KEGG   PATHWAY: mgro00230
Entry
mgro00230                   Pathway                                
Name
Purine metabolism - Mycolicibacterium grossiae
Class
Metabolism; Nucleotide metabolism
Pathway map
mgro00230  Purine metabolism
mgro00230

Module
mgro_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:mgro00230]
mgro_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:mgro00230]
mgro_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:mgro00230]
mgro_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:mgro00230]
mgro_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:mgro00230]
mgro_M00546  Purine degradation, xanthine => urea [PATH:mgro00230]
mgro_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:mgro00230]
mgro_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:mgro00230]
Other DBs
GO: 0006163 0042278
Organism
Mycolicibacterium grossiae [GN:mgro]
Gene
FZ046_00030  [KO:K01524] [EC:3.6.1.11 3.6.1.40]
FZ046_00070  [KO:K04765] [EC:3.6.1.9]
FZ046_00100  [KO:K00948] [EC:2.7.6.1]
FZ046_00355  [KO:K13483]
FZ046_00360  [KO:K11178] [EC:1.17.1.4]
FZ046_00365  [KO:K11177] [EC:1.17.1.4]
FZ046_00525  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
FZ046_00530  [KO:K11175] [EC:2.1.2.2]
FZ046_01200  [KO:K01129] [EC:3.1.5.1]
FZ046_02035  [KO:K01933] [EC:6.3.3.1]
FZ046_02050  [KO:K00764] [EC:2.4.2.14]
FZ046_02070  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269]
FZ046_02110  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265]
FZ046_02115  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264]
FZ046_02150  [KO:K01923] [EC:6.3.2.6]
FZ046_02170  [KO:K01756] [EC:4.3.2.2]
FZ046_02190  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
FZ046_03215  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
FZ046_03240  [KO:K16840] [EC:4.1.1.97]
FZ046_03390  [KO:K01768] [EC:4.6.1.1]
FZ046_07190  [KO:K00526] [EC:1.17.4.1]
FZ046_08520  cysC; adenylyl-sulfate kinase [KO:K00955] [EC:2.7.7.4 2.7.1.25]
FZ046_08525  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
FZ046_08880  [KO:K01487] [EC:3.5.4.3]
FZ046_08995  [KO:K01939] [EC:6.3.4.4]
FZ046_09050  [KO:K08289] [EC:6.3.1.21]
FZ046_09650  [KO:K01524] [EC:3.6.1.11 3.6.1.40]
FZ046_10425  [KO:K11177] [EC:1.17.1.4]
FZ046_10430  [KO:K11178] [EC:1.17.1.4]
FZ046_10435  [KO:K13483]
FZ046_11570  [KO:K00939] [EC:2.7.4.3]
FZ046_11945  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
FZ046_11950  [KO:K00088] [EC:1.1.1.205]
FZ046_11960  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
FZ046_12020  [KO:K01239] [EC:3.2.2.1]
FZ046_12285  [KO:K01488] [EC:3.5.4.4]
FZ046_12365  [KO:K03783] [EC:2.4.2.1]
FZ046_12525  [KO:K13483]
FZ046_12530  [KO:K11178] [EC:1.17.1.4]
FZ046_12535  [KO:K11177] [EC:1.17.1.4]
FZ046_12950  pucL; urate oxidase [KO:K00365] [EC:1.7.3.3]
FZ046_12955  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
FZ046_12960  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
FZ046_13135  [KO:K01589] [EC:6.3.4.18]
FZ046_13140  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
FZ046_14805  [KO:K01835] [EC:5.4.2.2]
FZ046_14935  [KO:K01768] [EC:4.6.1.1]
FZ046_15345  nrdE; class 1b ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
FZ046_15390  nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
FZ046_15460  allB; allantoinase AllB [KO:K01466] [EC:3.5.2.5]
FZ046_15465  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
FZ046_16070  [KO:K02566] [EC:3.1.3.5]
FZ046_16385  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
FZ046_17660  [KO:K19710] [EC:2.7.7.53]
FZ046_17795  [KO:K00759] [EC:2.4.2.7]
FZ046_18135  [KO:K00942] [EC:2.7.4.8]
FZ046_19005  [KO:K01768] [EC:4.6.1.1]
FZ046_19895  [KO:K26110]
FZ046_19925  [KO:K01430] [EC:3.5.1.5]
FZ046_19930  [KO:K01429] [EC:3.5.1.5]
FZ046_19935  [KO:K01428] [EC:3.5.1.5]
FZ046_20480  [KO:K11178] [EC:1.17.1.4]
FZ046_20485  [KO:K13483]
FZ046_20490  [KO:K11177] [EC:1.17.1.4]
FZ046_21250  [KO:K14977] [EC:3.5.3.26]
FZ046_21255  [KO:K16841] [EC:5.1.99.3]
FZ046_21265  allB; allantoinase AllB [KO:K01466] [EC:3.5.2.5]
FZ046_22060  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
FZ046_22285  [KO:K00856] [EC:2.7.1.20]
FZ046_22985  [KO:K01129] [EC:3.1.5.1]
FZ046_23450  [KO:K00940] [EC:2.7.4.6]
FZ046_24885  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
FZ046_25375  cysN; sulfate adenylyltransferase subunit CysN [KO:K00955] [EC:2.7.7.4 2.7.1.25]
FZ046_25380  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
FZ046_25545  [KO:K01768] [EC:4.6.1.1]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
mgro00030  Pentose phosphate pathway
mgro00220  Arginine biosynthesis
mgro00250  Alanine, aspartate and glutamate metabolism
mgro00260  Glycine, serine and threonine metabolism
mgro00340  Histidine metabolism
mgro00630  Glyoxylate and dicarboxylate metabolism
mgro00730  Thiamine metabolism
mgro00740  Riboflavin metabolism
mgro00790  Folate biosynthesis
KO pathway
ko00230   

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