KEGG   PATHWAY: mvm00230
Entry
mvm00230                    Pathway                                
Name
Purine metabolism - Mycolicibacter virginiensis
Class
Metabolism; Nucleotide metabolism
Pathway map
mvm00230  Purine metabolism
mvm00230

Module
mvm_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:mvm00230]
mvm_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:mvm00230]
mvm_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:mvm00230]
mvm_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:mvm00230]
mvm_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:mvm00230]
Other DBs
GO: 0006163 0042278
Organism
Mycolicibacter virginiensis [GN:mvm]
Gene
MJO54_05515  ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
MJO54_20055  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
MJO54_20200  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
MJO54_05085  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
MJO54_01895  purT; formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
MJO54_20075  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
MJO54_20100  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
MJO54_20095  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
MJO54_19985  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
MJO54_17175  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
MJO54_17170  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
MJO54_20135  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
MJO54_20155  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
MJO54_05090  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
MJO54_13170  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
MJO54_17735  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
MJO54_09800  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
MJO54_18265  nucleoside hydrolase [KO:K01239] [EC:3.2.2.1]
MJO54_21240  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
MJO54_18315  GuaB3 family IMP dehydrogenase-related protein [KO:K00088] [EC:1.1.1.205]
MJO54_18320  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
MJO54_08040  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
MJO54_07450  non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
MJO54_18295  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
MJO54_11105  GuaB1 family IMP dehydrogenase-related protein [KO:K26110] [EC:1.7.1.7]
MJO54_12870  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
MJO54_16050  nrdE; class 1b ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
MJO54_15935  nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
MJO54_15995  nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
MJO54_08710  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
MJO54_13165  RelA/SpoT family protein [KO:K01139] [EC:2.7.6.5 3.1.7.2]
MJO54_02845  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
MJO54_05580  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
MJO54_16985  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
MJO54_21390  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
MJO54_23395  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
MJO54_06980  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
MJO54_11955  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
MJO54_01875  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
MJO54_09550  carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
MJO54_17780  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
MJO54_18830  adenylate kinase [KO:K00939] [EC:2.7.4.3]
MJO54_05540  nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
MJO54_13370  HIT domain-containing protein [KO:K19710] [EC:2.7.7.53]
MJO54_07100  cysC; adenylyl-sulfate kinase [KO:K00955] [EC:2.7.7.4 2.7.1.25]
MJO54_07095  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
mvm00030  Pentose phosphate pathway
mvm00220  Arginine biosynthesis
mvm00250  Alanine, aspartate and glutamate metabolism
mvm00260  Glycine, serine and threonine metabolism
mvm00340  Histidine metabolism
mvm00630  Glyoxylate and dicarboxylate metabolism
mvm00730  Thiamine metabolism
mvm00740  Riboflavin metabolism
mvm00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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