KEGG   PATHWAY: koy00230
Entry
koy00230                    Pathway                                
Name
Purine metabolism - Klebsiella michiganensis HKOPL1
Class
Metabolism; Nucleotide metabolism
Pathway map
koy00230  Purine metabolism
koy00230

Module
koy_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:koy00230]
koy_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:koy00230]
koy_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:koy00230]
koy_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:koy00230]
koy_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:koy00230]
Other DBs
GO: 0006163 0042278
Organism
Klebsiella michiganensis HKOPL1 [GN:koy]
Gene
J415_06790  nudF; ADP-ribose pyrophosphatase NudF [KO:K01515] [EC:3.6.1.13 3.6.1.-]
J415_05115  nudE; adenosine nucleotide hydrolase NudE [KO:K08312] [EC:3.6.1.-]
J415_27420  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
J415_23105  phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
J415_05275  hypothetical protein [KO:K00948] [EC:2.7.6.1]
J415_14440  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
J415_11075  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
J415_01725  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
J415_10470  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
J415_13780  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
J415_09965  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
J415_10475  phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
J415_24360  phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
J415_24355  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
J415_10540  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
J415_20005  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
J415_01720  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
J415_24565  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
J415_24480  ushA; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor [KO:K11751] [EC:3.1.3.5 3.6.1.45]
J415_08660  surE; 5'(3')-nucleotidase/polyphosphatase [KO:K03787] [EC:3.1.3.5 3.1.3.6]
J415_00010  acid phosphatase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
J415_23190  UMP phosphatase [KO:K02566] [EC:3.1.3.5]
J415_05105  GMP/IMP nucleotidase [KO:K20881] [EC:3.1.3.-]
J415_24530  inosine/guanosine kinase [KO:K00892] [EC:2.7.1.73]
J415_10830  purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
J415_27415  deoD; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
J415_25180  hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
J415_09805  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
J415_14985  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
J415_26570  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
J415_10410  inosine 5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
J415_10185  ndk; multifunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase [KO:K00940] [EC:2.7.4.6]
J415_27370  inosine/xanthosine triphosphatase [KO:K01529] [EC:3.6.1.73]
J415_07050  dITP/XTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
J415_25955  xanthine-guanine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
J415_17310  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
J415_10415  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
J415_10750  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
J415_26720  guanosine 5'-monophosphate oxidoreductase [KO:K00364] [EC:1.7.1.7]
J415_03760  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
J415_09270  ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
J415_11505  ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
J415_11500  nrdB; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
J415_09265  nrdF; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
J415_00515  anaerobic ribonucleoside triphosphate reductase [KO:K21636] [EC:1.1.98.6]
J415_26305  dgt; deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
J415_00160  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
J415_11215  5'-nucleotidase [KO:K08722] [EC:3.1.3.89]
J415_03750  bifunctional (p)ppGpp synthetase II/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
J415_10440  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
J415_02215  guanosine pentaphosphate phosphohydrolase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
J415_08540  relA; (p)ppGpp synthetase I/GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
J415_02120  cyaA; adenylate cyclase [KO:K05851] [EC:4.6.1.1]
J415_00880  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
J415_15640  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
J415_13315  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
J415_08475  decarboxylase [KO:K06966] [EC:3.2.2.10 3.2.2.-]
J415_12045  adenine deaminase [KO:K01486] [EC:3.5.4.2]
J415_00720  cpdB; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
J415_24540  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
J415_08545  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
J415_00330  3',5'-cyclic-nucleotide phosphodiesterase [KO:K03651] [EC:3.1.4.53]
J415_06800  cyclic 3',5'-adenosine monophosphate phosphodiesterase [KO:K03651] [EC:3.1.4.53]
J415_27035  apaH; diadenosine tetraphosphatase [KO:K01525] [EC:3.6.1.41]
J415_08630  adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
J415_08625  cysN; sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
J415_08620  sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
J415_20795  hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
J415_14290  hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
J415_20800  2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) decarboxylase [KO:K16840] [EC:4.1.1.97]
J415_20770  hydantoin racemase [KO:K16841] [EC:5.1.99.3]
J415_20765  polysaccharide deacetylase [KO:K16842] [EC:3.5.2.5]
J415_20705  allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
J415_06670  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
J415_06675  ureB; urease subunit beta [KO:K01429] [EC:3.5.1.5]
J415_06680  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
J415_20755  amidase [KO:K22601] [EC:2.1.3.5]
J415_20745  gamma-glutamyltransferase [KO:K22602] [EC:3.5.1.126]
J415_14370  amino acid kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
koy00030  Pentose phosphate pathway
koy00220  Arginine biosynthesis
koy00250  Alanine, aspartate and glutamate metabolism
koy00260  Glycine, serine and threonine metabolism
koy00340  Histidine metabolism
koy00630  Glyoxylate and dicarboxylate metabolism
koy00730  Thiamine metabolism
koy00740  Riboflavin metabolism
koy00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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