcaagtgatctttaaatat ttaagggcagaacctgaagaccattattttcttttgactgaacctccattgaatactcca gaaaacagggaatatactgctgaaataatgtttgagtccttcaatgttccaggcttgtac attgctgtgcaggctgttcttgccttagctgcatcttggacctcaagacaagtaggagaa cggacgttgaccggtacggtaatagacagtggagatggtgtcactcatgtcattcctgtg gctgaagggtatgtgattggcagctgtattaaacacattccaatcgcaggacgagatata acatattttattcagcaactgctgagagaccgagaagtaggaatccctccagaacaatcc ttggaaactgctaaggcagtaaaggagcgctatagttatgtctgcccagatttagtaaaa gaatttaacaagtatgatacagatgggtcaaaatggattaaacagtatactggaatcaat gctatctcaaagaaagagttttctatcgatgttggttatgagagatttttgggacctgaa atcttttttcatccagagtttgctaatccagactttacacaacctatctcagaagttgta gatgaagtaattcagaattgtcctattgatgtcagacgtcctctctacaagaatattgtc ctctctggaggttcaaccatgttcagggactttggacgtcgcttgcaaagagatttgaaa agaactgtagatgcccggctgaaattaagtgaggaattgagtggtggtagattgaagcca aaacctattgatgtacaagtcattacacaccacatgcagcgatatgcagtttggtttgga ggatcaatgctggcttccacgcctgagttctaccaagtatgccacaccaaaaaggattat gaagaaattggacctagcatttgtcgtcacaatccagtgtttggagtcatgtcgtaa

Homo sapiens (human): 10552 Help Entry 10552             CDS       T01001                                  Symbol ARPC1A, Arc40, HEL-68, HEL-S-307, SOP2Hs, SOP2L Name (RefSeq) actin related protein 2/3 complex subunit 1A   KO K05757   actin related protein 2/3 complex, subunit 1A/1B Organism hsa  Homo sapiens (human) Pathway hsa04144   Endocytosis hsa04530   Tight junction hsa04666   Fc gamma R-mediated phagocytosis hsa04810   Regulation of actin cytoskeleton hsa05100   Bacterial invasion of epithelial cells hsa05130   Pathogenic Escherichia coli infection hsa05131   Shigellosis hsa05132   Salmonella infection hsa05135   Yersinia infection Network nt06180  Pathogenic Escherichia coli nt06181  Salmonella nt06182  Shigella   Element N01066   ARNO-ARF-ACTB_G signaling pathway N01067   Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway N01078   EGF-EGFR-Actin signaling pathway N01079   Shigella IpaC to Actin signaling pathway N01086   Escherichia EspT to RAC signaling pathway N01092   Escherichia Eae/Tir to Actin signaling pathway N01094   Escherichia Eae/Tir/TccP to Actin signaling pathway N01096   Escherichia Map to CDC42 signaling pathway N01128   Salmonella SopE to RAC signaling pathway N01129   Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway N01287   Tight junction-Actin signaling pathway Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     10552 (ARPC1A)   09144 Cellular community - eukaryotes    04530 Tight junction     10552 (ARPC1A)   09142 Cell motility    04810 Regulation of actin cytoskeleton     10552 (ARPC1A)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     10552 (ARPC1A)  09160 Human Diseases   09171 Infectious disease: bacterial    05130 Pathogenic Escherichia coli infection     10552 (ARPC1A)    05132 Salmonella infection     10552 (ARPC1A)    05131 Shigellosis     10552 (ARPC1A)    05135 Yersinia infection     10552 (ARPC1A)    05100 Bacterial invasion of epithelial cells     10552 (ARPC1A)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     10552 (ARPC1A)   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:hsa04812]     10552 (ARPC1A) Membrane trafficking [BR:hsa04131]  Others   Actin-binding proteins    Arp2/3 complex     10552 (ARPC1A) Cytoskeleton proteins [BR:hsa04812]  Eukaryotic cytoskeleton proteins   Actin filaments / Microfilaments    Actin-binding proteins     Arp2/3 complex      10552 (ARPC1A) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  