KEGG   Homo sapiens (human): 2932
Entry
2932              CDS       T01001                                 

Gene name
GSK3B
Definition
(RefSeq) glycogen synthase kinase 3 beta
  KO
K03083  glycogen synthase kinase 3 beta [EC:2.7.11.26]
Organism
hsa  Homo sapiens (human)
Pathway
hsa01521  EGFR tyrosine kinase inhibitor resistance
hsa04012  ErbB signaling pathway
hsa04062  Chemokine signaling pathway
hsa04110  Cell cycle
hsa04150  mTOR signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04310  Wnt signaling pathway
hsa04340  Hedgehog signaling pathway
hsa04360  Axon guidance
hsa04390  Hippo signaling pathway
hsa04510  Focal adhesion
hsa04550  Signaling pathways regulating pluripotency of stem cells
hsa04657  IL-17 signaling pathway
hsa04660  T cell receptor signaling pathway
hsa04662  B cell receptor signaling pathway
hsa04722  Neurotrophin signaling pathway
hsa04728  Dopaminergic synapse
hsa04910  Insulin signaling pathway
hsa04916  Melanogenesis
hsa04917  Prolactin signaling pathway
hsa04919  Thyroid hormone signaling pathway
hsa04931  Insulin resistance
hsa04932  Non-alcoholic fatty liver disease
hsa04934  Cushing syndrome
hsa04935  Growth hormone synthesis, secretion and action
hsa05010  Alzheimer disease
hsa05020  Prion disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05131  Shigellosis
hsa05135  Yersinia infection
hsa05160  Hepatitis C
hsa05162  Measles
hsa05163  Human cytomegalovirus infection
hsa05165  Human papillomavirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05200  Pathways in cancer
hsa05210  Colorectal cancer
hsa05213  Endometrial cancer
hsa05215  Prostate cancer
hsa05217  Basal cell carcinoma
hsa05224  Breast cancer
hsa05225  Hepatocellular carcinoma
hsa05226  Gastric cancer
hsa05415  Diabetic cardiomyopathy
hsa05417  Lipid and atherosclerosis
Network
nt06114  PI3K signaling (viruses)
nt06115  WNT signaling (viruses and bacteria)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06169  Measles virus (MV)
nt06215  WNT signaling
nt06260  Colorectal cancer
nt06261  Gastric cancer
nt06263  Hepatocellular carcinoma
nt06270  Breast cancer
nt06271  Endometrial cancer
nt06274  Thyroid cancer
nt06419  Microtubule-based transport
nt06460  Alzheimer disease
nt06465  Prion disease
  Element
N00056  Wnt signaling pathway
N00057  Mutation-inactivated APC to Wnt signaling pathway
N00058  Mutation-activated CTNNB1 to Wnt signaling pathway
N00059  FZD7-overexpression to Wnt signaling pathway
N00060  LRP6-overexpression to Wnt signaling pathway
N00175  KSHV LANA to Wnt signaling pathway
N00242  Mutation-inactivated AXIN to Wnt signaling pathway
N00683  CD80/CD86-CD28-PI3K signaling pathway
N01017  Mutation-caused aberrant PSEN1 to anterograde axonal transport
N01202  Oligomeric conformation PrPc to anterograde axonal transport
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    2932 (GSK3B)
   04310 Wnt signaling pathway
    2932 (GSK3B)
   04340 Hedgehog signaling pathway
    2932 (GSK3B)
   04390 Hippo signaling pathway
    2932 (GSK3B)
   04151 PI3K-Akt signaling pathway
    2932 (GSK3B)
   04150 mTOR signaling pathway
    2932 (GSK3B)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    2932 (GSK3B)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    2932 (GSK3B)
   04550 Signaling pathways regulating pluripotency of stem cells
    2932 (GSK3B)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    2932 (GSK3B)
   04657 IL-17 signaling pathway
    2932 (GSK3B)
   04662 B cell receptor signaling pathway
    2932 (GSK3B)
   04062 Chemokine signaling pathway
    2932 (GSK3B)
  09152 Endocrine system
   04910 Insulin signaling pathway
    2932 (GSK3B)
   04917 Prolactin signaling pathway
    2932 (GSK3B)
   04935 Growth hormone synthesis, secretion and action
    2932 (GSK3B)
   04919 Thyroid hormone signaling pathway
    2932 (GSK3B)
   04916 Melanogenesis
    2932 (GSK3B)
  09156 Nervous system
   04728 Dopaminergic synapse
    2932 (GSK3B)
   04722 Neurotrophin signaling pathway
    2932 (GSK3B)
  09158 Development and regeneration
   04360 Axon guidance
    2932 (GSK3B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    2932 (GSK3B)
  09162 Cancer: specific types
   05210 Colorectal cancer
    2932 (GSK3B)
   05225 Hepatocellular carcinoma
    2932 (GSK3B)
   05226 Gastric cancer
    2932 (GSK3B)
   05217 Basal cell carcinoma
    2932 (GSK3B)
   05215 Prostate cancer
    2932 (GSK3B)
   05213 Endometrial cancer
    2932 (GSK3B)
   05224 Breast cancer
    2932 (GSK3B)
  09172 Infectious disease: viral
   05160 Hepatitis C
    2932 (GSK3B)
   05162 Measles
    2932 (GSK3B)
   05163 Human cytomegalovirus infection
    2932 (GSK3B)
   05167 Kaposi sarcoma-associated herpesvirus infection
    2932 (GSK3B)
   05165 Human papillomavirus infection
    2932 (GSK3B)
  09171 Infectious disease: bacterial
   05131 Shigellosis
    2932 (GSK3B)
   05135 Yersinia infection
    2932 (GSK3B)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    2932 (GSK3B)
   05020 Prion disease
    2932 (GSK3B)
   05022 Pathways of neurodegeneration - multiple diseases
    2932 (GSK3B)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    2932 (GSK3B)
   05415 Diabetic cardiomyopathy
    2932 (GSK3B)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    2932 (GSK3B)
   04931 Insulin resistance
    2932 (GSK3B)
   04934 Cushing syndrome
    2932 (GSK3B)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    2932 (GSK3B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    2932 (GSK3B)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    2932 (GSK3B)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.26  tau-protein kinase
     2932 (GSK3B)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CMGC group
  GSK family [OT]
   2932 (GSK3B)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation and ciliogenesis proteins
   Kinases and associated factors
    2932 (GSK3B)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like APH Kdo ABC1
Other DBs
NCBI-GeneID: 2932
NCBI-ProteinID: NP_001139628
OMIM: 605004
HGNC: 4617
Ensembl: ENSG00000082701
Vega: OTTHUMG00000133765
Pharos: P49841(Tclin)
UniProt: P49841 Q6FI27
LinkDB
Structure
PDB: 

