KEGG   PATHWAY: oeu00053
Entry
oeu00053                    Pathway                                
Name
Ascorbate and aldarate metabolism - Olea europaea var. sylvestris (wild olive)
Class
Metabolism; Carbohydrate metabolism
Pathway map
oeu00053  Ascorbate and aldarate metabolism
oeu00053

Module
oeu_M00114  Ascorbate biosynthesis, plants, fructose-6P => ascorbate [PATH:oeu00053]
Other DBs
GO: 0019852 0019577 0019572
Organism
Olea europaea var. sylvestris (wild olive) [GN:oeu]
Gene
111400914  UDP-glucose 6-dehydrogenase 2-like [KO:K00012] [EC:1.1.1.22]
111374558  UDP-glucose 6-dehydrogenase 2-like [KO:K00012] [EC:1.1.1.22]
111374559  UDP-glucose 6-dehydrogenase 1 [KO:K00012] [EC:1.1.1.22]
111367179  UDP-glucose 6-dehydrogenase 2-like [KO:K00012] [EC:1.1.1.22]
111371758  UDP-glucose 6-dehydrogenase 3-like [KO:K00012] [EC:1.1.1.22]
111372378  UDP-glucose 6-dehydrogenase 1-like [KO:K00012] [EC:1.1.1.22]
111408714  UDP-sugar pyrophosphorylase-like isoform X1 [KO:K12447] [EC:2.7.7.64]
111397495  UDP-sugar pyrophosphorylase-like [KO:K12447] [EC:2.7.7.64]
111378060  glucuronokinase 1-like isoform X1 [KO:K16190] [EC:2.7.1.43]
111401541  inositol oxygenase 1-like isoform X1 [KO:K00469] [EC:1.13.99.1]
111374979  inositol oxygenase 5-like [KO:K00469] [EC:1.13.99.1]
111367291  inositol oxygenase 1-like [KO:K00469] [EC:1.13.99.1]
111366128  inositol oxygenase 2-like isoform X1 [KO:K00469] [EC:1.13.99.1]
111366233  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
111365892  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
111365893  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
111374761  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
111403232  aldose reductase [KO:K00002] [EC:1.1.1.2]
111379529  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
111391130  L-gulonolactone oxidase 3-like [KO:K00103] [EC:1.1.3.8]
111383576  GDP-mannose 3,5-epimerase 2 [KO:K10046] [EC:5.1.3.18 5.1.3.-]
111393710  GDP-mannose 3,5-epimerase 2-like [KO:K10046] [EC:5.1.3.18 5.1.3.-]
111376426  GDP-mannose 3,5-epimerase 2-like [KO:K10046] [EC:5.1.3.18 5.1.3.-]
111395119  GDP-L-galactose phosphorylase 2-like [KO:K14190] [EC:2.7.7.69]
111368795  GDP-L-galactose phosphorylase 2-like [KO:K14190] [EC:2.7.7.69]
111367355  GDP-L-galactose phosphorylase 1-like [KO:K14190] [EC:2.7.7.69]
111376502  GDP-L-galactose phosphorylase 2 isoform X1 [KO:K14190] [EC:2.7.7.69]
111379676  inositol-phosphate phosphatase-like isoform X1 [KO:K10047] [EC:3.1.3.25 3.1.3.93]
111408057  inositol monophosphatase 3-like [KO:K10047] [EC:3.1.3.25 3.1.3.93]
111370675  inositol-phosphate phosphatase-like [KO:K10047] [EC:3.1.3.25 3.1.3.93]
111412108  bifunctional phosphatase IMPL2, chloroplastic-like [KO:K18649] [EC:3.1.3.25 3.1.3.93 3.1.3.15]
111394577  bifunctional phosphatase IMPL2, chloroplastic-like [KO:K18649] [EC:3.1.3.25 3.1.3.93 3.1.3.15]
111388928  L-galactose dehydrogenase [KO:K17744] [EC:1.1.1.316]
111392244  L-galactono-1,4-lactone dehydrogenase, mitochondrial [KO:K00225] [EC:1.3.2.3]
111392814  UDP-glucuronate 4-epimerase 3-like [KO:K08679] [EC:5.1.3.6]
111390840  UDP-glucuronate 4-epimerase 6-like [KO:K08679] [EC:5.1.3.6]
111402322  UDP-glucuronate 4-epimerase 3-like [KO:K08679] [EC:5.1.3.6]
111378908  UDP-glucuronate 4-epimerase 3 [KO:K08679] [EC:5.1.3.6]
111373380  UDP-glucuronate 4-epimerase 3-like [KO:K08679] [EC:5.1.3.6]
111393982  UDP-glucuronate 4-epimerase 3-like [KO:K08679] [EC:5.1.3.6]
111396656  UDP-glucuronate 4-epimerase 6-like [KO:K08679] [EC:5.1.3.6]