WD40 ANAPC4_WD40 Rax2 Motif Other DBs NCBI-GeneID:  10552 NCBI-ProteinID:  NP_006400 OMIM:  604220 HGNC:  703 Ensembl:  ENSG00000241685 UniProt:  Q92747 V9HVZ6 Structure PDB LinkDB All DBs Position 7:99325898..99366262 Genome browser AA seq 370 aa AA seqDB search MSLHQFLLEPITCHAWNRDRTQIALSPNNHEVHIYKKNGSQWVKAHELKEHNGHITGIDW APKSDRIVTCGADRNAYVWSQKDGVWKPTLVILRINRAATFVKWSPLENKFAVGSGARLI SVCYFESENDWWVSKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRVFSAYIKEVDEKP ASTPWGSKMPFGQLMSEFGGSGTGGWVHGVSFSASGSRLAWVSHDSTVSVADASKSVQVS TLKTEFLPLLSVSFVSENSVVAAGHDCCPMLFNYDDRGCLTFVSKLDIPKQSIQRNMSAM ERFRNMDKRATTEDRNTALETLHQNSITQVSIYEVDKQDCRKFCTTGIDGAMTIWDFKTL ESSIQGLRIM NT seq 1113 nt NT seq  +upstreamnt  +downstreamnt atgtcactgcatcagtttttactagagccaatcacctgtcatgcctggaacagggatcgt actcagattgccctcagtcccaataatcacgaagtgcacatctataagaagaacgggagc cagtgggtgaaagctcatgaactcaaggagcacaacggacacatcacaggtattgactgg gctcccaagagcgaccgcattgtcacttgtggggcagaccgcaatgcctatgtctggagt cagaaagatggtgtttggaagccaaccctggtgatcctgagaattaatcgcgcagctact tttgtgaagtggtcccccctagagaacaaatttgctgtgggaagtggagcacgactcatt tctgtttgttactttgagtctgaaaatgactggtgggtgagcaagcacattaaaaagccg attcgctccacagtcctcagcttggattggcatcccaacaacgttttgctggcagcagga tcatgtgacttcaaatgcagagtgttttctgcctacattaaagaagtggatgaaaagcca gccagcacgccctggggcagcaagatgccttttgggcagctgatgtcagagtttggtggc agtggcactggtggctgggtccacggggtaagcttctctgccagtgggagccgcctggcc tgggtcagccacgacagcaccgtgtctgttgctgatgcctcaaaaagtgtgcaggtctcg actctgaagacagagttcctgccgctcctaagtgtgtcatttgtctcagagaacagcgtc gtggctgctggccatgactgctgcccaatgctctttaactacgatgaccgcggctgcctg accttcgtctccaagttagatattccaaaacagagcatccaacgcaacatgtctgccatg gaacgcttccgcaacatggacaagagagccacaactgaggaccgcaacacggccttggag acgctgcaccagaatagcatcactcaagtctctatttatgaggtggacaagcaagattgt cgcaaattttgcactactggcatcgatggagccatgacaatttgggatttcaagaccctc gagtcttccatccagggcctccggataatgtga

Homo sapiens (human): 10095 Help Entry 10095             CDS       T01001                                  Symbol ARPC1B, ARC41, IMD71, PLTEID, p40-ARC, p41-ARC Name (RefSeq) actin related protein 2/3 complex subunit 1B   KO K05757   actin related protein 2/3 complex, subunit 1A/1B Organism hsa  Homo sapiens (human) Pathway hsa04144   Endocytosis hsa04530   Tight junction hsa04666   Fc gamma R-mediated phagocytosis hsa04810   Regulation of actin cytoskeleton hsa05100   Bacterial invasion of epithelial cells hsa05130   Pathogenic Escherichia coli infection hsa05131   Shigellosis hsa05132   Salmonella infection hsa05135   Yersinia infection Network nt06180  Pathogenic Escherichia coli nt06181  Salmonella nt06182  Shigella   Element N01066   ARNO-ARF-ACTB_G signaling pathway N01067   Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway N01078   EGF-EGFR-Actin signaling pathway N01079   Shigella IpaC to Actin signaling pathway N01086   Escherichia EspT to RAC signaling pathway N01092   Escherichia Eae/Tir to Actin signaling pathway N01094   Escherichia Eae/Tir/TccP to Actin signaling pathway N01096   Escherichia Map to CDC42 signaling pathway N01128   Salmonella SopE to RAC signaling pathway N01129   Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway N01287   Tight junction-Actin signaling pathway Disease H00093   Combined immunodeficiency Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     10095 (ARPC1B)   09144 Cellular community - eukaryotes    04530 Tight junction     10095 (ARPC1B)   09142 Cell motility    04810 Regulation