Position
3q13.33
AA seq 420 aa
MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTK
VIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSG
EKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHR
DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDV
WSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHP
WTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALF
NFTTQELSSNPPLATILIPPHARIQAAASTPTNATAASDANTGDRGQTNNAASASASNST
NT seq 1263 nt   +upstreamnt  +downstreamnt
atgtcagggcggcccagaaccacctcctttgcggagagctgcaagccggtgcagcagcct
tcagcttttggcagcatgaaagttagcagagacaaggacggcagcaaggtgacaacagtg
gtggcaactcctgggcagggtccagacaggccacaagaagtcagctatacagacactaaa
gtgattggaaatggatcatttggtgtggtatatcaagccaaactttgtgattcaggagaa
ctggtcgccatcaagaaagtattgcaggacaagagatttaagaatcgagagctccagatc
atgagaaagctagatcactgtaacatagtccgattgcgttatttcttctactccagtggt
gagaagaaagatgaggtctatcttaatctggtgctggactatgttccggaaacagtatac
agagttgccagacactatagtcgagccaaacagacgctccctgtgatttatgtcaagttg
tatatgtatcagctgttccgaagtttagcctatatccattcctttggaatctgccatcgg
gatattaaaccgcagaacctcttgttggatcctgatactgctgtattaaaactctgtgac
tttggaagtgcaaagcagctggtccgaggagaacccaatgtttcgtatatctgttctcgg
tactatagggcaccagagttgatctttggagccactgattatacctctagtatagatgta
tggtctgctggctgtgtgttggctgagctgttactaggacaaccaatatttccaggggat
agtggtgtggatcagttggtagaaataatcaaggtcctgggaactccaacaagggagcaa
atcagagaaatgaacccaaactacacagaatttaaattccctcaaattaaggcacatcct
tggactaaggtcttccgaccccgaactccaccggaggcaattgcactgtgtagccgtctg
ctggagtatacaccaactgcccgactaacaccactggaagcttgtgcacattcatttttt
gatgaattacgggacccaaatgtcaaactaccaaatgggcgagacacacctgcactcttc
aacttcaccactcaagaactgtcaagtaatccacctctggctaccatccttattcctcct
catgctcggattcaagcagctgcttcaacccccacaaatgccacagcagcgtcagatgct
aatactggagaccgtggacagaccaataatgctgcttctgcatcagcttccaactccacc
tga

