KEGG   Homo sapiens (human): 3760
Entry
3760              CDS       T01001                                 
Symbol
KCNJ3, GIRK1, KGA, KIR3.1
Name
(RefSeq) potassium inwardly rectifying channel subfamily J member 3
  KO
K04997  potassium inwardly-rectifying channel subfamily J member 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04713  Circadian entrainment
hsa04723  Retrograde endocannabinoid signaling
hsa04724  Glutamatergic synapse
hsa04725  Cholinergic synapse
hsa04726  Serotonergic synapse
hsa04728  Dopaminergic synapse
hsa04915  Estrogen signaling pathway
hsa04921  Oxytocin signaling pathway
hsa04929  GnRH secretion
hsa05032  Morphine addiction
Network
nt06544  Neuroactive ligand signaling
  Element
N01889  Gbeta/gamma-KCNJ signaling
Drug target
Amiodarone (DG00204): D00636<JP/US> D02910
Bepridil (DG00333): D00631<JP> D07520
Dronedarone (DG00207): D02537 D03914<US>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04929 GnRH secretion
    3760 (KCNJ3)
   04915 Estrogen signaling pathway
    3760 (KCNJ3)
   04921 Oxytocin signaling pathway
    3760 (KCNJ3)
  09156 Nervous system
   04724 Glutamatergic synapse
    3760 (KCNJ3)
   04725 Cholinergic synapse
    3760 (KCNJ3)
   04728 Dopaminergic synapse
    3760 (KCNJ3)
   04726 Serotonergic synapse
    3760 (KCNJ3)
   04723 Retrograde endocannabinoid signaling
    3760 (KCNJ3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    3760 (KCNJ3)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    3760 (KCNJ3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    3760 (KCNJ3)
Ion channels [BR:hsa04040]
 Voltage-gated cation channels
  Potassium channel, inwardly-rectifying (Kir)
   3760 (KCNJ3)
SSDB
Motif
Pfam: IRK_C IRK
Other DBs
NCBI-GeneID: 3760
NCBI-ProteinID: NP_002230
OMIM: 601534
HGNC: 6264
Ensembl: ENSG00000162989
UniProt: P48549
LinkDB
Position
2:154698695..154858354
AA seq 501 aa
MSALRRKFGDDYQVVTTSSSGSGLQPQGPGQDPQQQLVPKKKRQRFVDKNGRCNVQHGNL
GSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNY
TPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCM
FIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPE
GEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILE
GIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSVKE
QEEMLLMSSPLIAPAITNSKERHNSVECLDGLDDITTKLPSKLQKITGREDFPKKLLRMS
STTSEKAYSLGDLPMKLQRISSVPGNSEEKLVSKTTKMLSDPMSQSVADLPPKLQKMAGG
AARMEGNLPAKLRKMNSDRFT
NT seq 1506 nt   +upstreamnt  +downstreamnt
atgtctgcactccgaaggaaatttggggacgattatcaggtagtgaccacatcgtccagc
ggctcgggcttgcagccccaggggccaggccaggaccctcagcagcagcttgtgcccaag
aagaagcggcagcggttcgtggacaagaacggccggtgcaatgtacagcacggcaacctg
ggcagcgagacaagccgctacctctcggacctcttcaccacgctggtggacctcaagtgg
cgctggaacctcttcatcttcattctcacctacaccgtggcctggcttttcatggcgtcc
atgtggtgggtgatcgcctacactcggggcgacctgaacaaagcccacgtcggtaactac
acgccttgcgtggccaatgtctataacttcccttctgccttcctcttcttcatcgagacg
gaggccaccatcggctatggctaccgatacatcacagacaagtgccccgagggcatcatc
ctcttcctcttccagtccatcctgggctccatcgtggacgccttcctcatcggctgcatg
ttcatcaagatgtcccagcccaagaagcgcgccgagaccctcatgttcagcgagcacgcg
gtgatctccatgagggacggaaaactcacgcttatgttccgggtgggcaacctgcgcaac
