KEGG   PATHWAY: mno00230
Entry
mno00230                    Pathway                                
Name
Purine metabolism - Methylobacterium nodulans
Class
Metabolism; Nucleotide metabolism
Pathway map
mno00230  Purine metabolism
mno00230

Module
mno_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:mno00230]
mno_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:mno00230]
mno_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:mno00230]
mno_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:mno00230]
mno_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:mno00230]
mno_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:mno00230]
Other DBs
GO: 0006163 0042278
Organism
Methylobacterium nodulans [GN:mno]
Gene
Mnod_5000  NUDIX hydrolase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
Mnod_5134  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
Mnod_2089  phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I [KO:K01835] [EC:5.4.2.2]
Mnod_1184  phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I [KO:K15778] [EC:5.4.2.8 5.4.2.2]
Mnod_6610  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
Mnod_4629  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
Mnod_6598  phosphoribosylamine/glycine ligase [KO:K01945] [EC:6.3.4.13]
Mnod_5548  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
Mnod_0008  phosphoribosylformylglycinamidine synthase II [KO:K23269] [EC:6.3.5.3]
Mnod_1673  phosphoribosylformylglycinamidine synthase, purS [KO:K23264] [EC:6.3.5.3]
Mnod_1674  phosphoribosylformylglycinamidine synthase I [KO:K23265] [EC:6.3.5.3 3.5.1.2]
Mnod_5547  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
Mnod_2076  phosphoribosylaminoimidazole carboxylase, ATPase subunit [KO:K01589] [EC:6.3.4.18]
Mnod_2077  phosphoribosylaminoimidazole carboxylase, catalytic subunit [KO:K01588] [EC:5.4.99.18]
Mnod_1843  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
Mnod_3701  SAICAR synthetase [KO:K01923] [EC:6.3.2.6]
Mnod_7577  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
Mnod_5222  phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
Mnod_7279  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
Mnod_4645  5'-Nucleotidase domain protein [KO:K11751] [EC:3.1.3.5 3.6.1.45]
Mnod_7398  stationary-phase survival protein SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
Mnod_0509  purine nucleotide phosphorylase [KO:K03783] [EC:2.4.2.1]
Mnod_5255  protein of unknown function DUF152 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
Mnod_1156  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
Mnod_1289  inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
Mnod_4923  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
Mnod_4764  non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
Mnod_7666  phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
Mnod_8337  aldehyde oxidase and xanthine dehydrogenase molybdopterin binding [KO:K11177] [EC:1.17.1.4]
Mnod_2924  aldehyde oxidase and xanthine dehydrogenase molybdopterin binding [KO:K11177] [EC:1.17.1.4]
Mnod_8336  molybdopterin dehydrogenase FAD-binding [KO:K11178] [EC:1.17.1.4]
Mnod_2923  molybdopterin dehydrogenase FAD-binding [KO:K11178] [EC:1.17.1.4]
Mnod_2922  (2Fe-2S)-binding domain protein [KO:K13483]
Mnod_8335  (2Fe-2S)-binding domain protein [KO:K13483]
Mnod_0664  glutamine amidotransferase class-I [KO:K01951] [EC:6.3.5.2]
Mnod_1294  GMP synthase, large subunit [KO:K01951] [EC:6.3.5.2]
Mnod_4655  guanine deaminase [KO:K01487] [EC:3.5.4.3]
Mnod_8645  CMP/dCMP deaminase zinc-binding [KO:K01487] [EC:3.5.4.3]
Mnod_2781  guanylate kinase [KO:K00942] [EC:2.7.4.8]
Mnod_6038  ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent [KO:K00525] [EC:1.17.4.1]
Mnod_2170  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
Mnod_6705  metal-dependent phosphohydrolase [KO:K06952] [EC:3.1.3.89]
Mnod_0033  (p)ppGpp synthetase I, SpoT/RelA [KO:K01139] [EC:2.7.6.5 3.1.7.2]
Mnod_5542  Ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Mnod_1516  Ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Mnod_3461  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Mnod_4597  adenylate/guanylate cyclase with Chase sensor [KO:K01768] [EC:4.6.1.1]
Mnod_0315  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Mnod_7519  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Mnod_0163  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Mnod_4159  putative adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Mnod_3196  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Mnod_4495  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Mnod_0089  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Mnod_0096  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Mnod_0812  putative adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Mnod_1307  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Mnod_2387  adenylate/guanylate cyclase with integral membrane sensor [KO:K01768] [EC:4.6.1.1]
Mnod_5726  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
Mnod_6613  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
Mnod_5259  putative adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Mnod_7722  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
Mnod_7581  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
Mnod_4743  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
Mnod_0385  adenine deaminase [KO:K01486] [EC:3.5.4.2]
Mnod_4543  metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
Mnod_1929  adenylate kinase [KO:K00939] [EC:2.7.4.3]
Mnod_6550  MazG family protein [KO:K04765] [EC:3.6.1.9]
Mnod_6750  metallophosphoesterase [KO:K03651] [EC:3.1.4.53]
Mnod_4837  adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
Mnod_4032  adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
Mnod_1799  sulfate adenylyltransferase, large subunit [KO:K00956] [EC:2.7.7.4]
Mnod_1800  sulfate adenylyltransferase, small subunit [KO:K00957] [EC:2.7.7.4]
Mnod_5813  urate oxidase [KO:K00365] [EC:1.7.3.3]
Mnod_6858  FAD-dependent pyridine nucleotide-disulphide oxidoreductase
Mnod_6873  FAD-dependent pyridine nucleotide-disulphide oxidoreductase
Mnod_5814  hydroxyisourate hydrolase [KO:K13485] [EC:4.1.1.97]
Mnod_5914  Asp/Glu/hydantoin racemase [KO:K16841] [EC:5.1.99.3]
Mnod_7936  Asp/Glu/hydantoin racemase [KO:K16841] [EC:5.1.99.3]
Mnod_5365  urate catabolism protein [KO:K16842] [EC:3.5.2.5]
Mnod_7819  allantoin catabolism protein [KO:K14977] [EC:3.5.3.26]
Mnod_7820  Ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
Mnod_0399  urease, alpha subunit [KO:K01428] [EC:3.5.1.5]
Mnod_0398  urease, gamma subunit [KO:K14048] [EC:3.5.1.5]
Mnod_1832  gamma-glutamyltranspeptidase [KO:K22602] [EC:3.5.1.126]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
mno00030  Pentose phosphate pathway
mno00220  Arginine biosynthesis
mno00250  Alanine, aspartate and glutamate metabolism
mno00260  Glycine, serine and threonine metabolism
mno00340  Histidine metabolism
mno00630  Glyoxylate and dicarboxylate metabolism
mno00730  Thiamine metabolism
mno00740  Riboflavin metabolism
mno00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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