KEGG   Homo sapiens (human): 1457
Entry
1457              CDS       T01001                                 

Gene name
CSNK2A1, CK2A1, CKII, Cka1, Cka2, OCNDS
Definition
(RefSeq) casein kinase 2 alpha 1
  KO
K03097  casein kinase II subunit alpha [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03008  Ribosome biogenesis in eukaryotes
hsa04064  NF-kappa B signaling pathway
hsa04137  Mitophagy - animal
hsa04310  Wnt signaling pathway
hsa04520  Adherens junction
hsa05010  Alzheimer disease
hsa05020  Prion disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05162  Measles
hsa05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Network
nt06419  Microtubule-based transport
nt06465  Prion disease
  Element
N01202  Oligomeric conformation PrPc to anterograde axonal transport
Disease
H02459  Syndromic neurodevelopmental disorder
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03008 Ribosome biogenesis in eukaryotes
    1457 (CSNK2A1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    1457 (CSNK2A1)
   04064 NF-kappa B signaling pathway
    1457 (CSNK2A1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    1457 (CSNK2A1)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    1457 (CSNK2A1)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    1457 (CSNK2A1)
  09172 Infectious disease: viral
   05162 Measles
    1457 (CSNK2A1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    1457 (CSNK2A1)
   05020 Prion disease
    1457 (CSNK2A1)
   05022 Pathways of neurodegeneration - multiple diseases
    1457 (CSNK2A1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    1457 (CSNK2A1)
  09182 Protein families: genetic information processing
   03009 Ribosome biogenesis [BR:hsa03009]
    1457 (CSNK2A1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     1457 (CSNK2A1)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: Other
  CK2 family
   1457 (CSNK2A1)
Ribosome biogenesis [BR:hsa03009]
 Eukaryotic type
  90S particles
   Kinase
    1457 (CSNK2A1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Pkinase_fungal Kdo Choline_kinase ABC1 FTA2
Other DBs
NCBI-GeneID: 1457
NCBI-ProteinID: NP_001886
OMIM: 115440
HGNC: 2457
Ensembl: ENSG00000101266
Vega: OTTHUMG00000031636
Pharos: P68400(Tchem)
UniProt: P68400
LinkDB
Structure
PDB: 
3WAR 5ZN1 5ZN0 5ZN2 5CVG 4KWP 3NSZ 5OUL 5CU6 5OTQ 5MOH 5CSV 6EHK 6Q4Q 5OTZ 6FVF 5OTY 6HOT 5ZN3 5CSP 3BQC 5OTO 5OTR 5M4F 5OYF 6HOP 6HOQ 5OS8 5CU4 3H30 5OTL 5OTP 5OTD 5OSR 6HBN 5OTI 5CSH 6FVG 3AT2 3PE1 2PVR 5OT5 5OSU 5CVF 5N9K 6HNY 5ZN4 3MB7 6GMD 5OS7 3JUH 6A1C 5CLP 5OTH 5ZN5 3Q9W 5CU2 5CX9 6Q38 5ORH 3R0T 3MB6 6JWA 5N9L 5CU3 6HOR 6HOU 3Q9Y 3Q04 3OWK 5OUU 5MO8 5MO6 5N9N 6HME 5CVH 4RLL 3OWJ 5MOW 5CS6 5MOE 5OTS 3PE2 5OSP 5MP8 6EII 5OT6 5M4C 6EHU 5OSL 5OMY 3C13 6GIH 5ORJ 5MMF 6HNW 5OSZ 5ONI 5NQC 5MMR 5H8G 3WIK 5OUE 5CT0 5CTP 5MO5 5OUM 5MOD 5MOT 4UB7 3OWL 5T1H 5KWH 5ORK 5MPJ 5MO7 5H8E 4GRB 5CU0 5MOV 4IB5 4GUB 3U4U 3Q9X 3Q9Z 3AT4 5M4I 5KU8 5OWL 5OWH 5B0X 3RPS 3AMY 3FWQ 5OQU 4FBX 5CQU 3W8L 2ZJW 1NA7 3WOW 3AXW 3QA0 1PJK 5N1V 5H8B 3AT3 5CQW 5M44 3NGA 3WIL 3U87 4UBA 4DGL 4MD7 1JWH 3U9C 4NH1 4MD8 4MD9