of actin cytoskeleton     10095 (ARPC1B)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     10095 (ARPC1B)  09160 Human Diseases   09171 Infectious disease: bacterial    05130 Pathogenic Escherichia coli infection     10095 (ARPC1B)    05132 Salmonella infection     10095 (ARPC1B)    05131 Shigellosis     10095 (ARPC1B)    05135 Yersinia infection     10095 (ARPC1B)    05100 Bacterial invasion of epithelial cells     10095 (ARPC1B)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     10095 (ARPC1B)   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:hsa04812]     10095 (ARPC1B) Membrane trafficking [BR:hsa04131]  Others   Actin-binding proteins    Arp2/3 complex     10095 (ARPC1B) Cytoskeleton proteins [BR:hsa04812]  Eukaryotic cytoskeleton proteins   Actin filaments / Microfilaments    Actin-binding proteins     Arp2/3 complex      10095 (ARPC1B) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  WD40 ANAPC4_WD40 eIF2A Rax2 RMC1_N SH3_3 Motif Other DBs NCBI-GeneID:  10095 NCBI-ProteinID:  NP_005711 OMIM:  604223 HGNC:  704 Ensembl:  ENSG00000130429 UniProt:  O15143 A4D275 Structure PDB LinkDB All DBs Position 7:99374259..99394816 Genome browser AA seq 372 aa AA seqDB search MAYHSFLVEPISCHAWNKDRTQIAICPNNHEVHIYEKSGAKWTKVHELKEHNGQVTGIDW APESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCVRWAPNENKFAVGSGSRVI SICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIFSAYIKEVEERP APTPWGSKMPFGELMFESSSSCGWVHGVCFSASGSRVAWVSHDSTVCLADADKKMAVATL ASETLPLLALTFITDNSLVAAGHDCFPVLFTYDAAAGMLSFGGRLDVPKQSSQRGLTARE RFQNLDKKASSEGGTAAGAGLDSLHKNSVSQISVLSGGKAKCSQFCTTGMDGGMSIWDVK SLESALKDLKIK NT seq 1119 nt NT seq  +upstreamnt  +downstreamnt atggcctaccacagcttcctggtggagcccatcagctgccacgcctggaacaaggaccgc acccagattgccatctgccccaacaaccatgaggtgcatatctatgaaaagagcggtgcc aaatggaccaaggtgcacgagctcaaggagcacaacgggcaggtgacaggcatcgactgg gcccccgagagtaaccgtattgtgacctgcggcacagaccgcaacgcctacgtgtggacg ctgaagggccgcacatggaagcccacgctggtcatcctgcggatcaaccgggctgcccgc tgcgtgcgctgggcccccaacgagaacaagtttgctgtgggcagcggctctcgtgtgatc tccatctgttatttcgagcaggagaatgactggtgggtttgcaagcacatcaagaagccc atccgctccaccgtcctcagcctggactggcaccccaacaatgtgctgctggctgccggc tcctgtgacttcaagtgtcggatcttttcagcctacatcaaggaggtggaggaacggccg gcacccaccccgtggggctccaagatgccctttggggaactgatgttcgaatccagcagt agctgcggctgggtacatggcgtctgtttctcagccagcgggagccgcgtggcctgggta agccacgacagcaccgtctgcctggctgatgccgacaagaagatggccgtcgcgactctg gcctctgaaacactaccactgctggcgctgaccttcatcacagacaacagcctggtggca gcgggccacgactgcttcccggtgctgttcacctatgacgccgccgcggggatgctgagc ttcggcgggcggctggacgttcctaagcagagctcgcagcgtggcttgacggcccgcgag cgcttccagaacctggacaagaaggcgagctccgagggtggcacggctgcgggcgcgggc ctagactcgctgcacaagaacagcgtcagccagatctcggtgctcagcggcggcaaggcc aagtgctcgcagttctgcaccactggcatggatggcggcatgagtatctgggatgtgaag agcttggagtcagccttgaaggacctcaagatcaaatga

Homo sapiens (human): 10109 Help Entry 10109             CDS       T01001                                  Symbol ARPC2, ARC34, PNAS-139, PRO2446, p34-Arc Name (RefSeq) actin related protein 2/3 complex subunit 2   KO K05758   actin related protein 2/3 complex, subunit 2 Organism hsa  Homo sapiens (human) Pathway hsa04144   Endocytosis hsa04530   Tight junction hsa04666   Fc gamma R-mediated phagocytosis hsa04810   Regulation of actin cytoskeleton hsa05100   Bacterial invasion of epithelial cells hsa05130   Pathogenic Escherichia coli infection hsa05131   Shigellosis hsa05132   Salmonella infection hsa05135   Yersinia