KEGG   PATHWAY: mshg00230
Entry
mshg00230                   Pathway                                
Name
Purine metabolism - Mycobacterium shigaense
Class
Metabolism; Nucleotide metabolism
Pathway map
mshg00230  Purine metabolism
mshg00230

Module
mshg_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:mshg00230]
mshg_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:mshg00230]
mshg_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:mshg00230]
mshg_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:mshg00230]
mshg_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:mshg00230]
Other DBs
GO: 0006163 0042278
Organism
Mycobacterium shigaense [GN:mshg]
Gene
MSG_00426  nrdB; R2-like ligand binding oxidase [KO:K00526] [EC:1.17.4.1]
MSG_00584  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
MSG_00586  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
MSG_00713  [KO:K01524] [EC:3.6.1.11 3.6.1.40]
MSG_00956  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
MSG_01029  cyaA; adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
MSG_01039  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
MSG_01040  guaB3; putative oxidoreductase [KO:K00088] [EC:1.1.1.205]
MSG_01050  guaA; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
MSG_01054  [KO:K01239] [EC:3.2.2.1]
MSG_01115  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
MSG_01127  punA; purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
MSG_01160  purK; N5-carboxyaminoimidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
MSG_01161  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
MSG_01436  pgm; phosphoglucomutase, alpha-D-glucose phosphate-specific [KO:K01835] [EC:5.4.2.2]
MSG_01491  nrdE; ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
MSG_01504  nrdF; ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
MSG_01934  [KO:K19710] [EC:2.7.7.53]
MSG_01961  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
MSG_01962  relA; putative GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
MSG_02071  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
MSG_02284  cya; adenylate cyclase [KO:K01768] [EC:4.6.1.1]
MSG_02440  [KO:K01768] [EC:4.6.1.1]
MSG_02613  guaB1; putative oxidoreductase [KO:K26110]
MSG_02618  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
MSG_02619  ureB; urease subunit beta [KO:K01429] [EC:3.5.1.5]
MSG_02620  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
MSG_02905  [KO:K16841] [EC:5.1.99.3]
MSG_02907  [KO:K16842] [EC:3.5.2.5]
MSG_02908  alc; putative allantoicase [KO:K01477] [EC:3.5.3.4]
MSG_03040  [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
MSG_03095  adoK; adenosine kinase [KO:K00856] [EC:2.7.1.20]
MSG_03347  [KO:K01129] [EC:3.1.5.1]
MSG_03450  ndkA; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
MSG_03631  rdgB; non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
MSG_03703  cysNC; bifunctional enzyme CysN/CysC [KO:K00955] [EC:2.7.7.4 2.7.1.25]
MSG_03704  cysD; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
MSG_03730  [KO:K01768] [EC:4.6.1.1]
MSG_03819  [KO:K00957] [EC:2.7.7.4]
MSG_03820  [KO:K00955] [EC:2.7.7.4 2.7.1.25]
MSG_03929  [KO:K01768] [EC:4.6.1.1]
MSG_03985  [KO:K01524] [EC:3.6.1.11 3.6.1.40]
MSG_03990  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
MSG_03996  prs; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
MSG_04079  purH; bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
MSG_04080  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
MSG_04378  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
MSG_04379  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
MSG_04385  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269]
MSG_04408  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265]
MSG_04409  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264]
MSG_04416  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
MSG_04419  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
MSG_04424  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
MSG_04619  hpt; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
MSG_04634  [KO:K01768] [EC:4.6.1.1]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
mshg00030  Pentose phosphate pathway
mshg00220  Arginine biosynthesis
mshg00250  Alanine, aspartate and glutamate metabolism
mshg00260  Glycine, serine and threonine metabolism
mshg00340  Histidine metabolism
mshg00630  Glyoxylate and dicarboxylate metabolism
mshg00730  Thiamine metabolism
mshg00740  Riboflavin metabolism
mshg00790  Folate biosynthesis
KO pathway
ko00230   

DBGET integrated database retrieval system