agccacatggtctccgcgcagattcgctgcaagctgctcaaatctcggcagacacctgag
ggtgagttccttccccttgaccaacttgaactggatgtaggttttagtacaggggcagat
caactttttcttgtgtcccccctcacaatttgccacgtgatcgatgccaaaagccccttt
tatgacctatcccagcgaagcatgcaaactgaacagttcgagattgtcgtcatcctagaa
ggcattgtggaaacaactgggatgacttgtcaagctcgaacatcatatactgaagatgaa
gttctttggggtcatcgtttttttcctgtaatttccttagaagagggattctttaaagtt
gattactcccagttccatgcaacatttgaagtccccaccccaccttacagtgtgaaagag
caggaggaaatgcttctcatgtcgtcccctttaatagcaccagccataactaacagcaaa
gaaagacataattctgtggaatgcttagatggactagatgatattactacaaaactacca
tctaagctgcagaaaattactggaagagaagactttcccaaaaaactcttgaggatgagt
tctacaacttcagaaaaagcctacagcttgggagacttgcccatgaaacttcaacgaata
agttcagttccgggcaactcagaagaaaaactggtatctaaaaccaccaagatgttatct
gatcccatgagccagtctgtggctgatttgccaccaaagcttcaaaagatggctggagga
gcagctaggatggaagggaaccttccagccaaattaagaaaaatgaactctgatcgcttc
acataa

KEGG   Homo sapiens (human): 3762
Entry
3762              CDS       T01001                                 
Symbol
KCNJ5, CIR, GIRK4, KATP1, KIR3.4, LQT13
Name
(RefSeq) potassium inwardly rectifying channel subfamily J member 5
  KO
K04999  potassium inwardly-rectifying channel subfamily J member 5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04713  Circadian entrainment
hsa04723  Retrograde endocannabinoid signaling
hsa04726  Serotonergic synapse
hsa04728  Dopaminergic synapse
hsa04915  Estrogen signaling pathway
hsa04921  Oxytocin signaling pathway
hsa04925  Aldosterone synthesis and secretion
hsa04929  GnRH secretion
hsa05032  Morphine addiction
Network
nt06316  Renin-angiotensin-aldosterone signaling
nt06544  Neuroactive ligand signaling
  Element
N00303  Mutation-activated KCNJ5 to angiotensin-aldosterone signaling pathway
N01889  Gbeta/gamma-KCNJ signaling
Disease
H00720  Long QT syndrome
H01603  Primary aldosteronism
Drug target
Amiodarone (DG00204): D00636<JP/US> D02910
Bepridil (DG00333): D00631<JP> D07520
Dronedarone (DG00207): D02537 D03914<US>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04929 GnRH secretion
    3762 (KCNJ5)
   04915 Estrogen signaling pathway
    3762 (KCNJ5)
   04921 Oxytocin signaling pathway
    3762 (KCNJ5)
   04925 Aldosterone synthesis and secretion
    3762 (KCNJ5)
  09156 Nervous system
   04728 Dopaminergic synapse
    3762 (KCNJ5)
   04726 Serotonergic synapse
    3762 (KCNJ5)
   04723 Retrograde endocannabinoid signaling
    3762 (KCNJ5)
  09159 Environmental adaptation
   04713 Circadian entrainment
    3762 (KCNJ5)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    3762 (KCNJ5)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    3762 (KCNJ5)
Ion channels [BR:hsa04040]
 Voltage-gated cation channels
  Potassium channel, inwardly-rectifying (Kir)
   3762 (KCNJ5)
SSDB
Motif
Pfam: IRK_C IRK Ion_trans_2
Other DBs
NCBI-GeneID: 3762
NCBI-ProteinID: NP_000881
OMIM: 600734
HGNC: 6266
Ensembl: ENSG00000120457
UniProt: P48544 A0A5J6E2W8
LinkDB
Position
11:128891356..128921163
AA seq 419 aa
MAGDSRNAMNQDMEIGVTPWDPKKIPKQARDYVPIATDRTRLLAEGKKPRQRYMEKSGKC
NVHHGNVQETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIWWLIAYIRGDLDH
VGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIILLLVQAILGSIVNA
FMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLRNSHIVEASIRAKLIK
SRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKSPFWEMSQAQLHQEEFE
VVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYEVDYNTFHDTYETNTP
SCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEEDEPKGLGGSREARGSV
NT seq 1260 nt   +upstreamnt  +downstreamnt
atggctggcgattctaggaatgccatgaaccaggacatggagattggagtcactccctgg
gaccccaagaagattccaaaacaggcccgcgattatgtccccattgccacagaccgtacg
cgcctgctggccgagggcaagaagccacgccagcgctacatggagaagagtggcaagtgc
aacgtgcaccacggcaacgtccaggagacctaccggtacctgagtgacctcttcaccacc
ctggtggacctcaagtggcgcttcaacttgctcgtcttcaccatggtttacactgtcacc
tggctgttcttcggcttcatttggtggctcattgcttatatccggggtgacctggaccat
gttggcgaccaagagtggattccttgtgttgaaaacctcagtggcttcgtgtccgctttc
ctgttctccattgagaccgaaacaaccattgggtatggcttccgagtcatcacagagaag
tgtccagaggggattatactcctcttggtccaggccatcctgggctccatcgtcaatgcc
ttcatggtggggtgcatgtttgtcaagatcagccagcccaagaagagagcggagaccctc
atgttttccaacaacgcagtcatctccatgcgggacgagaagctgtgcctcatgttccgg
gtgggcgacctccgcaactcccacatcgtggaggcctccatccgggccaagctcatcaag
tcccggcagaccaaagagggggagttcatccccctgaaccagacagacatcaacgtgggc
tttgacacgggcgacgaccgcctcttccttgtgtctcctctgatcatctcccatgagatc
aaccagaagagccctttctgggagatgtctcaggctcagctgcatcaggaagagtttgaa
gttgtggtcattctagaagggatggtggaagccacaggcatgacctgccaagcccggagc
tcctacatggatacagaggtgctctggggccaccgattcacaccagtcctcaccttggaa
aagggcttctatgaggtggactacaacaccttccatgatacctatgagaccaacacaccc
agctgctgtgccaaggagctggcagaaatgaagagggaaggccggctcctccagtacctc
cccagccccccactgctggggggctgtgctgaggcagggctggatgcagaggctgagcag
aatgaagaagatgagcccaaggggctgggtgggtccagggaggccaggggctcggtgtga

KEGG   Homo sapiens (human): 3763
Entry
3763              CDS       T01001                                 
Symbol
KCNJ6, BIR1, GIRK-2, GIRK2, KATP-2, KATP2, KCNJ7, KIR3.2, KPLBS, hiGIRK2
Name
(RefSeq) potassium inwardly rectifying channel subfamily J member 6
  KO
K05000  potassium inwardly-rectifying channel subfamily J member 6
Organism
hsa  Homo sapiens (human)
Pathway
hsa04713  Circadian entrainment
hsa04723  Retrograde endocannabinoid signaling
hsa04725  Cholinergic synapse
hsa04726  Serotonergic synapse
hsa04727  GABAergic synapse
hsa04728  Dopaminergic synapse
hsa04915  Estrogen signaling pathway
hsa04921  Oxytocin signaling pathway
hsa04929  GnRH secretion
hsa05032  Morphine addiction
Network
nt06544  Neuroactive ligand signaling
  Element
N01889  Gbeta/gamma-KCNJ signaling
Disease
H02236  Keppen-Lubinsky syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04929 GnRH secretion
    3763 (KCNJ6)
   04915 Estrogen signaling pathway
    3763 (KCNJ6)
   04921 Oxytocin signaling pathway
    3763 (KCNJ6)
  09156 Nervous system
   04727 GABAergic synapse
    3763 (KCNJ6)
   04725 Cholinergic synapse
    3763 (KCNJ6)
   04728 Dopaminergic synapse
    3763 (KCNJ6)
   04726 Serotonergic synapse
    3763 (KCNJ6)
   04723 Retrograde endocannabinoid signaling
    3763 (KCNJ6)
  09159 Environmental adaptation
