Homo sapiens (human): 10454
Help
Entry
10454 CDS
T01001
Symbol
TAB1, 3'-Tab1, MAP3K7IP1
Name
(RefSeq) TGF-beta activated kinase 1 (MAP3K7) binding protein 1
KO
K04403
TAK1-binding protein 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04010
MAPK signaling pathway
hsa04064
NF-kappa B signaling pathway
hsa04380
Osteoclast differentiation
hsa04620
Toll-like receptor signaling pathway
hsa04621
NOD-like receptor signaling pathway
hsa04668
TNF signaling pathway
hsa04936
Alcoholic liver disease
hsa05130
Pathogenic Escherichia coli infection
hsa05131
Shigellosis
hsa05132
Salmonella infection
hsa05135
Yersinia infection
hsa05140
Leishmaniasis
hsa05145
Toxoplasmosis
hsa05161
Hepatitis B
hsa05168
Herpes simplex virus 1 infection
hsa05169
Epstein-Barr virus infection
hsa05170
Human immunodeficiency virus 1 infection
hsa05417
Lipid and atherosclerosis
Network
nt06160
Human T-cell leukemia virus 1 (HTLV-1)
nt06161
Human immunodeficiency virus 1 (HIV-1)
nt06163
Hepatitis C virus (HCV)
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165
Epstein-Barr virus (EBV)
nt06167
Human cytomegalovirus (HCMV)
nt06180
Pathogenic Escherichia coli
nt06181
Salmonella
nt06182
Shigella
nt06211
Other MAPK signaling (cancer)
nt06223
TNF signaling (cancer)
nt06263
Hepatocellular carcinoma
nt06461
Huntington disease
nt06516
TNF signaling
nt06517
TLR signaling
nt06526
MAPK signaling
Element
N00151
TNF-NFKB signaling pathway
N00186
IL1-IL1R-p38 signaling pathway
N00188
IL1-IL1R-JNK signaling pathway
N00265
EBV LMP1 to NFKB signaling pathway
N00441
HIV gp120 to TNF-NFKB signaling pathway
N00442
HIV Nef to TNF-NFKB signaling pathway
N00444
TNF-p38 signaling pathway
N00446
TNF-JNK signaling pathway
N00466
EBV BPLF1 to TLR2/4-NFKB signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
10454 (TAB1)
04064 NF-kappa B signaling pathway
10454 (TAB1)
04668 TNF signaling pathway
10454 (TAB1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
10454 (TAB1)
04621 NOD-like receptor signaling pathway
10454 (TAB1)
09158 Development and regeneration
04380 Osteoclast differentiation
10454 (TAB1)
09160 Human Diseases
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
10454 (TAB1)
05161 Hepatitis B
10454 (TAB1)
05168 Herpes simplex virus 1 infection
10454 (TAB1)
05169 Epstein-Barr virus infection
10454 (TAB1)
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection
10454 (TAB1)
05132 Salmonella infection
10454 (TAB1)
05131 Shigellosis
10454 (TAB1)
05135 Yersinia infection
10454 (TAB1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
10454 (TAB1)
05140 Leishmaniasis
10454 (TAB1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
10454 (TAB1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
10454 (TAB1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PP2C
PA14
Lzipper-MIP1
Motif
Other DBs
NCBI-GeneID:
10454
NCBI-ProteinID:
NP_006107
OMIM:
602615
HGNC:
18157
Ensembl:
ENSG00000100324
Pharos:
Q15750
(Tbio)
UniProt:
Q15750
A8K6K3
Structure
PDB
PDBj
LinkDB
All DBs
Position
22:39399780..39437132