Position
20p13
AA seq 391 aa
MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINIT
NNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTD
FKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE
FYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYD
QLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDF
LDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPT
PSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ
NT seq 1176 nt   +upstreamnt  +downstreamnt
atgtcgggacccgtgccaagcagggccagagtttacacagatgttaatacacacagacct
cgagaatactgggattacgagtcacatgtggtggaatggggaaatcaagatgactaccag
ctggttcgaaaattaggccgaggtaaatacagtgaagtatttgaagccatcaacatcaca
aataatgaaaaagttgttgttaaaattctcaagccagtaaaaaagaagaaaattaagcgt
gaaataaagattttggagaatttgagaggaggtcccaacatcatcacactggcagacatt
gtaaaagaccctgtgtcacgaacccccgccttggtttttgaacacgtaaacaacacagac
ttcaagcaattgtaccagacgttaacagactatgatattcgattttacatgtatgagatt
ctgaaggccctggattattgtcacagcatgggaattatgcacagagatgtcaagccccat
aatgtcatgattgatcatgagcacagaaagctacgactaatagactggggtttggctgag
ttttatcatcctggccaagaatataatgtccgagttgcttcccgatacttcaaaggtcct
gagctacttgtagactatcagatgtacgattatagtttggatatgtggagtttgggttgt
atgctggcaagtatgatctttcggaaggagccatttttccatggacatgacaattatgat
cagttggtgaggatagccaaggttctggggacagaagatttatatgactatattgacaaa
tacaacattgaattagatccacgtttcaatgatatcttgggcagacactctcgaaagcga
tgggaacgctttgtccacagtgaaaatcagcaccttgtcagccctgaggccttggatttc
ctggacaaactgctgcgatatgaccaccagtcacggcttactgcaagagaggcaatggag
cacccctatttctacactgttgtgaaggaccaggctcgaatgggttcatctagcatgcca
gggggcagtacgcccgtcagcagcgccaatatgatgtcagggatttcttcagtgccaacc
ccttcaccccttggacctctggcaggctcaccagtgattgctgctgccaacccccttggg
atgcctgttccagctgccgctggcgctcagcagtaa