   04713 Circadian entrainment
    3763 (KCNJ6)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    3763 (KCNJ6)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    3763 (KCNJ6)
Ion channels [BR:hsa04040]
 Voltage-gated cation channels
  Potassium channel, inwardly-rectifying (Kir)
   3763 (KCNJ6)
SSDB
Motif
Pfam: IRK_C IRK
Other DBs
NCBI-GeneID: 3763
NCBI-ProteinID: NP_002231
OMIM: 600877
HGNC: 6267
Ensembl: ENSG00000157542
UniProt: P48051
LinkDB
Position
21:complement(37607373..37916457)
AA seq 423 aa
MAKLTESMTNVLEGDSMDQDVESPVAIHQPKLPKQARDDLPRHISRDRTKRKIQRYVRKD
GKCNVHHGNVRETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWWLIAYIRGD
MDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGIILLLIQSVLGSI
VNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRNSHIVEASIRAK
LIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPFWEISKAQLPKE
ELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYEVDYNSFHETYET
STPSLSAKELAELASRAELPLSWSVSSKLNQHAELETEEEEKNLEEQTERNGDVANLENE
SKV
NT seq 1272 nt   +upstreamnt  +downstreamnt
atggccaagctgacagaatccatgactaacgtcctggagggcgactccatggatcaggac
gtcgaaagcccagtggccattcaccagccaaagttgcctaagcaggccagggatgacctg
ccaagacacatcagccgagatcggaccaaaaggaaaatccagaggtacgtgaggaaagac
ggaaagtgcaatgttcatcacggcaacgtgagggagacctatcgctacctgaccgatatc
ttcaccacattagtggacctgaagtggagattcaacctattgatttttgtcatggtttac
acagtgacctggctcttttttggaatgatctggtggttgatcgcatacatacggggagac
atggaccacatagaggacccctcctggactccttgtgttaccaacctcaacgggttcgtc
tctgcttttttattctcaatagagacagaaaccaccattggttatggctaccgggtcatc
acagataaatgcccagagggaattattcttctcttaatccaatctgtgttggggtccatt
gtcaatgcattcatggtgggatgcatgtttgtaaaaatctctcaacccaagaagagggca
gagaccctggtcttttccacccatgcagtgatctccatgcgggatgggaaactgtgcctg
atgttccgggtaggggaccttaggaattcccacattgtggaggcttccatcagagccaag
ttgatcaaatccaaacagacctcggagggggagttcatcccgttgaaccagacggatatc
aacgtagggtattacacgggggatgaccgtctgtttctggtgtcaccgctgatcattagc
catgaaattaaccaacagagtcctttctgggagatctccaaagcccagctgcccaaagag
gaactggaaattgtggtcatcctagaaggaatggtggaagccacagggatgacatgccaa
gctcgaagctcctacatcaccagtgagatcctgtggggttaccggttcacacctgtcctg
accctggaggacgggttctacgaagttgactacaacagcttccatgagacctatgagacc
agcaccccatcccttagtgccaaagagctggccgagttagccagcagggcagagctgccc
ctgagttggtctgtatccagcaaactcaaccaacatgcagaactggagactgaagaggaa
gaaaagaacctcgaagagcaaacagaaagaaatggtgatgtggcaaacctggagaatgaa
tccaaagtttag

KEGG   Homo sapiens (human): 3765
Entry
3765              CDS       T01001                                 
Symbol
KCNJ9, GIRK3, KIR3.3
Name
(RefSeq) potassium inwardly rectifying channel subfamily J member 9
  KO
K05002  potassium inwardly-rectifying channel subfamily J member 9
Organism
hsa  Homo sapiens (human)
Pathway
hsa04713  Circadian entrainment
hsa04723  Retrograde endocannabinoid signaling
hsa04726  Serotonergic synapse
hsa04728  Dopaminergic synapse
hsa04915  Estrogen signaling pathway
hsa04921  Oxytocin signaling pathway
hsa04929  GnRH secretion
hsa05032  Morphine addiction
Network
nt06544  Neuroactive ligand signaling
  Element
N01889  Gbeta/gamma-KCNJ signaling
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04929 GnRH secretion