Genome browser
AA seq
504 aa
AA seq
DB search
MAAQRRSLLQSEQQPSWTDDLPLCHLSGVGSASNRSYSADGKGTESHPPEDSWLKFRSEN
NCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNAEHAEADVRRVLLQAFDVVERSFLES
IDDALAEKASLQSQLPEGVPQHQLPPQYQKILERLKTLEREISGGAMAVVAVLLNNKLYV
ANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQEST
RRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAH
GPGQANQEIAAMIDTEFAKQTSLDAVAQAVVDRVKRIHSDTFASGGERARFCPRHEDMTL
LVRNFGYPLGEMSQPTPSPAPAAGGRVYPVSVPYSSAQSTSKTSVTLSLVMPSQGQMVNG
AHSASTLDEATPTLTNQSPTLTLQSTNTHTQSSSSSSDGGLFRSRPAHSLPPGEDGRVEP
YVDFAEFYRLWSVDHGEQSVVTAP
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgcagaggaggagcttgctgcagagtgagcagcagccaagctggacagatgac
ctgcctctctgccacctctctggggttggctcagcctccaaccgcagctactctgctgat
ggcaagggcactgagagccacccgccagaggacagctggctcaagttcaggagtgagaac
aactgcttcctgtatggggtcttcaacggctatgatggcaaccgagtgaccaacttcgtg
gcccagcggctgtccgcagagctcctgctgggccagctgaatgccgagcacgccgaggcc
gatgtgcggcgtgtgctgctgcaggccttcgatgtggtggagaggagcttcctggagtcc
attgacgacgccttggctgagaaggcaagcctccagtcgcaattgccagagggagtccct
cagcaccagctgcctcctcagtatcagaagatccttgagagactcaagacgttagagagg
gaaatttcgggaggggccatggccgttgtggcggtccttctcaacaacaagctctacgtc
gccaatgtcggtacaaaccgtgcacttttatgcaaatcgacagtggatgggttgcaggtg
acacagctgaacgtggaccacaccacagagaacgaggatgagctcttccgtctttcgcag
ctgggcttggatgctggaaagatcaagcaggtggggatcatctgtgggcaggagagcacc
cggcggatcggggattacaaggttaaatatggctacacggacattgaccttctcagcgct
gccaagtccaaaccaatcatcgcagagccagaaatccatggggcacagccgctggatggg
gtgacgggcttcttggtgctgatgtcggaggggttgtacaaggccctagaggcagcccat
gggcctgggcaggccaaccaggagattgctgcgatgattgacactgagtttgccaagcag
acctccctggacgcagtggcccaggccgtcgtggaccgggtgaagcgcatccacagcgac
accttcgccagtggtggggagcgtgccaggttctgcccccggcacgaggacatgaccctg
ctagtgaggaactttggctacccgctgggcgaaatgagccagcccacaccgagcccagcc
ccagctgcaggaggacgagtgtaccctgtgtctgtgccatactccagcgcccagagcacc
agcaagaccagcgtgaccctctcccttgtcatgccctcccagggccagatggtcaacggg
gctcacagtgcttccaccctggacgaagccacccccaccctcaccaaccaaagcccgacc
ttaaccctgcagtccaccaacacgcacacgcagagcagcagctccagctctgacggaggc
ctcttccgctcccggcccgcccactcgctcccgcctggcgaggacggtcgtgttgagccc
tatgtggactttgctgagttttaccgcctctggagcgtggaccatggcgagcagagcgtg
gtgacagcaccgtag
Homo sapiens (human): 23118
Help
Entry
23118 CDS
T01001
Symbol
TAB2, CHTD2, MAP3K7IP2, TAB-2
Name
(RefSeq) TGF-beta activated kinase 1 (MAP3K7) binding protein 2
KO
K04404
TAK1-binding protein 2
Organism
hsa
Homo sapiens (human)
Pathway
hsa04010
MAPK signaling pathway
hsa04064
NF-kappa B signaling pathway
hsa04380
Osteoclast differentiation
hsa04620
Toll-like receptor signaling pathway
hsa04621
NOD-like receptor signaling pathway
hsa04657
IL-17 signaling pathway
hsa04668
TNF signaling pathway
hsa04936
Alcoholic liver disease
hsa05130
Pathogenic Escherichia coli infection
hsa05131
Shigellosis
hsa05132
Salmonella infection
hsa05135
Yersinia infection
hsa05140
Leishmaniasis
hsa05145
Toxoplasmosis
hsa05161
Hepatitis B
hsa05162
Measles
hsa05168
Herpes simplex virus 1 infection
hsa05169
Epstein-Barr virus infection
hsa05170