infection Network nt06180  Pathogenic Escherichia coli nt06181  Salmonella nt06182  Shigella   Element N01066   ARNO-ARF-ACTB_G signaling pathway N01067   Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway N01078   EGF-EGFR-Actin signaling pathway N01079   Shigella IpaC to Actin signaling pathway N01086   Escherichia EspT to RAC signaling pathway N01092   Escherichia Eae/Tir to Actin signaling pathway N01094   Escherichia Eae/Tir/TccP to Actin signaling pathway N01096   Escherichia Map to CDC42 signaling pathway N01128   Salmonella SopE to RAC signaling pathway N01129   Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway N01287   Tight junction-Actin signaling pathway Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     10109 (ARPC2)   09144 Cellular community - eukaryotes    04530 Tight junction     10109 (ARPC2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     10109 (ARPC2)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     10109 (ARPC2)  09160 Human Diseases   09171 Infectious disease: bacterial    05130 Pathogenic Escherichia coli infection     10109 (ARPC2)    05132 Salmonella infection     10109 (ARPC2)    05131 Shigellosis     10109 (ARPC2)    05135 Yersinia infection     10109 (ARPC2)    05100 Bacterial invasion of epithelial cells     10109 (ARPC2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     10109 (ARPC2)   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:hsa04812]     10109 (ARPC2) Membrane trafficking [BR:hsa04131]  Others   Actin-binding proteins    Arp2/3 complex     10109 (ARPC2) Cytoskeleton proteins [BR:hsa04812]  Eukaryotic cytoskeleton proteins   Actin filaments / Microfilaments    Actin-binding proteins     Arp2/3 complex      10109 (ARPC2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  P34-Arc ARPC4 Motif Other DBs NCBI-GeneID:  10109 NCBI-ProteinID:  NP_005722 OMIM:  604224 HGNC:  705 Ensembl:  ENSG00000163466 UniProt:  O15144 Q53R19 Structure PDB LinkDB All DBs Position 2:218217189..218254348 Genome browser AA seq 300 aa AA seqDB search MILLEVNNRIIEETLALKFENAAAGNKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSIS LKFYKELQAHGADELLKRVYGSFLVNPESGYNVSLLYDLENLPASKDSIVHQAGMLKRNC FASVFEKYFQFQEEGKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKV FMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNASARDNT INLIHTFRDYLHYHIKCSKAYIHTRMRAKTSDFLKVLNRARPDAEKKEMKTITGKTFSSR NT seq 903 nt NT seq  +upstreamnt  +downstreamnt atgatcctgctggaggtgaacaaccgcatcatcgaggagacgctcgcgctcaagttcgag aacgcggccgccggaaacaaaccggaagcagtagaagtaacatttgcagatttcgatggg gtcctctatcatatttcaaatcctaatggagacaaaacaaaagtgatggtcagtatttct ttgaaattctacaaggaacttcaggcacatggtgctgatgagttattaaagagggtgtac gggagtttcttggtaaatccagaatcaggatacaatgtctctttgctatatgaccttgaa aatcttccggcatccaaggattccattgtgcatcaagctggcatgttgaagcgaaattgt tttgcctctgtctttgaaaaatacttccaattccaagaagagggcaaggaaggagagaac agggcagttatccattatagggatgatgagaccatgtatgttgagtctaaaaaggacaga gtcacagtagtcttcagcacagtgtttaaggatgacgacgatgtggtcattggaaaggtg ttcatgcaggagttcaaagaaggacgcagagccagccacacagccccacaggtcctcttt agccacagggaacctcctctggagctgaaagacacagacgccgctgtgggtgacaacatt ggctacattacctttgtgctgttccctcgtcacaccaatgccagtgctcgagacaacacc atcaacctgatccacacgttccgggactacctgcactaccacatcaagtgctctaaggcc tatattcacacacgtatgcgggcgaaaacgtctgacttcctcaaggtgctgaaccgcgca cgcccagatgccgagaaaaaagaaatgaaaacaatcacggggaagacgttttcatcccgc taa

