KEGG   PATHWAY: mrf00630
Entry
mrf00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycolicibacterium rufum
Class
Metabolism; Carbohydrate metabolism
Pathway map
mrf00630  Glyoxylate and dicarboxylate metabolism
mrf00630

Module
mrf_M00012  Glyoxylate cycle [PATH:mrf00630]
mrf_M00621  Glycine cleavage system [PATH:mrf00630]
mrf_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mrf00630]
Other DBs
GO: 0046487 0043648
Organism
Mycolicibacterium rufum [GN:mrf]
Gene
MJO55_03190  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
MJO55_14675  aceA; isocitrate lyase ICL2 [KO:K01637] [EC:4.1.3.1 4.1.3.30]
MJO55_22760  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
MJO55_24750  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
MJO55_05680  acsA; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
MJO55_14100  malate synthase G [KO:K01638] [EC:2.3.3.9]
MJO55_14250  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
MJO55_22825  citrate synthase [KO:K01647] [EC:2.3.3.1]
MJO55_22845  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
MJO55_12440  aconitate hydratase [KO:K27802] [EC:4.2.1.3 4.2.1.99]
MJO55_22455  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MJO55_23025  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
MJO55_23840  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
MJO55_23980  steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
MJO55_24045  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
MJO55_01240  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
MJO55_07715  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
MJO55_09025  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
MJO55_09040  thiolase family protein [KO:K00626] [EC:2.3.1.9]
MJO55_14245  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MJO55_16235  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MJO55_18785  thiolase family protein [KO:K00626] [EC:2.3.1.9]
MJO55_19540  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
MJO55_21175  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
MJO55_22210  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MJO55_19545  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
MJO55_06995  acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
MJO55_07185  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
MJO55_07180  acyl-CoA carboxylase subunit epsilon [KO:K27095]
MJO55_16910  acyl-CoA carboxylase subunit beta [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
MJO55_12515  mutA; methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
MJO55_12520  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
MJO55_19295  cobalamin B12-binding domain-containing protein [KO:K01849] [EC:5.4.99.2]
MJO55_19300  methylmalonyl-CoA mutase family protein [KO:K01848] [EC:5.4.99.2]
MJO55_20080  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
MJO55_25045  catalase [KO:K03781] [EC:1.11.1.6]
MJO55_15000  catalase [KO:K03781] [EC:1.11.1.6]
MJO55_16830  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
MJO55_25100  glnT; type III glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
MJO55_02020  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
MJO55_08330  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
MJO55_10270  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
MJO55_14375  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
MJO55_14890  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
MJO55_16695  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
MJO55_16740  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
MJO55_17625  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
MJO55_18170  glutamine synthetase III [KO:K01915] [EC:6.3.1.2]
MJO55_21060  glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
MJO55_13935  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
MJO55_16640  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
MJO55_03160  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
MJO55_13910  gcvH; glycine cleavage system protein GcvH [KO:K02437]
MJO55_18110  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
MJO55_16615  glycerate kinase [KO:K00865] [EC:2.7.1.165]
MJO55_27175  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
MJO55_22315  ketohydroxyglutarate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
MJO55_20145  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
MJO55_04620  cupin domain-containing protein [KO:K01569] [EC:4.1.1.2]
MJO55_04670  4Fe-4S dicluster domain-containing protein [KO:K00124]
MJO55_05175  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mrf00010  Glycolysis / Gluconeogenesis
mrf00020  Citrate cycle (TCA cycle)
mrf00030  Pentose phosphate pathway
mrf00053  Ascorbate and aldarate metabolism
mrf00071  Fatty acid degradation
mrf00230  Purine metabolism
mrf00250  Alanine, aspartate and glutamate metabolism
mrf00260  Glycine, serine and threonine metabolism
mrf00620  Pyruvate metabolism
mrf00710  Carbon fixation by Calvin cycle
mrf00750  Vitamin B6 metabolism
mrf00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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