Human immunodeficiency virus 1 infection
hsa05171
Coronavirus disease - COVID-19
hsa05417
Lipid and atherosclerosis
Network
nt06160
Human T-cell leukemia virus 1 (HTLV-1)
nt06161
Human immunodeficiency virus 1 (HIV-1)
nt06162
Hepatitis B virus (HBV)
nt06163
Hepatitis C virus (HCV)
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165
Epstein-Barr virus (EBV)
nt06167
Human cytomegalovirus (HCMV)
nt06168
Herpes simplex virus 1 (HSV-1)
nt06169
Measles virus (MV)
nt06180
Pathogenic Escherichia coli
nt06181
Salmonella
nt06182
Shigella
nt06183
Yersinia
nt06211
Other MAPK signaling (cancer)
nt06223
TNF signaling (cancer)
nt06263
Hepatocellular carcinoma
nt06461
Huntington disease
nt06516
TNF signaling
nt06517
TLR signaling
nt06526
MAPK signaling
Element
N00151
TNF-NFKB signaling pathway
N00186
IL1-IL1R-p38 signaling pathway
N00188
IL1-IL1R-JNK signaling pathway
N00265
EBV LMP1 to NFKB signaling pathway
N00435
TLR1/2/4-NFKB signaling pathway
N00438
TLR2/4-MAPK signaling pathway
N00441
HIV gp120 to TNF-NFKB signaling pathway
N00442
HIV Nef to TNF-NFKB signaling pathway
N00444
TNF-p38 signaling pathway
N00446
TNF-JNK signaling pathway
N00466
EBV BPLF1 to TLR2/4-NFKB signaling pathway
N00562
HSV US3 to TLR2/4-NFKB signaling pathway
N00692
MV P to TLR2/4-NFKB signaling pathway
N00859
Yersinia YopP/J to TLR2/4-NFKB signaling pathway
N00926
Escherichia Tir to TLR2/4-MAPK signaling pathway
N00927
Escherichia/Shigella NleE/OspZ to TNF-NFKB signaling pathway
N01566
TLR5-NFKB signaling pathway
N01797
EDA-EDAR signaling pathway
Disease
H02199
Congenital heart defects, multiple type
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
23118 (TAB2)
04064 NF-kappa B signaling pathway
23118 (TAB2)
04668 TNF signaling pathway
23118 (TAB2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
23118 (TAB2)
04621 NOD-like receptor signaling pathway
23118 (TAB2)
04657 IL-17 signaling pathway
23118 (TAB2)
09158 Development and regeneration
04380 Osteoclast differentiation
23118 (TAB2)
09160 Human Diseases
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
23118 (TAB2)
05161 Hepatitis B
23118 (TAB2)
05171 Coronavirus disease - COVID-19
23118 (TAB2)
05162 Measles
23118 (TAB2)
05168 Herpes simplex virus 1 infection
23118 (TAB2)
05169 Epstein-Barr virus infection
23118 (TAB2)
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection
23118 (TAB2)
05132 Salmonella infection
23118 (TAB2)
05131 Shigellosis
23118 (TAB2)
05135 Yersinia infection
23118 (TAB2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
23118 (TAB2)
05140 Leishmaniasis
23118 (TAB2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
23118 (TAB2)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
23118 (TAB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
CUE
zf-RanBP
Sos7
HIP1_clath_bdg
DivIC
Motif
Other DBs
NCBI-GeneID:
23118
NCBI-ProteinID:
NP_001278963
OMIM:
605101
HGNC:
17075
Ensembl:
ENSG00000055208
Pharos:
Q9NYJ8
(Tbio)
UniProt:
Q9NYJ8
Structure
PDB
PDBj
LinkDB
All DBs
Position
6:149217926..149411607
