KEGG   PATHWAY: ache00100
Entry
ache00100                   Pathway                                
Name
Steroid biosynthesis - Aspergillus chevalieri
Class
Metabolism; Lipid metabolism
Pathway map
ache00100  Steroid biosynthesis
ache00100

Module
ache_M00102  Ergocalciferol biosynthesis, FPP => ergosterol/ergocalciferol [PATH:ache00100]
Other DBs
GO: 0016126
Organism
Aspergillus chevalieri [GN:ache]
Gene
ACHE_70882S  ERG9; bifunctional farnesyl-diphosphate farnesyltransferase/squalene synthase [KO:K00801] [EC:2.5.1.21]
ACHE_21335S  ERG1; squalene epoxidase [KO:K00511] [EC:1.14.14.17]
ACHE_60781A  ERG7; lanosterol synthase (oxidosqualene--lanosterol cyclase) [KO:K01852] [EC:5.4.99.7]
ACHE_70438A  ERG11_2; lanosterol 14-alpha-demethylase [KO:K05917] [EC:1.14.14.154 1.14.15.36]
ACHE_40252S  ERG11_1; lanosterol 14-alpha-demethylase [KO:K05917] [EC:1.14.14.154 1.14.15.36]
ACHE_10917S  ERG24; erg24, C-14 sterol reductase [KO:K00222] [EC:1.3.1.70]
ACHE_80507A  ERG3_2; C-5 sterol desaturase [KO:K00222] [EC:1.3.1.70]
ACHE_31017A  ERG25; C-4 sterol methyl oxidase [KO:K07750] [EC:1.14.18.9]
ACHE_31358A  ERG26_2; erg26, C-3 sterol dehydrogenase [KO:K07748] [EC:1.1.1.170]
ACHE_10583S  ERG27; 3-keto-steroid reductase [KO:K09827] [EC:1.1.1.270]
ACHE_70181S  uncharacterized protein [KO:K01824] [EC:5.3.3.5]
ACHE_30670S  uncharacterized protein [KO:K01824] [EC:5.3.3.5]
ACHE_20394S  uncharacterized protein [KO:K00227] [EC:1.14.19.20]
ACHE_50257A  ERG3_1; C-5 sterol desaturase [KO:K00227] [EC:1.14.19.20]
ACHE_50598A  TGL1; cholesterol esterase [KO:K01052] [EC:3.1.1.13]
ACHE_11056S  uncharacterized protein [KO:K00637] [EC:2.3.1.26]
ACHE_60580A  ERG6; delta(24)-sterol C-methyltransferase [KO:K00559] [EC:2.1.1.41]
ACHE_40345A  uncharacterized protein [KO:K00559] [EC:2.1.1.41]
ACHE_11623A  ERG2; C-8 sterol isomerase [KO:K09829] [EC:5.-.-.-]
ACHE_11570S  ERG5; RNA polymerase C-22 sterol desaturase [KO:K09831] [EC:1.14.19.41]
ACHE_11303S  ERG4_1; C-24(28) sterol reductase [KO:K00223] [EC:1.3.1.71]
ACHE_80094A  ERG4_2; C-24(28) sterol reductase [KO:K00223] [EC:1.3.1.71]
Compound
C00187  Cholesterol
C00448  trans,trans-Farnesyl diphosphate
C00751  Squalene
C01054  (S)-2,3-Epoxysqualene
C01164  7-Dehydrocholesterol
C01189  Lathosterol
C01561  Calcidiol
C01673  Calcitriol
C01694  Ergosterol
C01724  Lanosterol
C01753  beta-Sitosterol
C01789  Campesterol
C01802  Desmosterol
C01902  Cycloartenol
C01943  Obtusifoliol
C02141  Cycloeucalenol
C02530  Cholesterol ester
C03428  Presqualene diphosphate
C03845  5alpha-Cholest-8-en-3beta-ol
C04525  Fecosterol
C05103  4alpha-Methylzymosterol
C05107  7-Dehydrodesmosterol
C05108  14-Demethyllanosterol
C05109  24,25-Dihydrolanosterol
C05437  Zymosterol
C05439  5alpha-Cholesta-7,24-dien-3beta-ol
C05440  Ergosta-5,7,22,24(28)-tetraen-3beta-ol
C05441  Vitamin D2
C05442  Stigmasterol
C05443  Vitamin D3
C07712  Secalciferol
C08813  Brassicasterol
C08821  Isofucosterol
C08830  24-Methylidenecycloartanol
C11455  4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol
C11508  4alpha-Methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol
C11522  24-Methylenelophenol
C11523  24-Ethylidenelophenol
C15776  4alpha-Methylfecosterol
C15777  Episterol
C15780  5-Dehydroepisterol
C15781  24-Methylenecholesterol
C15782  Delta7-Avenasterol
C15783  5-Dehydroavenasterol
C15808  4alpha-Methylzymosterol-4-carboxylate
C15816  3-Keto-4-methylzymosterol
C15915  4,4-Dimethyl-5alpha-cholesta-8-en-3beta-ol
C18231  Calcitetrol
C21106  24-epi-Campesterol
C22112  4alpha-Carboxy-5alpha-cholesta-8,24-dien-3beta-ol
C22116  3beta-Hydroxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-4alpha-carboxylate
C22119  3beta-Hydroxyergosta-7,24(24(1))-dien-4alpha-carboxylate
C22120  4alpha-Carboxy-stigmasta-7,24(24(1))-dien-3beta-ol
C22121  Cycloeucalenone
C22122  Episterone
C22123  Avenastenone
C22136  Zymosterone
Reference
  Authors
Koshiba K, Kamiya Y.
  Title
[Atarasii Syokubutuhorumon no Kagaku] (In Japanese)
  Journal
Koudansya saientific:199-138 (2002)
Reference
  Authors
Morikawa T, Mizutani M, Aoki N, Watanabe B, Saga H, Saito S, Oikawa A, Suzuki H, Sakurai N, Shibata D, Wadano A, Sakata K, Ohta D.
  Title
Cytochrome P450 CYP710A encodes the sterol C-22 desaturase in Arabidopsis and tomato.
  Journal
Plant Cell 18:1008-22 (2006)
DOI:10.1105/tpc.105.036012
Reference
  Authors
Lange BM, Ghassemian M.
  Title
Genome organization in Arabidopsis thaliana: a survey for genes involved in isoprenoid and chlorophyll metabolism.
  Journal
Plant Mol Biol 51:925-48 (2003)
DOI:10.1023/A:1023005504702
Related
pathway
ache00900  Terpenoid backbone biosynthesis
KO pathway
ko00100   
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