KEGG   Homo sapiens (human): 1459
Entry
1459              CDS       T01001                                 

Gene name
CSNK2A2, CK2A2, CK2alpha', CSNK2A1
Definition
(RefSeq) casein kinase 2 alpha 2
  KO
K03097  casein kinase II subunit alpha [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03008  Ribosome biogenesis in eukaryotes
hsa04064  NF-kappa B signaling pathway
hsa04137  Mitophagy - animal
hsa04310  Wnt signaling pathway
hsa04520  Adherens junction
hsa05010  Alzheimer disease
hsa05020  Prion disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05162  Measles
hsa05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Network
nt06419  Microtubule-based transport
nt06465  Prion disease
  Element
N01202  Oligomeric conformation PrPc to anterograde axonal transport
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03008 Ribosome biogenesis in eukaryotes
    1459 (CSNK2A2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    1459 (CSNK2A2)
   04064 NF-kappa B signaling pathway
    1459 (CSNK2A2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    1459 (CSNK2A2)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    1459 (CSNK2A2)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    1459 (CSNK2A2)
  09172 Infectious disease: viral
   05162 Measles
    1459 (CSNK2A2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    1459 (CSNK2A2)
   05020 Prion disease
    1459 (CSNK2A2)
   05022 Pathways of neurodegeneration - multiple diseases
    1459 (CSNK2A2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    1459 (CSNK2A2)
  09182 Protein families: genetic information processing
   03009 Ribosome biogenesis [BR:hsa03009]
    1459 (CSNK2A2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     1459 (CSNK2A2)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: Other
  CK2 family
   1459 (CSNK2A2)
Ribosome biogenesis [BR:hsa03009]
 Eukaryotic type
  90S particles
   Kinase
    1459 (CSNK2A2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Pkinase_fungal Kdo Choline_kinase ABC1
Other DBs
NCBI-GeneID: 1459
NCBI-ProteinID: NP_001887
OMIM: 115442
HGNC: 2459
Ensembl: ENSG00000070770
Vega: OTTHUMG00000133488
Pharos: P19784(Tchem)
UniProt: P19784
LinkDB
Structure
PDB: 

Position
16q21
AA seq 350 aa
MPGPAAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINI
TNNERVVVKILKPVKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNT
DFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLA
EFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNY
DQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALD
LLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCADNAVLSSGLTAAR
NT seq 1053 nt   +upstreamnt  +downstreamnt
atgcccggcccggccgcgggcagcagggcccgggtctacgccgaggtgaacagtctgagg
agccgcgagtactgggactacgaggctcacgtcccgagctggggtaatcaagatgattac
caactggttcgaaaacttggtcggggaaaatatagtgaagtatttgaggccattaatatc
accaacaatgagagagtggttgtaaaaatcctgaagccagtgaagaaaaagaagataaaa
cgagaggttaagattctggagaaccttcgtggtggaacaaatatcattaagctgattgac
actgtaaaggaccccgtgtcaaagacaccagctttggtatttgaatatatcaataataca
gattttaagcaactctaccagatcctgacagactttgatatccggttttatatgtatgaa
ctacttaaagctctggattactgccacagcaagggaatcatgcacagggatgtgaaacct
cacaatgtcatgatagatcaccaacagaaaaagctgcgactgatagattggggtctggca
gaattctatcatcctgctcaggagtacaatgttcgtgtagcctcaaggtacttcaaggga
ccagagctcctcgtggactatcagatgtatgattatagcttggacatgtggagtttgggc
tgtatgttagcaagcatgatctttcgaagggaaccattcttccatggacaggacaactat
gaccagcttgttcgcattgccaaggttctgggtacagaagaactgtatgggtatctgaag
aagtatcacatagacctagatccacacttcaacgatatcctgggacaacattcacggaaa
cgctgggaaaactttatccatagtgagaacagacaccttgtcagccctgaggccctagat
cttctggacaaacttctgcgatacgaccatcaacagagactgactgccaaagaggccatg
gagcacccatacttctaccctgtggtgaaggagcagtcccagccttgtgcagacaatgct
gtgctttccagtggtctcacggcagcacgatga

