KEGG   PATHWAY: kpt00230
Entry
kpt00230                    Pathway                                
Name
Purine metabolism - Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1
Class
Metabolism; Nucleotide metabolism
Pathway map
kpt00230  Purine metabolism
kpt00230

Module
kpt_M00005  PRPP biosynthesis, ribose-5P => PRPP [PATH:kpt00230]
kpt_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:kpt00230]
kpt_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:kpt00230]
kpt_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:kpt00230]
kpt_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:kpt00230]
Other DBs
GO: 0006163 0042278
Organism
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1 [GN:kpt]
Gene
VK055_0084  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
VK055_0212  prsA; ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
VK055_0346  [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
VK055_0434  [KO:K03787] [EC:3.1.3.5 3.1.3.6]
VK055_0519  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
VK055_0675  [KO:K01951] [EC:6.3.5.2]
VK055_0697  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
VK055_0700  [KO:K16841] [EC:5.1.99.3]
VK055_0702  [KO:K16842] [EC:3.5.2.5]
VK055_0707  [KO:K01951] [EC:6.3.5.2]
VK055_0719  [KO:K22601] [EC:2.1.3.5]
VK055_0721  [KO:K22602] [EC:3.5.1.126]
VK055_0727  pucG; purine catabolism protein pucG [KO:K00839] [EC:2.6.1.112]
VK055_0728  [KO:K02083] [EC:3.5.3.9]
VK055_0821  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
VK055_0822  [KO:K16840] [EC:4.1.1.97]
VK055_0825  [KO:K16839] [EC:1.14.13.113]
VK055_1323  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
VK055_1820  pgm; phosphoglucomutase, alpha-D-glucose phosphate-specific [KO:K01835] [EC:5.4.2.2]
VK055_1835  [KO:K02566] [EC:3.1.3.5]
VK055_2060  uraH2; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
VK055_2069  purE; purE [KO:K01588] [EC:5.4.99.18]
VK055_2070  purK; phosphoribosylaminoimidazole carboxylase, ATPasesubunit [KO:K01589] [EC:6.3.4.18]
VK055_2087  [KO:K11751] [EC:3.1.3.5 3.6.1.45]
VK055_2091  [KO:K00892] [EC:2.7.1.73]
VK055_2093  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
VK055_2098  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
VK055_2221  [KO:K09913] [EC:2.4.2.1 2.4.2.2]
VK055_2316  gpt; gpt [KO:K00769] [EC:2.4.2.22]
VK055_2390  dgt; dgt [KO:K01129] [EC:3.1.5.1]
VK055_2435  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
VK055_2464  guaC; guanosine monophosphate reductase [KO:K00364] [EC:1.7.1.7]
VK055_2528  apaH; diadenosine tetraphosphatase [KO:K01525] [EC:3.6.1.41]
VK055_2583  yjjX; ITPase/XTPase [KO:K01529]
VK055_2591  deoD; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
VK055_2592  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
VK055_2772  [KO:K03651] [EC:3.1.4.53]
VK055_2818  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
VK055_2857  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
VK055_2887  purA; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
VK055_3086  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
VK055_3088  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
VK055_3170  [KO:K05851] [EC:4.6.1.1]
VK055_3195  [KO:K01524] [EC:3.6.1.11 3.6.1.40]
VK055_3438  [KO:K01515] [EC:3.6.1.13 3.6.1.-]
VK055_3470  spoT; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
VK055_3472  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
VK055_3701  [KO:K20881] [EC:3.1.3.-]
VK055_3703  [KO:K08312] [EC:3.6.1.-]
VK055_4003  ureC; urease, alpha subunit [KO:K01428] [EC:3.5.1.5]
VK055_4004  ureB; urease subunit beta [KO:K01429] [EC:3.5.1.5]
VK055_4005  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
VK055_4026  nudF; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
VK055_4028  [KO:K03651] [EC:3.1.4.53]
VK055_4090  rdgB; non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
VK055_4194  ureC2; urease, alpha subunit [KO:K01428] [EC:3.5.1.5]
VK055_4195  ureB2; urease subunit beta [KO:K01429] [EC:3.5.1.5]
VK055_4376  ygdH; putative oxidoreductase [KO:K06966] [EC:3.2.2.10 3.2.2.-]
VK055_4388  [KO:K00951] [EC:2.7.6.5]
VK055_4389  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
VK055_4402  cysD; cysD [KO:K00957] [EC:2.7.7.4]
VK055_4403  cysN; cysN [KO:K00956] [EC:2.7.7.4]
VK055_4404  cysC; adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
VK055_4410  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
VK055_4510  nrdF2; ribonucleoside-diphosphate reductase subunit beta nrdF2 [KO:K00526] [EC:1.17.4.1]
VK055_4511  [KO:K00525] [EC:1.17.4.1]
VK055_4584  [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
VK055_4619  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
VK055_4652  ndk; ndk [KO:K00940] [EC:2.7.4.6]
VK055_4665  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
VK055_4666  guaA; guaA GMP synthetase [KO:K01951] [EC:6.3.5.2]
VK055_4683  ppx; ppx [KO:K01524] [EC:3.6.1.11 3.6.1.40]
VK055_4685  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
VK055_4686  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
VK055_4701  purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
VK055_4780  [KO:K01487] [EC:3.5.4.3]
VK055_4811  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
VK055_4833  yfbR; deoxyribonucleoside 5'-monophosphate phosphatase [KO:K08722] [EC:3.1.3.89]
VK055_4872  nrdB; nrdB [KO:K00526] [EC:1.17.4.1]
VK055_4873  [KO:K00525] [EC:1.17.4.1]
VK055_4969  ade2; adenine deaminase 2 [KO:K01486] [EC:3.5.4.2]
VK055_5132  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
kpt00030  Pentose phosphate pathway
kpt00220  Arginine biosynthesis
kpt00250  Alanine, aspartate and glutamate metabolism
kpt00260  Glycine, serine and threonine metabolism
kpt00340  Histidine metabolism
kpt00630  Glyoxylate and dicarboxylate metabolism
kpt00730  Thiamine metabolism
kpt00740  Riboflavin metabolism
kpt00790  Folate biosynthesis
KO pathway
ko00230   

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