    3765 (KCNJ9)
   04915 Estrogen signaling pathway
    3765 (KCNJ9)
   04921 Oxytocin signaling pathway
    3765 (KCNJ9)
  09156 Nervous system
   04728 Dopaminergic synapse
    3765 (KCNJ9)
   04726 Serotonergic synapse
    3765 (KCNJ9)
   04723 Retrograde endocannabinoid signaling
    3765 (KCNJ9)
  09159 Environmental adaptation
   04713 Circadian entrainment
    3765 (KCNJ9)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    3765 (KCNJ9)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    3765 (KCNJ9)
Ion channels [BR:hsa04040]
 Voltage-gated cation channels
  Potassium channel, inwardly-rectifying (Kir)
   3765 (KCNJ9)
SSDB
Motif
Pfam: IRK_C IRK Ion_trans_2 Ion_trans
Other DBs
NCBI-GeneID: 3765
NCBI-ProteinID: NP_004974
OMIM: 600932
HGNC: 6270
Ensembl: ENSG00000162728
UniProt: Q92806
Structure
LinkDB
Position
1:160081538..160090563
AA seq 393 aa
MAQENAAFSPGQEEPPRRRGRQRYVEKDGRCNVQQGNVRETYRYLTDLFTTLVDLQWRLS
LLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETT
IGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVS
LRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLF
LVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLW
GHRFTSVLTLEDGFYEVDYASFHETFEVPTPSCSARELAEAAARLDAHLYWSIPSRLDEK
VEEEGAGEGAGGEAGADKEQNGCLPPPESESKV
NT seq 1182 nt   +upstreamnt  +downstreamnt
atggcgcaggagaacgcggccttctcgcccgggcaggaggagccgccgcggcgccgcggc
cgccagcgctacgtggagaaggatggccggtgcaacgtgcagcagggcaacgtgcgcgag
acataccgctacctgacggacctgttcaccacgctggtggacctgcagtggcgcctcagc
ctgttgttcttcgtcctggcctacgcgctcacctggctcttcttcggcgccatctggtgg
ctgatcgcctacggccgcggcgacctggagcacctggaggacaccgcgtggacgccgtgc
gtcaacaacctcaacggcttcgtggccgccttcctcttctccatcgagaccgagaccacc
atcggctacgggcaccgcgtcatcaccgaccagtgccccgagggcatcgtgctgctgctg
ctgcaggccatcctgggctccatggtgaacgccttcatggtgggctgcatgttcgtcaag
atctcgcagcccaacaagcgcgcagccacgctcgtcttctcctcgcacgccgtggtgtcg
ctgcgcgacgggcgcctctgcctcatgttccgcgtgggcgacttgcgctcctcacacata
gtggaggcctccatccgcgccaagctcatccgctcgcgccagacgctggagggcgagttc
atcccgctgcaccagaccgacctcagcgtgggcttcgacacgggagacgaccgcctcttc
ctcgtctcgccgctggttatcagccacgagatcgacgccgccagccccttctgggaggcg
tcgcgccgtgccctcgagagggacgacttcgagatcgtcgttatcctcgagggcatggtg
gaagccacgggaatgacatgccaagctcggagctcctacctggtagacgaggtgctgtgg
ggccaccgcttcacgtcagtgctgactctggaggacggcttctacgaagtggactatgcc
agctttcacgagacttttgaggtgcccacaccttcgtgcagtgctcgagagctggcagag
gctgccgcccgccttgatgcccatctctactggtccatccccagccggctggatgagaag
gtggaggaggagggggcgggggagggggcgggtggggaagctggggctgacaaggagcag
aatggctgcctgccacccccagagagtgagtccaaggtgtga

KEGG   Homo sapiens (human): 3767
Entry
3767              CDS       T01001                                 
Symbol
KCNJ11, BIR, HHF2, IKATP, KIR6.2, MODY13, PHHI, PNDM2, TNDM3
Name
(RefSeq) potassium inwardly rectifying channel subfamily J member 11
  KO
K05004  potassium inwardly-rectifying channel subfamily J member 11
Organism
hsa  Homo sapiens (human)
Pathway
hsa04911  Insulin secretion
hsa04929  GnRH secretion
hsa04930  Type II diabetes mellitus
Disease
H00409  Type 2 diabetes mellitus
H00410  Maturity onset diabetes of the young (MODY)