Homo sapiens (human): 10094 Help Entry 10094             CDS       T01001                                  Symbol ARPC3, ARC21, p21-Arc Name (RefSeq) actin related protein 2/3 complex subunit 3   KO K05756   actin related protein 2/3 complex, subunit 3 Organism hsa  Homo sapiens (human) Pathway hsa04144   Endocytosis hsa04530   Tight junction hsa04666   Fc gamma R-mediated phagocytosis hsa04810   Regulation of actin cytoskeleton hsa05100   Bacterial invasion of epithelial cells hsa05130   Pathogenic Escherichia coli infection hsa05131   Shigellosis hsa05132   Salmonella infection hsa05135   Yersinia infection Network nt06180  Pathogenic Escherichia coli nt06181  Salmonella nt06182  Shigella   Element N01066   ARNO-ARF-ACTB_G signaling pathway N01067   Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway N01078   EGF-EGFR-Actin signaling pathway N01079   Shigella IpaC to Actin signaling pathway N01086   Escherichia EspT to RAC signaling pathway N01092   Escherichia Eae/Tir to Actin signaling pathway N01094   Escherichia Eae/Tir/TccP to Actin signaling pathway N01096   Escherichia Map to CDC42 signaling pathway N01128   Salmonella SopE to RAC signaling pathway N01129   Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway N01287   Tight junction-Actin signaling pathway Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     10094 (ARPC3)   09144 Cellular community - eukaryotes    04530 Tight junction     10094 (ARPC3)   09142 Cell motility    04810 Regulation of actin cytoskeleton     10094 (ARPC3)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     10094 (ARPC3)  09160 Human Diseases   09171 Infectious disease: bacterial    05130 Pathogenic Escherichia coli infection     10094 (ARPC3)    05132 Salmonella infection     10094 (ARPC3)    05131 Shigellosis     10094 (ARPC3)    05135 Yersinia infection     10094 (ARPC3)    05100 Bacterial invasion of epithelial cells     10094 (ARPC3)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     10094 (ARPC3)   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:hsa04812]     10094 (ARPC3) Membrane trafficking [BR:hsa04131]  Others   Actin-binding proteins    Arp2/3 complex     10094 (ARPC3) Cytoskeleton proteins [BR:hsa04812]  Eukaryotic cytoskeleton proteins   Actin filaments / Microfilaments    Actin-binding proteins     Arp2/3 complex      10094 (ARPC3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  P21-Arc Motif Other DBs NCBI-GeneID:  10094 NCBI-ProteinID:  NP_001265485 OMIM:  604225 HGNC:  706 Ensembl:  ENSG00000111229 UniProt:  O15145 Structure PDB LinkDB All DBs Position 12:complement(110434823..110450337) Genome browser AA seq 178 aa AA seqDB search MPAYHSSLMDPDTKLIGNMALLPIRSQFKGPAPRETKDTDIVDEAIYYFKANVFFKNYEI KNEADRTLIYITLYISECLKKLQKCNSKSQGEKEMYTLGITNFPIPGEPGFPLNAIYAKP ANKQEDEVMRAYLQQLRQETGLRLCEKVFDPQNDKPSKWWTCFVKRQFMNKSLSGPGQ NT seq 537 nt NT seq  +upstreamnt  +downstreamnt atgccggcttaccactcttctctcatggatcctgataccaaactcatcggaaacatggca ctgttgcctatcagaagtcaattcaaaggacctgcccccagagagacaaaagatacagat attgtggatgaagccatctattacttcaaggccaatgtcttcttcaaaaactatgaaatt aagaatgaagctgataggaccttgatatatataactctctacatttctgaatgtctgaag aaactgcaaaagtgcaattccaaaagccaaggtgagaaagaaatgtatacgctgggaatc actaattttcccattcctggagagcctggttttccacttaacgcaatttatgccaaacct gcaaacaaacaggaagatgaagtgatgagagcctatttacaacagctaaggcaagagact ggactgagactttgtgagaaagttttcgaccctcagaatgataaacccagcaagtggtgg acttgctttgtgaagagacagttcatgaacaagagtctttcaggacctggacagtga