111365981  UDP-glucuronate 4-epimerase 1-like [KO:K08679] [EC:5.1.3.6]
111402190  UDP-glucuronate 4-epimerase 1-like [KO:K08679] [EC:5.1.3.6]
111392695  UDP-glucuronate 4-epimerase 3-like [KO:K08679] [EC:5.1.3.6]
111382878  UDP-glucuronate 4-epimerase 3-like [KO:K08679] [EC:5.1.3.6]
111403724  UDP-glucuronate 4-epimerase 1-like [KO:K08679] [EC:5.1.3.6]
111399339  D-galacturonate reductase-like [KO:K19642] [EC:1.1.1.365]
111404068  monodehydroascorbate reductase [KO:K08232] [EC:1.6.5.4]
111409325  monodehydroascorbate reductase 4, peroxisomal-like [KO:K08232] [EC:1.6.5.4]
111412842  monodehydroascorbate reductase-like [KO:K08232] [EC:1.6.5.4]
111370734  monodehydroascorbate reductase-like isoform X1 [KO:K08232] [EC:1.6.5.4]
111376986  monodehydroascorbate reductase 4, peroxisomal-like [KO:K08232] [EC:1.6.5.4]
111390365  monodehydroascorbate reductase 4, peroxisomal-like [KO:K08232] [EC:1.6.5.4]
111407593  monodehydroascorbate reductase, chloroplastic/mitochondrial isoform X1 [KO:K08232] [EC:1.6.5.4]
111403155  L-ascorbate peroxidase 2, cytosolic [KO:K00434] [EC:1.11.1.11]
111372265  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial [KO:K00434] [EC:1.11.1.11]
111387515  putative L-ascorbate peroxidase 6 isoform X1 [KO:K00434] [EC:1.11.1.11]
111393231  L-ascorbate peroxidase 1, cytosolic [KO:K00434] [EC:1.11.1.11]
111374886  L-ascorbate peroxidase 3 [KO:K00434] [EC:1.11.1.11]
111399815  L-ascorbate peroxidase, cytosolic-like isoform X1 [KO:K00434] [EC:1.11.1.11]
111410119  L-ascorbate peroxidase 3-like [KO:K00434] [EC:1.11.1.11]
111369609  L-ascorbate peroxidase 1, cytosolic-like [KO:K00434] [EC:1.11.1.11]
111385880  glutathione S-transferase DHAR2-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
111389223  glutathione S-transferase DHAR2-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
111371401  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
111378276  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
111408228  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
111412906  L-ascorbate oxidase-like [KO:K00423] [EC:1.10.3.3]
111396530  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
111401958  aldehyde dehydrogenase family 3 member F1-like [KO:K00128] [EC:1.2.1.3]
111381845  aldehyde dehydrogenase-like [KO:K00128] [EC:1.2.1.3]
111381851  aldehyde dehydrogenase-like [KO:K00128] [EC:1.2.1.3]
111398887  aldehyde dehydrogenase family 2 member B7, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
111372266  aldehyde dehydrogenase-like [KO:K00128] [EC:1.2.1.3]
111373345  aldehyde dehydrogenase family 2 member B7, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
111373362  aldehyde dehydrogenase family 2 member B7, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
111402050  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
111411880  aldehyde dehydrogenase family 3 member F1-like [KO:K00128] [EC:1.2.1.3]
111392504  aldehyde dehydrogenase family 3 member F1-like [KO:K00128] [EC:1.2.1.3]
111405286  aldehyde dehydrogenase family 2 member B4, mitochondrial [KO:K00128] [EC:1.2.1.3]
111408706  aldehyde dehydrogenase-like [KO:K00128] [EC:1.2.1.3]
111402278  aldehyde dehydrogenase family 7 member B4 isoform X1 [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
Compound
C00022  Pyruvate
C00026  2-Oxoglutarate
C00029  UDP-glucose
C00072  Ascorbate
C00096  GDP-mannose
C00137  myo-Inositol
C00167  UDP-glucuronate
C00191  D-Glucuronate
C00216  D-Arabinose
C00231  D-Xylulose 5-phosphate
C00259  L-Arabinose
