KEGG   PATHWAY: abz00230
Entry
abz00230                    Pathway                                
Name
Purine metabolism - Acinetobacter baumannii MDR-ZJ06
Class
Metabolism; Nucleotide metabolism
Pathway map
abz00230  Purine metabolism
abz00230

Module
abz_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:abz00230]
abz_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:abz00230]
abz_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:abz00230]
abz_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:abz00230]
abz_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:abz00230]
abz_M00546  Purine degradation, xanthine => urea [PATH:abz00230]
abz_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:abz00230]
abz_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:abz00230]
Other DBs
GO: 0006163 0042278
Organism
Acinetobacter baumannii MDR-ZJ06 [GN:abz]
Gene
ABZJ_00300  NUDIX domain-containing protein [KO:K01515] [EC:3.6.1.13 3.6.1.-]
ABZJ_00878  phosphomannomutase/phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
ABZJ_00829  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
ABZJ_02050  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
ABZJ_02580  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
ABZJ_02542  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
ABZJ_03033  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
ABZJ_01674  formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
ABZJ_03011  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
ABZJ_03032  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
ABZJ_00027  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
ABZJ_00025  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
ABZJ_03811  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
ABZJ_02895  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
ABZJ_02541  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
ABZJ_01962  bifunctional metallophosphatase/5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
ABZJ_02887  5'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
ABZJ_02262  haloacid dehalogenase [KO:K20881] [EC:3.1.3.-]
ABZJ_00367  pyrimidine/purine nucleoside phosphorylase [KO:K09913] [EC:2.4.2.1 2.4.2.2]
ABZJ_00836  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
ABZJ_00015  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
ABZJ_03710  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
ABZJ_00539  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
ABZJ_00510  non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
ABZJ_03413  xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
ABZJ_02754  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
ABZJ_02753  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
ABZJ_00157  glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
ABZJ_02457  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
ABZJ_00016  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
ABZJ_01473  nucleoside deaminase [KO:K01487] [EC:3.5.4.3]
ABZJ_03557  guanylate kinase [KO:K00942] [EC:2.7.4.8]
ABZJ_00744  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
ABZJ_00742  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
ABZJ_03012  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
ABZJ_03559  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
ABZJ_00645  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
ABZJ_00617  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K00951] [EC:2.7.6.5]
ABZJ_04835  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
ABZJ_01316  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
ABZJ_00693  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
ABZJ_01306  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
ABZJ_01128  adenylate kinase [KO:K00939] [EC:2.7.4.3]
ABZJ_00619  nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
ABZJ_00299  3',5'-cyclic-AMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
ABZJ_03380  symmetrical bis(5'-nucleosyl)-tetraphosphatase [KO:K01525] [EC:3.6.1.41]
ABZJ_01106  cysN; sulfate adenylyltransferase subunit CysN [KO:K00956] [EC:2.7.7.4]
ABZJ_01105  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
ABZJ_03745  hpxO; FAD-dependent urate hydroxylase HpxO [KO:K16839] [EC:1.14.13.113]
ABZJ_03742  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
ABZJ_03741  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
ABZJ_01646  aspartate/glutamate racemase family protein [KO:K16841] [EC:5.1.99.3]
ABZJ_03740  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
ABZJ_03746  allantoicase [KO:K01477] [EC:3.5.3.4]
ABZJ_03747  ureidoglycolate lyase [KO:K01483] [EC:4.3.2.3]
ABZJ_01119  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
ABZJ_01118  urease subunit beta [KO:K01429] [EC:3.5.1.5]
ABZJ_01117  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
abz00030  Pentose phosphate pathway
abz00220  Arginine biosynthesis
abz00250  Alanine, aspartate and glutamate metabolism
abz00260  Glycine, serine and threonine metabolism
abz00340  Histidine metabolism
abz00630  Glyoxylate and dicarboxylate metabolism
abz00730  Thiamine metabolism
abz00740  Riboflavin metabolism
abz00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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