Homo sapiens (human): 10093 Help Entry 10093             CDS       T01001                                  Symbol ARPC4, ARC20, DEVLO, P20-ARC Name (RefSeq) actin related protein 2/3 complex subunit 4   KO K05755   actin related protein 2/3 complex, subunit 4 Organism hsa  Homo sapiens (human) Pathway hsa04144   Endocytosis hsa04530   Tight junction hsa04666   Fc gamma R-mediated phagocytosis hsa04810   Regulation of actin cytoskeleton hsa05100   Bacterial invasion of epithelial cells hsa05130   Pathogenic Escherichia coli infection hsa05131   Shigellosis hsa05132   Salmonella infection hsa05135   Yersinia infection Network nt06180  Pathogenic Escherichia coli nt06181  Salmonella nt06182  Shigella   Element N01066   ARNO-ARF-ACTB_G signaling pathway N01067   Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway N01078   EGF-EGFR-Actin signaling pathway N01079   Shigella IpaC to Actin signaling pathway N01086   Escherichia EspT to RAC signaling pathway N01092   Escherichia Eae/Tir to Actin signaling pathway N01094   Escherichia Eae/Tir/TccP to Actin signaling pathway N01096   Escherichia Map to CDC42 signaling pathway N01128   Salmonella SopE to RAC signaling pathway N01129   Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway N01287   Tight junction-Actin signaling pathway Disease H02685   Developmental delay with neuropsychiatric disorders Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     10093 (ARPC4)   09144 Cellular community - eukaryotes    04530 Tight junction     10093 (ARPC4)   09142 Cell motility    04810 Regulation of actin cytoskeleton     10093 (ARPC4)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     10093 (ARPC4)  09160 Human Diseases   09171 Infectious disease: bacterial    05130 Pathogenic Escherichia coli infection     10093 (ARPC4)    05132 Salmonella infection     10093 (ARPC4)    05131 Shigellosis     10093 (ARPC4)    05135 Yersinia infection     10093 (ARPC4)    05100 Bacterial invasion of epithelial cells     10093 (ARPC4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     10093 (ARPC4)   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:hsa04812]     10093 (ARPC4) Membrane trafficking [BR:hsa04131]  Others   Actin-binding proteins    Arp2/3 complex     10093 (ARPC4) Cytoskeleton proteins [BR:hsa04812]  Eukaryotic cytoskeleton proteins   Actin filaments / Microfilaments    Actin-binding proteins     Arp2/3 complex      10093 (ARPC4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  ARPC4 Sm_like Cmr7A DurN Motif Other DBs NCBI-GeneID:  10093 NCBI-ProteinID:  NP_005709 OMIM:  604226 HGNC:  707 Ensembl:  ENSG00000241553 UniProt:  P59998 Structure PDB LinkDB All DBs Position 3:9792518..9807101 Genome browser AA seq 168 aa AA seqDB search MTATLRPYLSAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVTISRNEKEK VLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITN FHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF NT seq 507 nt NT seq  +upstreamnt  +downstreamnt atgactgccactctccgcccctacctgagtgccgtgcgggccacattgcaggctgccctc tgcctggagaacttctcctcccaggttgtggaacgacacaacaagccggaagtggaagtc aggagtagcaaagagctcctgttacaacctgtgaccatcagcaggaatgagaaggaaaag gttctgattgagggctccatcaactctgtccgggtcagcattgctgtgaaacaggctgat gagatcgagaagattttgtgccacaagttcatgcgcttcatgatgatgcgagcagagaac ttctttatccttcgaaggaagcctgtggaggggtatgatatcagctttctgatcaccaac ttccacacagagcagatgtacaaacacaagttggtggactttgtgatccacttcatggag gagattgacaaggagatcagtgagatgaagctgtcagtcaatgcccgtgcccgcattgtg gctgaagagttccttaagaatttttaa

