KEGG   PATHWAY: amau00230
Entry
amau00230                   Pathway                                
Name
Purine metabolism - Agromyces marinus
Class
Metabolism; Nucleotide metabolism
Pathway map
amau00230  Purine metabolism
amau00230

Module
amau_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:amau00230]
amau_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:amau00230]
amau_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:amau00230]
amau_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:amau00230]
amau_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:amau00230]
amau_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:amau00230]
Other DBs
GO: 0006163 0042278
Organism
Agromyces marinus [GN:amau]
Gene
DSM26151_02650  pgm; Phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
DSM26151_20680  prs; Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
DSM26151_26950  purF; Amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
DSM26151_26990  purD; Phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
DSM26151_22710  purN; Phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
DSM26151_27210  purL; Phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
DSM26151_27090  purS; Phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
DSM26151_27100  purQ; Phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
DSM26151_26910  purM; Phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
DSM26151_08850  purK; N5-carboxyaminoimidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
DSM26151_08860  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
DSM26151_27000  purC; Phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
DSM26151_29930  purB; Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
DSM26151_22700  purH; Bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
DSM26151_27190  apt; Adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
DSM26151_24710  yhcR; Endonuclease YhcR [KO:K01081] [EC:3.1.3.5]
DSM26151_27580  hdpA; Dihydroxyacetone phosphatase [KO:K02566] [EC:3.1.3.5]
DSM26151_08700  punA; Purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
DSM26151_27670  rihA; Pyrimidine-specific ribonucleoside hydrolase RihA [KO:K25589] [EC:3.2.2.2 3.2.2.3]
DSM26151_24320  hpt; Hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
DSM26151_23000  putative oxidoreductase/MSMEI_1564 [KO:K00088] [EC:1.1.1.205]
DSM26151_23030  guaB; Inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
DSM26151_15600  ndkA; Nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
DSM26151_19170  dITP/XTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
DSM26151_07290  hypothetical protein [KO:K13481] [EC:1.17.1.4]
DSM26151_07280  mop; Aldehyde oxidoreductase [KO:K13482] [EC:1.17.1.4]
DSM26151_22940  guaA; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
DSM26151_24020  hypothetical protein [KO:K01951] [EC:6.3.5.2]
DSM26151_26930  hypothetical protein [KO:K01951] [EC:6.3.5.2]
DSM26151_03050  hypothetical protein [KO:K01951] [EC:6.3.5.2]
DSM26151_09680  guaB1; putative oxidoreductase [KO:K26110] [EC:1.7.1.7]
DSM26151_16190  gmk; Guanylate kinase [KO:K00942] [EC:2.7.4.8]
DSM26151_05350  nrdE2; Ribonucleoside-diphosphate reductase subunit alpha 2 [KO:K00525] [EC:1.17.4.1]
DSM26151_05360  nrdF2; Ribonucleoside-diphosphate reductase subunit beta nrdF2 [KO:K00526] [EC:1.17.4.1]
DSM26151_04490  Deoxyguanosinetriphosphate triphosphohydrolase-like protein [KO:K01129] [EC:3.1.5.1]
DSM26151_13680  dgt; Deoxyguanosinetriphosphate triphosphohydrolase-like protein [KO:K01129] [EC:3.1.5.1]
DSM26151_16460  relA; Bifunctional (p)ppGpp synthase/hydrolase RelA [KO:K01139] [EC:2.7.6.5 3.1.7.2]
DSM26151_20450  ppx1; Exopolyphosphatase 1 [KO:K01524] [EC:3.6.1.11 3.6.1.40]
DSM26151_12680  ywaC; GTP pyrophosphokinase YwaC [KO:K07816] [EC:2.7.6.5]
DSM26151_05440  hypothetical protein [KO:K01768] [EC:4.6.1.1]
DSM26151_09520  hypothetical protein [KO:K01768] [EC:4.6.1.1]
DSM26151_27430  purA; Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
DSM26151_08670  add; Adenosine deaminase [KO:K01488] [EC:3.5.4.4]
DSM26151_23350  adk; Adenylate kinase [KO:K00939] [EC:2.7.4.3]
DSM26151_17590  cpdA; 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [KO:K03651] [EC:3.1.4.53]
DSM26151_16590  AP-4-A phosphorylase [KO:K19710] [EC:2.7.7.53]
DSM26151_28870  cysNC; Bifunctional enzyme CysN/CysC [KO:K00956] [EC:2.7.7.4]
DSM26151_28860  cysD; Sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
DSM26151_07360  uox; Uricase [KO:K00365] [EC:1.7.3.3]
DSM26151_07350  hiuH; 5-hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
DSM26151_07340  hypothetical protein [KO:K16840] [EC:4.1.1.97]
DSM26151_07330  allB; Allantoinase [KO:K01466] [EC:3.5.2.5]
DSM26151_07320  allE; (S)-ureidoglycine aminohydrolase [KO:K14977] [EC:3.5.3.26]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
amau00030  Pentose phosphate pathway
amau00220  Arginine biosynthesis
amau00250  Alanine, aspartate and glutamate metabolism
amau00260  Glycine, serine and threonine metabolism
amau00340  Histidine metabolism
amau00630  Glyoxylate and dicarboxylate metabolism
amau00730  Thiamine metabolism
amau00740  Riboflavin metabolism
amau00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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