KEGG   Homo sapiens (human): 1460
Entry
1460              CDS       T01001                                 

Gene name
CSNK2B, CK2B, CK2N, CSK2B, Ckb1, Ckb2, G5A, POBINDS
Definition
(RefSeq) casein kinase 2 beta
  KO
K03115  casein kinase II subunit beta
Organism
hsa  Homo sapiens (human)
Pathway
hsa03008  Ribosome biogenesis in eukaryotes
hsa04064  NF-kappa B signaling pathway
hsa04137  Mitophagy - animal
hsa04310  Wnt signaling pathway
hsa04520  Adherens junction
hsa05010  Alzheimer disease
hsa05020  Prion disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05162  Measles
hsa05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Network
nt06419  Microtubule-based transport
nt06465  Prion disease
  Element
N01202  Oligomeric conformation PrPc to anterograde axonal transport
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03008 Ribosome biogenesis in eukaryotes
    1460 (CSNK2B)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    1460 (CSNK2B)
   04064 NF-kappa B signaling pathway
    1460 (CSNK2B)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    1460 (CSNK2B)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    1460 (CSNK2B)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    1460 (CSNK2B)
  09172 Infectious disease: viral
   05162 Measles
    1460 (CSNK2B)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    1460 (CSNK2B)
   05020 Prion disease
    1460 (CSNK2B)
   05022 Pathways of neurodegeneration - multiple diseases
    1460 (CSNK2B)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03009 Ribosome biogenesis [BR:hsa03009]
    1460 (CSNK2B)
   03036 Chromosome and associated proteins [BR:hsa03036]
    1460 (CSNK2B)
Ribosome biogenesis [BR:hsa03009]
 Eukaryotic type
  90S particles
   Kinase
    1460 (CSNK2B)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   Polycomb group proteins
    AUTS2-polycomb complex
     1460 (CSNK2B)
SSDB
Motif
Pfam: CK_II_beta CCDC24
Other DBs
NCBI-GeneID: 1460
NCBI-ProteinID: NP_001311
OMIM: 115441
HGNC: 2460
Ensembl: ENSG00000204435
Vega: OTTHUMG00000177888
Pharos: P67870(Tbio)
UniProt: P67870 N0E4C7
LinkDB
Structure
PDB: 

Position
6p21.33
AA seq 215 aa
MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDE
ELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPML
PIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPA
NQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR
NT seq 648 nt   +upstreamnt  +downstreamnt
atgagcagctcagaggaggtgtcctggatttcctggttctgtgggctccgtggcaatgaa
ttcttctgtgaagtggatgaagactacatccaggacaaatttaatcttactggactcaat
gagcaggtccctcactatcgacaagctctagacatgatcttggacctggagcctgatgaa
gaactggaagacaaccccaaccagagtgacctgattgagcaggcagccgagatgctttat
ggattgatccacgcccgctacatccttaccaaccgtggcatcgcccagatgttggaaaag
taccagcaaggagactttggttactgtcctcgtgtgtactgtgagaaccagccaatgctt
cccattggcctttcagacatcccaggtgaagccatggtgaagctctactgccccaagtgc
atggatgtgtacacacccaagtcatcaagacaccatcacacggatggcgcctacttcggc
actggtttccctcacatgctcttcatggtgcatcccgagtaccggcccaagagacctgcc
aaccagtttgtgcccaggctctacggtttcaagatccatccgatggcctaccagctgcag
ctccaagccgccagcaacttcaagagcccagtcaagacgattcgctga