Genome browser
AA seq
693 aa
AA seq
DB search
MAQGSHQIDFQVLHDLRQKFPEVPEVVVSRCMLQNNNNLDACCAVLSQESTRYLYGEGDL
NFSDDSGISGLRNHMTSLNLDLQSQNIYHHGREGSRMNGSRTLTHSISDGQLQGGQSNSE
LFQQEPQTAPAQVPQGFNVFGMSSSSGASNSAPHLGFHLGSKGTSSLSQQTPRFNPIMVT
LAPNIQTGRNTPTSLHIHGVPPPVLNSPQGNSIYIRPYITTPGGTTRQTQQHSGWVSQFN
PMNPQQVYQPSQPGPWTTCPASNPLSHTSSQQPNQQGHQTSHVYMPISSPTTSQPPTIHS
SGSSQSSAHSQYNIQNISTGPRKNQIEIKLEPPQRNNSSKLRSSGPRTSSTSSSVNSQTL
NRNQPTVYIAASPPNTDELMSRSQPKVYISANAATGDEQVMRNQPTLFISTNSGASAASR
NMSGQVSMGPAFIHHHPPKSRAIGNNSATSPRVVVTQPNTKYTFKITVSPNKPPAVSPGV
VSPTFELTNLLNHPDHYVETENIQHLTDPTLAHVDRISETRKLSMGSDDAAYTQALLVHQ
KARMERLQRELEIQKKKLDKLKSEVNEMENNLTRRRLKRSNSISQIPSLEEMQQLRSCNR
QLQIDIDCLTKEIDLFQARGPHFNPSAIHNFYDNIGFVGPVPPKPKDQRSIIKTPKTQDT
EDDEGAQWNCTACTFLNHPALIRCEQCEMPRHF
NT seq
2082 nt
NT seq
+upstream
nt +downstream
nt
atggcccaaggaagccaccaaattgattttcaggttttacatgacctgcgacaaaaattc
cctgaagtacctgaagttgttgtatccaggtgcatgttacagaataataataacctggat
gcctgctgtgctgttctctctcaggagagtacaagatatctttatggtgaaggagacttg
aatttttcagatgattctggaatttctggtctacgcaatcacatgacttctctcaacttg
gacttgcaatcacagaacatttaccaccatggaagagaaggaagtaggatgaatggaagt
aggactctaacgcacagcattagtgatggacaacttcaaggtggccagtccaatagtgaa
ctatttcagcaggagccacagacagcaccagctcaagttcctcaaggctttaatgttttt
ggaatgtccagttcctctggtgcttcaaattcagcaccacatcttggatttcacttaggc
agcaaaggaacatctagcctttctcaacaaactcccagatttaatcccattatggtaact
ttagccccaaatatccagactggtcgtaatactcctacatctttgcacatacatggtgta
cctccacctgtacttaacagtccacagggaaattctatctatattaggccttacattaca
actcctggtggtacaactcgacagacacaacagcattctggctgggtatctcagtttaat
cccatgaaccctcagcaagtttatcagccttcacagcctggtccctggactacttgtcct
gcatctaatcctctgtcacatacctcatctcaacagccaaatcagcaaggccaccagacc
tctcatgtctacatgccaatcagttcacctactacttcacaaccaccaaccattcattca
tctggtagctcacagtcttctgcccatagccaatataacattcagaatatttcaacagga
cctcgaaaaaaccagattgaaatcaaacttgaacccccacaaagaaataattcttcaaaa
ctgcgttcttctggacctcgaacctccagcacttcctcttcagtcaatagccagacctta
aacagaaatcagcccactgtttacatagctgccagccccccaaatacggatgagctgatg
tcccgtagtcaacctaaggtctatatttcagcgaatgctgccacaggagatgaacaggtc
atgcggaatcagcccacactcttcatatccacaaactctggagcatctgctgcctccagg
aacatgtctgggcaagtgagcatgggtcctgcctttattcatcaccatcctcccaaaagt
cgagcaataggcaataactctgcaacctctcctcgagtggtagtcactcagcccaatacg
aaatacactttcaaaattacagtctctcccaataagccccctgcagtttcaccaggggtg
gtgtcccctacctttgaacttacaaatcttcttaatcatcctgatcattatgtagaaacc
gagaatattcagcacctcacggaccctacattagcacatgtggatagaataagtgaaaca
cggaaactgagtatgggatctgatgatgctgcctacacacaagctcttttggtacaccag
aaggccagaatggaacgacttcaaagagaacttgagattcaaaagaaaaagctggataaa
ttaaaatctgaggttaatgaaatggaaaataatctaactcgaaggcgcctgaaaagatca
aattctatatcccagataccttcccttgaagaaatgcagcagctgagaagttgtaataga
caactccagattgacattgactgcttaaccaaagaaattgatctttttcaagcccgagga
ccacattttaaccccagcgctattcataacttttatgacaatattggatttgtaggtcct
gtgccaccaaaacccaaagatcaaaggtccatcatcaaaacaccaaagactcaagacaca
gaagatgatgagggagctcagtggaattgtaccgcctgtacttttttgaaccatccagcc
ttaattcgctgtgaacagtgtgagatgccaaggcatttctga
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integrated database retrieval system
