KEGG   PATHWAY: nak00230
Entry
nak00230                    Pathway                                
Name
Purine metabolism - Nakamurella antarctica
Class
Metabolism; Nucleotide metabolism
Pathway map
nak00230  Purine metabolism
nak00230

Module
nak_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:nak00230]
nak_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:nak00230]
nak_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:nak00230]
nak_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:nak00230]
nak_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:nak00230]
Other DBs
GO: 0006163 0042278
Organism
Nakamurella antarctica [GN:nak]
Gene
EH165_05115  NUDIX hydrolase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
EH165_13750  alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
EH165_03380  ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
EH165_13800  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
EH165_13975  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
EH165_11175  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
EH165_13820  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
EH165_13830  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
EH165_13825  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
EH165_13795  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
EH165_10770  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
EH165_10765  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
EH165_13870  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
EH165_13895  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
EH165_11170  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
EH165_05800  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
EH165_13650  LPXTG cell wall anchor domain-containing protein [KO:K01081] [EC:3.1.3.5]
EH165_10910  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
EH165_04485  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
EH165_05400  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
EH165_11875  nucleoside hydrolase [KO:K25589] [EC:3.2.2.2 3.2.2.3]
EH165_12990  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
EH165_11370  GuaB3 family IMP dehydrogenase-related protein [KO:K00088] [EC:1.1.1.205]
EH165_11375  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
EH165_10230  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
EH165_09515  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
EH165_11350  glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
EH165_10505  guanylate kinase [KO:K00942] [EC:2.7.4.8]
EH165_03495  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
EH165_03500  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
EH165_08935  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
EH165_07780  dgt; dNTP triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
EH165_05805  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
EH165_03555  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
EH165_13365  hypothetical protein [KO:K01524] [EC:3.6.1.11 3.6.1.40]
EH165_09430  RelA/SpoT protein [KO:K07816] [EC:2.7.6.5]
EH165_14225  GTP pyrophosphokinase family protein [KO:K07816] [EC:2.7.6.5]
EH165_13980  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
EH165_06040  carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
EH165_11005  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
EH165_11800  hypothetical protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
EH165_11555  adenylate kinase [KO:K00939] [EC:2.7.4.3]
EH165_01025  phosphodiesterase [KO:K03651] [EC:3.1.4.53]
EH165_05725  HIT domain-containing protein [KO:K19710] [EC:2.7.7.53]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
nak00030  Pentose phosphate pathway
nak00220  Arginine biosynthesis
nak00250  Alanine, aspartate and glutamate metabolism
nak00260  Glycine, serine and threonine metabolism
nak00340  Histidine metabolism
nak00630  Glyoxylate and dicarboxylate metabolism
nak00730  Thiamine metabolism
nak00740  Riboflavin metabolism
nak00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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