KEGG   Homo sapiens (human): 283106
Entry
283106            CDS       T01001                                 

Gene name
CSNK2A3, CSNK2A1P
Definition
(RefSeq) casein kinase 2 alpha 3
  KO
K03097  casein kinase II subunit alpha [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03008  Ribosome biogenesis in eukaryotes
hsa04064  NF-kappa B signaling pathway
hsa04137  Mitophagy - animal
hsa04310  Wnt signaling pathway
hsa04520  Adherens junction
hsa05010  Alzheimer disease
hsa05020  Prion disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05162  Measles
hsa05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Network
nt06419  Microtubule-based transport
nt06465  Prion disease
  Element
N01202  Oligomeric conformation PrPc to anterograde axonal transport
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03008 Ribosome biogenesis in eukaryotes
    283106 (CSNK2A3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    283106 (CSNK2A3)
   04064 NF-kappa B signaling pathway
    283106 (CSNK2A3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    283106 (CSNK2A3)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    283106 (CSNK2A3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    283106 (CSNK2A3)
  09172 Infectious disease: viral
   05162 Measles
    283106 (CSNK2A3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    283106 (CSNK2A3)
   05020 Prion disease
    283106 (CSNK2A3)
   05022 Pathways of neurodegeneration - multiple diseases
    283106 (CSNK2A3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    283106 (CSNK2A3)
  09182 Protein families: genetic information processing
   03009 Ribosome biogenesis [BR:hsa03009]
    283106 (CSNK2A3)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     283106 (CSNK2A3)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: Other
  CK2 family
   283106 (CSNK2A3)
Ribosome biogenesis [BR:hsa03009]
 Eukaryotic type
  90S particles
   Kinase
    283106 (CSNK2A3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Pkinase_fungal Kdo Choline_kinase ABC1 FTA2
Other DBs
NCBI-GeneID: 283106
NCBI-ProteinID: NP_001243615
HGNC: 2458
Ensembl: ENSG00000254598
Vega: OTTHUMG00000165708
Pharos: Q8NEV1(Tdark)
UniProt: Q8NEV1
LinkDB
Position
11p15.4
AA seq 391 aa
MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINIT
NNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTD
FKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE
FYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWRLGCMLASMIFRKEPFFHGRDNYD
QLVRIAKFLGTEDLYGYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDF
LDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANVMSGISSVPT
PSPLGPLAGSPVIAAANPLGMPVPAATGAQQ
NT seq 1176 nt   +upstreamnt  +downstreamnt
atgtcgggacccgtgccaagcagggccagagtttacacagatgttaatacacacagacct
cgagaatactgggattacgagtcacatgtggtggaatggggaaatcaagatgactaccag
ctggttcgaaaattaggccgaggtaaatacagtgaagtatttgaagccatcaacatcaca
aataatgaaaaagttgttgttaaaattctcaagccagtaaaaaagaagaaaattaagcgt
gaaataaagattttggagaatttgagaggaggtcccaacatcatcacactggcagacatt
gtaaaagaccctgtgtcacgaacccccgccttggtttttgaacacgtaaacaacacagac
ttcaagcaattgtaccagacgttaacagactatgatattcgattttacatgtatgagatt
ctgaaggccctggattattgtcacagcatgggaattatgcacagagatgtcaagccccat
aatgtcatgattgatcatgagcacagaaagctacgactaatagactggggtttggctgag
ttttatcatcctggccaagaatataatgtccgagttgcttcccgatacttcaaaggtcct
gagctacttgtagactatcagatgtacgattatagtttggatatgtggagattgggttgt
atgctggcaagtatgatctttcggaaggagccatttttccatggacgtgacaattatgat
cagttggtgaggatagccaagtttctggggacagaagatttatatggctatattgacaaa
tacaacattgaattagatccacgtttcaatgatatcttgggcagacactctcgaaagcga
tgggaacgctttgtccacagtgaaaatcagcaccttgtcagccctgaggccttggatttc
ctggacaaactgctgcgatatgaccaccagtcacggcttactgcaagagaggccatggag
cacccctatttctacactgttgtgaaggaccaggctcgaatgggttcatctagcatgcca
gggggcagtacgcccgtcagcagcgccaatgtgatgtcagggatttcttcagtgccaact
ccttcaccccttggacctctggcaggctcaccagtgattgctgctgccaacccccttggg
atgcctgttccagctgccactggcgctcagcagtaa

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