KEGG   PATHWAY: kpb00330
Entry
kpb00330                    Pathway                                
Name
Arginine and proline metabolism - Klebsiella pneumoniae blaNDM-1
Class
Metabolism; Amino acid metabolism
Pathway map
kpb00330  Arginine and proline metabolism
kpb00330

Module
kpb_M00015  Proline biosynthesis, glutamate => proline [PATH:kpb00330]
kpb_M00133  Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:kpb00330]
kpb_M00136  GABA biosynthesis, prokaryotes, putrescine => GABA [PATH:kpb00330]
kpb_M00879  Arginine succinyltransferase pathway, arginine => glutamate [PATH:kpb00330]
kpb_M00970  Proline degradation, proline => glutamate [PATH:kpb00330]
Other DBs
GO: 0006525 0006560
Organism
Klebsiella pneumoniae blaNDM-1 [GN:kpb]
Gene
FH42_06310  creatinine amidohydrolase [KO:K01470] [EC:3.5.2.10]
FH42_24195  cytosine deaminase [KO:K01485] [EC:3.5.4.1 3.5.4.21]
FH42_15085  cytosine deaminase [KO:K01485] [EC:3.5.4.1 3.5.4.21]
FH42_06300  hypothetical protein [KO:K01485] [EC:3.5.4.1 3.5.4.21]
FH42_12850  arginine decarboxylase [KO:K01585] [EC:4.1.1.19]
FH42_12845  agmatinase [KO:K01480] [EC:3.5.3.11]
FH42_12970  ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
FH42_21455  spermidine synthase [KO:K00797] [EC:2.5.1.16]
FH42_21450  S-adenosylmethionine decarboxylase [KO:K01611] [EC:4.1.1.50]
FH42_13790  putrescine--2-oxoglutarate aminotransferase [KO:K09251] [EC:2.6.1.82]
FH42_05710  gamma-aminobutyraldehyde dehydrogenase [KO:K00137] [EC:1.2.1.19]
FH42_03825  spermidine acetyltransferase [KO:K00657] [EC:2.3.1.57]
FH42_10870  agmatinase [KO:K12255] [EC:3.5.3.7]
FH42_01975  arginine succinyltransferase [KO:K00673] [EC:2.3.1.109]
FH42_03370  arginine N-succinyltransferase [KO:K00673] [EC:2.3.1.109]
FH42_01985  succinylarginine dihydrolase [KO:K01484] [EC:3.5.3.23]
FH42_03380  N-succinylarginine dihydrolase [KO:K01484] [EC:3.5.3.23]
FH42_01970  acetylornithine aminotransferase [KO:K00840] [EC:2.6.1.81]
FH42_03365  argD; acetylornithine aminotransferase [KO:K00840] [EC:2.6.1.81]
FH42_01980  astD; succinylglutamate-semialdehyde dehydrogenase [KO:K06447] [EC:1.2.1.71]
FH42_03375  astD; succinylglutamate-semialdehyde dehydrogenase [KO:K06447] [EC:1.2.1.71]
FH42_01990  succinylglutamate desuccinylase [KO:K05526] [EC:3.5.1.96]
FH42_03385  succinylglutamate desuccinylase [KO:K05526] [EC:3.5.1.96]
FH42_00960  gamma-glutamylputrescine synthetase [KO:K09470] [EC:6.3.1.11]
FH42_23650  FAD-dependent oxidoreductase [KO:K09471] [EC:1.4.3.-]
FH42_00940  gamma-glutamylputrescine oxidoreductase [KO:K09471] [EC:1.4.3.-]
FH42_00945  aldehyde dehydrogenase [KO:K09472] [EC:1.2.1.99]
FH42_00955  gamma-glutamyl-gamma-aminobutyrate hydrolase [KO:K09473] [EC:3.5.1.94]
FH42_22565  pyrroline-5-carboxylate reductase [KO:K00286] [EC:1.5.1.2]
FH42_01060  putA; transcriptional regulator [KO:K13821] [EC:1.5.5.2 1.2.1.88]
FH42_22305  gamma-glutamyl kinase [KO:K00931] [EC:2.7.2.11]
FH42_22300  gamma-glutamyl phosphate reductase [KO:K00147] [EC:1.2.1.41]
FH42_00675  aromatic amino acid aminotransferase [KO:K00813] [EC:2.6.1.1]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
kpb00020  Citrate cycle (TCA cycle)
kpb00220  Arginine biosynthesis
kpb00250  Alanine, aspartate and glutamate metabolism
kpb00260  Glycine, serine and threonine metabolism
kpb00270  Cysteine and methionine metabolism
kpb00310  Lysine degradation
kpb00410  beta-Alanine metabolism
kpb00470  D-Amino acid metabolism
kpb00480  Glutathione metabolism
kpb00630  Glyoxylate and dicarboxylate metabolism
kpb00650  Butanoate metabolism
kpb00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   
LinkDB

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