KEGG   PATHWAY: hyc00230
Entry
hyc00230                    Pathway                                
Name
Purine metabolism - Hydrogenophaga sp. PAMC20947
Class
Metabolism; Nucleotide metabolism
Pathway map
hyc00230  Purine metabolism
hyc00230

Module
hyc_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:hyc00230]
hyc_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:hyc00230]
hyc_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:hyc00230]
hyc_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:hyc00230]
hyc_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:hyc00230]
hyc_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:hyc00230]
hyc_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:hyc00230]
Other DBs
GO: 0006163 0042278
Organism
Hydrogenophaga sp. PAMC20947 [GN:hyc]
Gene
E5678_09270  NUDIX hydrolase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
E5678_04820  alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
E5678_06740  prs; ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
E5678_11265  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
E5678_10445  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
E5678_04420  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
E5678_21695  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
E5678_19770  purT; formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
E5678_05945  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
E5678_01240  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
E5678_19000  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
E5678_18995  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
E5678_18945  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
E5678_18065  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
E5678_20810  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
E5678_17630  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
E5678_12570  5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
E5678_07305  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
E5678_10475  pyrimidine/purine nucleoside phosphorylase [KO:K09913] [EC:2.4.2.1 2.4.2.2]
E5678_06730  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
E5678_05445  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
E5678_03940  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
E5678_11720  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
E5678_00435  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
E5678_00430  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
E5678_16715  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
E5678_05450  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
E5678_07830  GMP reductase [KO:K00364] [EC:1.7.1.7]
E5678_11135  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
E5678_11745  guanylate kinase [KO:K00942] [EC:2.7.4.8]
E5678_18565  adenosylcobalamin-dependent ribonucleoside-diphosphate reductase [KO:K00525] [EC:1.17.4.1]
E5678_20610  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
E5678_20605  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
E5678_12295  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
E5678_11185  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
E5678_06240  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
E5678_03640  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K00951] [EC:2.7.6.5]
E5678_18000  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
E5678_05575  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
E5678_06975  hypothetical protein [KO:K01768] [EC:4.6.1.1]
E5678_04015  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
E5678_20595  carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
E5678_19805  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
E5678_00470  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
E5678_04340  adenylate kinase [KO:K00939] [EC:2.7.4.3]
E5678_11100  symmetrical bis(5'-nucleosyl)-tetraphosphatase [KO:K01525] [EC:3.6.1.41]
E5678_05010  sulfate adenylyltransferase [KO:K00956] [EC:2.7.7.4]
E5678_05015  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
E5678_00050  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
E5678_00040  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
E5678_21825  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
E5678_21830  urease subunit beta [KO:K01429] [EC:3.5.1.5]
E5678_21835  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
E5678_05140  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
hyc00030  Pentose phosphate pathway
hyc00220  Arginine biosynthesis
hyc00250  Alanine, aspartate and glutamate metabolism
hyc00260  Glycine, serine and threonine metabolism
hyc00340  Histidine metabolism
hyc00630  Glyoxylate and dicarboxylate metabolism
hyc00730  Thiamine metabolism
hyc00740  Riboflavin metabolism
hyc00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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