Homo sapiens (human): 10092 Help Entry 10092             CDS       T01001                                  Symbol ARPC5, ARC16, IMD113, dJ127C7.3, p16-Arc Name (RefSeq) actin related protein 2/3 complex subunit 5   KO K05754   actin related protein 2/3 complex, subunit 5 Organism hsa  Homo sapiens (human) Pathway hsa04144   Endocytosis hsa04530   Tight junction hsa04666   Fc gamma R-mediated phagocytosis hsa04810   Regulation of actin cytoskeleton hsa05100   Bacterial invasion of epithelial cells hsa05130   Pathogenic Escherichia coli infection hsa05131   Shigellosis hsa05132   Salmonella infection hsa05135   Yersinia infection Network nt06180  Pathogenic Escherichia coli nt06181  Salmonella nt06182  Shigella   Element N01066   ARNO-ARF-ACTB_G signaling pathway N01067   Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway N01078   EGF-EGFR-Actin signaling pathway N01079   Shigella IpaC to Actin signaling pathway N01086   Escherichia EspT to RAC signaling pathway N01092   Escherichia Eae/Tir to Actin signaling pathway N01094   Escherichia Eae/Tir/TccP to Actin signaling pathway N01096   Escherichia Map to CDC42 signaling pathway N01128   Salmonella SopE to RAC signaling pathway N01129   Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway N01287   Tight junction-Actin signaling pathway Disease H01725   Primary immunodeficiency disease Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     10092 (ARPC5)   09144 Cellular community - eukaryotes    04530 Tight junction     10092 (ARPC5)   09142 Cell motility    04810 Regulation of actin cytoskeleton     10092 (ARPC5)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     10092 (ARPC5)  09160 Human Diseases   09171 Infectious disease: bacterial    05130 Pathogenic Escherichia coli infection     10092 (ARPC5)    05132 Salmonella infection     10092 (ARPC5)    05131 Shigellosis     10092 (ARPC5)    05135 Yersinia infection     10092 (ARPC5)    05100 Bacterial invasion of epithelial cells     10092 (ARPC5)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     10092 (ARPC5)   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:hsa04812]     10092 (ARPC5) Membrane trafficking [BR:hsa04131]  Others   Actin-binding proteins    Arp2/3 complex     10092 (ARPC5) Cytoskeleton proteins [BR:hsa04812]  Eukaryotic cytoskeleton proteins   Actin filaments / Microfilaments    Actin-binding proteins     Arp2/3 complex      10092 (ARPC5) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  P16-Arc Utp12 UTP15_C Glyoxalase_4 Motif Other DBs NCBI-GeneID:  10092 NCBI-ProteinID:  NP_005708 OMIM:  604227 HGNC:  708 Ensembl:  ENSG00000162704 UniProt:  O15511 Structure PDB LinkDB All DBs Position 1:complement(183620846..183635783) Genome browser AA seq 151 aa AA seqDB search MSKNTVSSARFRKVDVDEYDENKFVDEEDGGDGQAGPDEGEVDSCLRQGNMTAALQAALK NPPINTKSQAVKDRAGSIVLKVLISFKANDIEKAVQSLDKNGVDLLMKYIYKGFESPSDN SSAMLLQWHEKALAAGGVGSIVRVLTARKTV NT seq 456 nt NT seq  +upstreamnt  +downstreamnt atgtcgaagaacacagtgtcgtcggcccgcttccggaaggtggacgtggatgaatatgac gagaacaagttcgtggacgaagaagatgggggcgacggccaggccgggcccgacgagggc gaggtggactcctgcctgcggcaaggaaacatgacagctgccctacaggcagctctgaag aacccccctatcaacaccaagagtcaggcagtgaaggaccgggcaggcagcattgtcttg aaggtgctcatctcttttaaagctaatgatatagaaaaggcagttcaatctctggacaag aatggtgtggatctcctaatgaagtatatttataaaggatttgagagcccgtctgacaat agcagtgctatgttactgcaatggcatgaaaaggcacttgctgctggaggagtagggtcc attgttcgtgtcttgactgcaagaaaaactgtgtag

