KEGG   PATHWAY: koe00630
Entry
koe00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Klebsiella michiganensis E718
Class
Metabolism; Carbohydrate metabolism
Pathway map
koe00630  Glyoxylate and dicarboxylate metabolism
koe00630

Module
koe_M00012  Glyoxylate cycle [PATH:koe00630]
koe_M00621  Glycine cleavage system [PATH:koe00630]
Other DBs
GO: 0046487 0043648
Organism
Klebsiella michiganensis E718 [GN:koe]
Gene
A225_0273  Isocitrate lyase [KO:K01637] [EC:4.1.3.1]
A225_0358  Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
A225_0272  Malate synthase [KO:K01638] [EC:2.3.3.9]
A225_5255  Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
A225_1738  Citrate synthase (si) [KO:K01647] [EC:2.3.3.1]
A225_3906  Citrate synthase (si) [KO:K01647] [EC:2.3.3.1]
A225_0821  Putative enzyme [KO:K01681] [EC:4.2.1.3]
A225_2539  Aconitate hydratase [KO:K01681] [EC:4.2.1.3]
A225_0924  Aconitate hydratase 2 [KO:K01682] [EC:4.2.1.3 4.2.1.99]
A225_2167  Aconitate hydratase 2 [KO:K01682] [EC:4.2.1.3 4.2.1.99]
A225_4874  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
A225_4827  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
A225_4948  Methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
A225_1757  Methylaspartate mutase E subunit [KO:K19268] [EC:5.4.99.1]
A225_1759  Methylaspartate mutase S chain [KO:K01846] [EC:5.4.99.1]
A225_1756  Methylaspartate ammonia-lyase [KO:K04835] [EC:4.3.1.2]
A225_4143  Catalase [KO:K03781] [EC:1.11.1.6]
A225_2501  Catalase [KO:K03781] [EC:1.11.1.6]
A225_4496  D-3-phosphoglycerate dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
A225_2272  Putative 2-hydroxyacid dehydrogenase YcdW [KO:K12972] [EC:1.1.1.79 1.1.1.81]
A225_5582  2-ketogluconate 6-phosphate reductase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
A225_5378  Phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
A225_0007  Glutamine synthetase type I [KO:K01915] [EC:6.3.1.2]
A225_4400  Serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
A225_4934  Glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
A225_4936  Aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
A225_0920  Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex [KO:K00382] [EC:1.8.1.4]
A225_2957  Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex [KO:K00382] [EC:1.8.1.4]
A225_4935  Glycine cleavage system H protein [KO:K02437]
A225_5142  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
A225_4878  Glycerate kinase [KO:K00865] [EC:2.7.1.165]
A225_5141  Glycerate kinase [KO:K00865] [EC:2.7.1.165]
A225_4696  Glycerate kinase [KO:K00865] [EC:2.7.1.165]
A225_2777  Aldehyde dehydrogenase A [KO:K07248] [EC:1.2.1.22 1.2.1.21]
A225_4622  Lactaldehyde reductase [KO:K00048] [EC:1.1.1.77]
A225_5251  L(+)-tartrate dehydratase alpha subunit [KO:K03779] [EC:4.2.1.32]
A225_5250  L(+)-tartrate dehydratase beta subunit [KO:K03780] [EC:4.2.1.32]
A225_2229  Tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
A225_3662  4-Hydroxy-2-oxoglutarate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
A225_0017  Formate dehydrogenase O alpha subunit [KO:K00123] [EC:1.17.1.9]
A225_0016  Formate dehydrogenase O beta subunit [KO:K00124]
A225_0015  Formate dehydrogenase O gamma subunit [KO:K00127]
A225_3499  Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
A225_1118  N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
koe00010  Glycolysis / Gluconeogenesis
koe00020  Citrate cycle (TCA cycle)
koe00030  Pentose phosphate pathway
koe00053  Ascorbate and aldarate metabolism
koe00071  Fatty acid degradation
koe00230  Purine metabolism
koe00250  Alanine, aspartate and glutamate metabolism
koe00260  Glycine, serine and threonine metabolism
koe00620  Pyruvate metabolism
koe00710  Carbon fixation by Calvin cycle
koe00750  Vitamin B6 metabolism
koe00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

DBGET integrated database retrieval system