H00512  Permanent neonatal diabetes mellitus
H00513  Transient neonatal diabetes mellitus
H01267  Familial hyperinsulinemic hypoglycemia
Drug target
Amiodarone (DG00204): D00636<JP/US> D02910
Bepridil (DG00333): D00631<JP> D07520
Chlorpropamide: D00271
Diazoxide: D00294<JP/US>
Diazoxide (DG03325): D12987<US>
Dronedarone (DG00207): D03914<US>
Glibenclamide: D00336<JP/US>
Glymidine: D01356
Levcromakalim: D02385 D02385
Linogliride (DG02893): D04739 D04740
Minoxidil: D00418<US>
Mitiglinide: D01854<JP>
Naminidil: D05114 D05114
Nateglinide: D01111<JP/US>
Nicorandil: D01810<JP> D01810<JP>
Pinacidil: D05482 D05482
Repaglinide: D00594<JP/US>
Tolazamide: D00379
Tolbutamide (DG00115): D00380 D06177
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    3767 (KCNJ11)
   04929 GnRH secretion
    3767 (KCNJ11)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    3767 (KCNJ11)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    3767 (KCNJ11)
Ion channels [BR:hsa04040]
 Voltage-gated cation channels
  Potassium channel, inwardly-rectifying (Kir)
   3767 (KCNJ11)
SSDB
Motif
Pfam: IRK_C IRK Ion_trans Ion_trans_2
Other DBs
NCBI-GeneID: 3767
NCBI-ProteinID: NP_000516
OMIM: 600937
HGNC: 6257
Ensembl: ENSG00000187486
UniProt: Q14654 B2RC52
Structure
LinkDB
Position
11:complement(17385248..17389346)
AA seq 390 aa
MLSRKGIIPEEYVLTRLAEDPAKPRYRARQRRARFVSKKGNCNVAHKNIREQGRFLQDVF
TTLVDLKWPHTLLIFTMSFLCSWLLFAMAWWLIAFAHGDLAPSEGTAEPCVTSIHSFSSA
FLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAET
LIFSKHAVIALRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPM
ENGVGGNSIFLVAPLIIYHVIDANSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQA
RTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTVKVPTPLCTARQLDEDHSLLEALT
LASARGPLRKRSVPMAKAKPKFSISPDSLS
NT seq 1173 nt   +upstreamnt  +downstreamnt
atgctgtcccgcaagggcatcatccccgaggaatacgtgctgacacgcctggcagaggac
cctgccaagcccaggtaccgtgcccgccagcggagggcccgctttgtgtccaagaaaggc
aactgcaacgtggcccacaagaacatccgggagcagggccgcttcctgcaggacgtgttc
accacgctggtggacctcaagtggccacacacattgctcatcttcaccatgtccttcctg
tgcagctggctgctcttcgccatggcctggtggctcatcgccttcgcccacggtgacctg
gcccccagcgagggcactgctgagccctgtgtcaccagcatccactccttctcgtctgcc
ttccttttctccattgaggtccaagtgactattggctttggggggcgcatggtgactgag
gagtgcccactggccatcctgatcctcatcgtgcagaacatcgtggggctcatgatcaac
gccatcatgcttggctgcatcttcatgaagactgcccaagcccaccgcagggctgagacc
ctcatcttcagcaagcatgcggtgatcgccctgcgccacggccgcctctgcttcatgcta
cgtgtgggtgacctccgcaagagcatgatcatcagcgccaccatccacatgcaggtggta
cgcaagaccaccagccccgagggcgaggtggtgcccctccaccaggtggacatccccatg
gagaacggcgtgggtggcaacagcatcttcctggtggccccgctgatcatctaccatgtc
attgatgccaacagcccactctacgacctggcacccagcgacctgcaccaccaccaggac
ctcgagatcatcgtcatcctggaaggcgtggtggaaaccacgggcatcaccacccaggcc
cgcacctcctacctggccgatgagatcctgtggggccagcgctttgtgcccattgtagct
gaggaggacggacgttactctgtggactactccaagtttggcaacaccgtcaaagtgccc
acaccactctgcacggcccgccagcttgatgaggaccacagcctactggaagctctgacc
ctcgcctcagcccgcgggcccctgcgcaagcgcagcgtgcccatggccaaggccaagccc
aagttcagcatctctccagattccctgtcctga

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