Homo sapiens (human): 81873 Help Entry 81873             CDS       T01001                                  Symbol ARPC5L, ARC16-2 Name (RefSeq) actin related protein 2/3 complex subunit 5 like   KO K05754   actin related protein 2/3 complex, subunit 5 Organism hsa  Homo sapiens (human) Pathway hsa04144   Endocytosis hsa04530   Tight junction hsa04666   Fc gamma R-mediated phagocytosis hsa04810   Regulation of actin cytoskeleton hsa05100   Bacterial invasion of epithelial cells hsa05130   Pathogenic Escherichia coli infection hsa05131   Shigellosis hsa05132   Salmonella infection hsa05135   Yersinia infection Network nt06180  Pathogenic Escherichia coli nt06181  Salmonella nt06182  Shigella   Element N01066   ARNO-ARF-ACTB_G signaling pathway N01067   Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway N01078   EGF-EGFR-Actin signaling pathway N01079   Shigella IpaC to Actin signaling pathway N01086   Escherichia EspT to RAC signaling pathway N01092   Escherichia Eae/Tir to Actin signaling pathway N01094   Escherichia Eae/Tir/TccP to Actin signaling pathway N01096   Escherichia Map to CDC42 signaling pathway N01128   Salmonella SopE to RAC signaling pathway N01129   Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway N01287   Tight junction-Actin signaling pathway Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     81873 (ARPC5L)   09144 Cellular community - eukaryotes    04530 Tight junction     81873 (ARPC5L)   09142 Cell motility    04810 Regulation of actin cytoskeleton     81873 (ARPC5L)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     81873 (ARPC5L)  09160 Human Diseases   09171 Infectious disease: bacterial    05130 Pathogenic Escherichia coli infection     81873 (ARPC5L)    05132 Salmonella infection     81873 (ARPC5L)    05131 Shigellosis     81873 (ARPC5L)    05135 Yersinia infection     81873 (ARPC5L)    05100 Bacterial invasion of epithelial cells     81873 (ARPC5L)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     81873 (ARPC5L)   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:hsa04812]     81873 (ARPC5L) Membrane trafficking [BR:hsa04131]  Others   Actin-binding proteins    Arp2/3 complex     81873 (ARPC5L) Cytoskeleton proteins [BR:hsa04812]  Eukaryotic cytoskeleton proteins   Actin filaments / Microfilaments    Actin-binding proteins     Arp2/3 complex      81873 (ARPC5L) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  P16-Arc Utp12 Utp13 Motif Other DBs NCBI-GeneID:  81873 NCBI-ProteinID:  NP_112240 HGNC:  23366 Ensembl:  ENSG00000136950 UniProt:  Q9BPX5 A0A024R897 B3KPC7 Structure PDB LinkDB All DBs Position 9:124862130..124877733 Genome browser AA seq 153 aa AA seqDB search MARNTLSSRFRRVDIDEFDENKFVDEQEEAAAAAAEPGPDPSEVDGLLRQGDMLRAFHAA LRNSPVNTKNQAVKERAQGVVLKVLTNFKSSEIEQAVQSLDRNGVDLLMKYIYKGFEKPT ENSSAVLLQWHEKALAVGGLGSIIRVLTARKTV NT seq 462 nt NT seq  +upstreamnt  +downstreamnt atggcccggaacacgctgtcctcgcgcttccgccgggtggacatcgacgaatttgacgag aacaaatttgtggacgagcaggaggaggcggcggcggcggcggcggagccaggcccggac ccgagcgaggtggacgggctcctgcggcaaggggacatgcttcgggcattccatgcagcc ttgcggaactctcccgtcaacaccaagaatcaagctgtgaaggagcgagcccagggcgtg gtgctgaaagtgctcacaaacttcaagagcagtgagattgagcaggctgtgcagtcactg gacagaaacggcgttgacttgttaatgaagtacatttataaaggctttgagaagcccaca gaaaatagcagcgcagtgttactccagtggcacgaaaaggccttagcagtaggaggacta ggctccattataagagttcttacagcaagaaagactgtttaa

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