KEGG   PATHWAY: mmes00230
Entry
mmes00230                   Pathway                                
Name
Purine metabolism - Methylobacterium mesophilicum
Class
Metabolism; Nucleotide metabolism
Pathway map
mmes00230  Purine metabolism
mmes00230

Module
mmes_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:mmes00230]
mmes_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:mmes00230]
mmes_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:mmes00230]
mmes_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:mmes00230]
mmes_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:mmes00230]
mmes_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:mmes00230]
Other DBs
GO: 0006163 0042278
Organism
Methylobacterium mesophilicum [GN:mmes]
Gene
MMSR116_00315  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
MMSR116_01100  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
MMSR116_01475  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
MMSR116_01840  [KO:K13483]
MMSR116_01845  [KO:K11178] [EC:1.17.1.4]
MMSR116_01850  [KO:K11177] [EC:1.17.1.4]
MMSR116_01895  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
MMSR116_02130  [KO:K01768] [EC:4.6.1.1]
MMSR116_02345  [KO:K01768] [EC:4.6.1.1]
MMSR116_02835  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
MMSR116_03630  [KO:K01951] [EC:6.3.5.2]
MMSR116_04125  [KO:K00948] [EC:2.7.6.1]
MMSR116_04175  [KO:K14977] [EC:3.5.3.26]
MMSR116_04900  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264]
MMSR116_04905  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265]
MMSR116_06230  [KO:K01768] [EC:4.6.1.1]
MMSR116_06270  [KO:K16841] [EC:5.1.99.3]
MMSR116_06885  [KO:K00525] [EC:1.17.4.1]
MMSR116_06935  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K13485] [EC:4.1.1.97]
MMSR116_06940  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
MMSR116_06945  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
MMSR116_06965  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
MMSR116_06975  [KO:K14977] [EC:3.5.3.26]
MMSR116_06980  [KO:K01483] [EC:4.3.2.3]
MMSR116_07040  pucL; urate oxidase [KO:K00365] [EC:1.7.3.3]
MMSR116_07230  [KO:K01524] [EC:3.6.1.11 3.6.1.40]
MMSR116_07510  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
MMSR116_08675  paoA; aldehyde dehydrogenase iron-sulfur subunit [KO:K13483]
MMSR116_08680  [KO:K11178] [EC:1.17.1.4]
MMSR116_08685  [KO:K11177] [EC:1.17.1.4]
MMSR116_09450  [KO:K13483]
MMSR116_09455  [KO:K11178] [EC:1.17.1.4]
MMSR116_09460  [KO:K11177] [EC:1.17.1.4]
MMSR116_10075  [KO:K03783] [EC:2.4.2.1]
MMSR116_10235  [KO:K00764] [EC:2.4.2.14]
MMSR116_10510  [KO:K01923] [EC:6.3.2.6]
MMSR116_11225  [KO:K01768] [EC:4.6.1.1]
MMSR116_11330  [KO:K01939] [EC:6.3.4.4]
MMSR116_11345  [KO:K01756] [EC:4.3.2.2]
MMSR116_11895  [KO:K01768] [EC:4.6.1.1]
MMSR116_12625  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
MMSR116_12850  [KO:K09769] [EC:3.1.4.16]
MMSR116_13175  paoA; aldehyde dehydrogenase iron-sulfur subunit [KO:K13483]
MMSR116_13180  [KO:K11178] [EC:1.17.1.4]
MMSR116_13185  [KO:K11177] [EC:1.17.1.4]
MMSR116_13290  [KO:K01487] [EC:3.5.4.3]
MMSR116_13395  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
MMSR116_13400  [KO:K14048] [EC:3.5.1.5]
MMSR116_13475  ade; adenine deaminase [KO:K01486] [EC:3.5.4.2]
MMSR116_13840  [KO:K01129] [EC:3.1.5.1]
MMSR116_14315  [KO:K01768] [EC:4.6.1.1]
MMSR116_15010  [KO:K01768] [EC:4.6.1.1]
MMSR116_16280  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
MMSR116_16295  [KO:K01241] [EC:3.2.2.4]
MMSR116_16485  [KO:K00940] [EC:2.7.4.6]
MMSR116_16495  [KO:K11175] [EC:2.1.2.2]
MMSR116_16500  [KO:K01933] [EC:6.3.3.1]
MMSR116_16900  [KO:K01768] [EC:4.6.1.1]
MMSR116_17080  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
MMSR116_17090  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K13485] [EC:4.1.1.97]
MMSR116_17190  [KO:K01768] [EC:4.6.1.1]
MMSR116_17360  [KO:K11177] [EC:1.17.1.4]
MMSR116_18685  [KO:K03651] [EC:3.1.4.53]
MMSR116_18705  [KO:K01768] [EC:4.6.1.1]
MMSR116_18905  [KO:K01768] [EC:4.6.1.1]
MMSR116_19195  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
MMSR116_19860  [KO:K01768] [EC:4.6.1.1]
MMSR116_20305  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
MMSR116_21035  [KO:K00942] [EC:2.7.4.8]
MMSR116_21660  [KO:K01768] [EC:4.6.1.1]
MMSR116_21880  [KO:K01839] [EC:5.4.2.7]
MMSR116_22535  [KO:K01589] [EC:6.3.4.18]
MMSR116_22540  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
MMSR116_22920  cysN; sulfate adenylyltransferase subunit CysN [KO:K00956] [EC:2.7.7.4]
MMSR116_22925  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
MMSR116_23125  [KO:K01835] [EC:5.4.2.2]
MMSR116_23195  [KO:K00939] [EC:2.7.4.3]
MMSR116_24465  [KO:K06952] [EC:3.1.3.89]
MMSR116_25260  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269]
MMSR116_26160  [KO:K01768] [EC:4.6.1.1]
MMSR116_26520  [KO:K01139] [EC:2.7.6.5 3.1.7.2]
MMSR116_26575  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
MMSR116_26640  [KO:K22602] [EC:3.5.1.126]
MMSR116_26675  [KO:K01768] [EC:4.6.1.1]
MMSR116_28515  [KO:K01487] [EC:3.5.4.3]
MMSR116_30750  [KO:K00759] [EC:2.4.2.7]
MMSR116_30835  [KO:K01923] [EC:6.3.2.6]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
mmes00030  Pentose phosphate pathway
mmes00220  Arginine biosynthesis
mmes00250  Alanine, aspartate and glutamate metabolism
mmes00260  Glycine, serine and threonine metabolism
mmes00340  Histidine metabolism
mmes00630  Glyoxylate and dicarboxylate metabolism
mmes00730  Thiamine metabolism
mmes00740  Riboflavin metabolism
mmes00790  Folate biosynthesis
KO pathway
ko00230   

DBGET integrated database retrieval system