C00333  D-Galacturonate
C00433  2,5-Dioxopentanoate
C00545  L-Arabinonate
C00558  D-Tagaturonate
C00617  UDP-D-galacturonate
C00618  3-Dehydro-L-gulonate
C00652  D-Arabinono-1,4-lactone
C00679  5-Dehydro-4-deoxy-D-glucarate
C00684  2-Dehydro-3-deoxy-L-arabinonate
C00800  L-Gulonate
C00818  D-Glucarate
C00878  D-Arabinonate
C00879  D-Galactarate
C01040  L-Gulono-1,4-lactone
C01041  Monodehydroascorbate
C01101  L-Ribulose 5-phosphate
C01114  L-Arabinono-1,4-lactone
C01115  L-Galactono-1,4-lactone
C01146  2-Hydroxy-3-oxopropanoate
C01620  Threonate
C01825  L-Galactose
C02280  GDP-L-galactose
C02670  D-Glucuronolactone
C03033  beta-D-Glucuronoside
C03064  3-Dehydro-L-threonate
C03289  L-xylo-Hexulonolactone
C03291  L-Xylulose 5-phosphate
C03826  2-Dehydro-3-deoxy-D-xylonate
C03921  2-Dehydro-3-deoxy-D-glucarate
C04037  1-Phospho-alpha-D-galacturonate
C04575  (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate
C05385  D-Glucuronate 1-phosphate
C05411  L-Xylonate
C05412  L-Lyxonate
C05422  Dehydroascorbate
C06316  Dehydro-D-arabinono-1,4-lactone
C14899  3-Dehydro-L-gulonate 6-phosphate
C15923  L-Gulose
C15924  L-Gulose 1-phosphate
C15925  GDP-L-gulose
C15926  beta-L-Galactose 1-phosphate
C15930  L-Galactonate
C16186  L-Ascorbate 6-phosphate
C20889  D-Galactaro-1,5-lactone
C20896  D-Galactaro-1,4-lactone
C21955  L-Galactono-1,5-lactone
Reference
PMID:17222174
  Authors
Linster CL, Van Schaftingen E
  Title
Vitamin C. Biosynthesis, recycling and degradation in mammals.
  Journal
FEBS J 274:1-22 (2007)
DOI:10.1111/j.1742-4658.2006.05607.x
Reference
PMID:15564123
  Authors
Valpuesta V, Botella MA.
  Title
Biosynthesis of L-ascorbic acid in plants: new pathways for an old antioxidant.
  Journal
Trends Plant Sci 9:573-7 (2004)
DOI:10.1016/j.tplants.2004.10.002
Reference
PMID:10517845
  Authors
Davey MW, Gilot C, Persiau G, Ostergaard J, Han Y, Bauw GC, Van Montagu MC.
  Title
Ascorbate biosynthesis in Arabidopsis cell suspension culture.
  Journal
Plant Physiol 121:535-43 (1999)
DOI:10.1104/pp.121.2.535
Reference
PMID:16595667
  Authors
Conklin PL, Gatzek S, Wheeler GL, Dowdle J, Raymond MJ, Rolinski S, Isupov M, Littlechild JA, Smirnoff N.
  Title
Arabidopsis thaliana VTC4 encodes L-galactose-1-P phosphatase, a plant ascorbic acid biosynthetic enzyme.
  Journal
J Biol Chem 281:15662-70 (2006)
DOI:10.1074/jbc.M601409200
Reference
PMID:17462988
  Authors
Linster CL, Gomez TA, Christensen KC, Adler LN, Young BD, Brenner C, Clarke SG.
  Title
Arabidopsis VTC2 Encodes a GDP-L-Galactose Phosphorylase, the Last Unknown Enzyme in the Smirnoff-Wheeler Pathway to Ascorbic Acid in Plants.
  Journal
J Biol Chem 282:18879-85 (2007)
DOI:10.1074/jbc.M702094200
Reference
PMID:14996803
  Authors
Campos E, Baldoma L, Aguilar J, Badia J.
  Title
Regulation of expression of the divergent ulaG and ulaABCDEF operons involved in LaAscorbate dissimilation in Escherichia coli.
  Journal
J Bacteriol 186:1720-8 (2004)
DOI:10.1128/JB.186.6.1720-1728.2004
Reference
PMID:12644495
  Authors
Zhang Z, Aboulwafa M, Smith MH, Saier MH Jr.
  Title
The ascorbate transporter of Escherichia coli.
  Journal
J Bacteriol 185:2243-50 (2003)
DOI:10.1128/JB.185.7.2243-2250.2003
Related
pathway
oeu00020  Citrate cycle (TCA cycle)
oeu00040  Pentose and glucuronate interconversions
oeu00051  Fructose and mannose metabolism
oeu00520  Amino sugar and nucleotide sugar metabolism
oeu00630  Glyoxylate and dicarboxylate metabolism
KO pathway
ko00053   
LinkDB

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