KEGG   PATHWAY: asub00230
Entry
asub00230                   Pathway                                
Name
Purine metabolism - Atlantibacter subterranea
Class
Metabolism; Nucleotide metabolism
Pathway map
asub00230  Purine metabolism
asub00230

Module
asub_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:asub00230]
asub_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:asub00230]
asub_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:asub00230]
asub_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:asub00230]
asub_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:asub00230]
asub_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:asub00230]
asub_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:asub00230]
Other DBs
GO: 0006163 0042278
Organism
Atlantibacter subterranea [GN:asub]
Gene
NLZ15_18650  nudF; ADP-ribose diphosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
NLZ15_01565  nudE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
NLZ15_19075  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
NLZ15_07060  pgm; phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) [KO:K01835] [EC:5.4.2.2]
NLZ15_09295  prs; ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
NLZ15_15495  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
NLZ15_20825  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
NLZ15_16165  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
NLZ15_12955  purT; formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
NLZ15_05625  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
NLZ15_16160  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
NLZ15_05825  purK; 5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
NLZ15_05830  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
NLZ15_16105  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
NLZ15_12455  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
NLZ15_20820  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
NLZ15_05665  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
NLZ15_05715  ushA; bifunctional UDP-sugar hydrolase/5'-nucleotidase UshA [KO:K11751] [EC:3.1.3.5 3.6.1.45]
NLZ15_04355  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
NLZ15_07000  HAD-IIA family hydrolase [KO:K02566] [EC:3.1.3.5]
NLZ15_01555  yrfG; GMP/IMP nucleotidase [KO:K20881] [EC:3.1.3.-]
NLZ15_05700  inosine/guanosine kinase [KO:K00892] [EC:2.7.1.73]
NLZ15_15835  xapA; xanthosine phosphorylase [KO:K03783] [EC:2.4.2.1]
NLZ15_19070  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
NLZ15_16810  ppnP; pyrimidine/purine nucleoside phosphorylase [KO:K09913] [EC:2.4.2.1 2.4.2.2]
NLZ15_05435  yfiH; purine nucleoside phosphorylase YfiH [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
NLZ15_18160  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
NLZ15_16195  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
NLZ15_16245  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
NLZ15_02825  yjjX; inosine/xanthosine triphosphatase [KO:K01529] [EC:3.6.1.73]
NLZ15_03500  XTP/dITP diphosphatase [KO:K01519] [EC:3.6.1.66]
NLZ15_17660  gpt; xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
NLZ15_03890  xdhA; xanthine dehydrogenase molybdenum-binding subunit XdhA [KO:K00087] [EC:1.17.1.4]
NLZ15_03885  xdhB; xanthine dehydrogenase FAD-binding subunit XdhB [KO:K13479] [EC:1.17.1.4]
NLZ15_03880  xdhC; xanthine dehydrogenase iron sulfur-binding subunit XdhC [KO:K13480]
NLZ15_11095  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
NLZ15_11090  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
NLZ15_11085  paoA; aldehyde dehydrogenase iron-sulfur subunit [KO:K13483]
NLZ15_16190  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
NLZ15_10600  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
NLZ15_18290  GMP reductase [KO:K00364] [EC:1.7.1.7]
NLZ15_03805  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
NLZ15_21890  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
NLZ15_04530  nrdE; class 1b ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
NLZ15_15180  nrdA; ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
NLZ15_04525  nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
NLZ15_15185  nrdB; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
NLZ15_02385  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
NLZ15_18010  dgt; dGTPase [KO:K01129] [EC:3.1.5.1]
NLZ15_15375  yfbR; 5'-deoxynucleotidase [KO:K08722] [EC:3.1.3.89]
NLZ15_21900  spoT; bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
NLZ15_16175  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
NLZ15_21355  gppA; guanosine-5'-triphosphate,3'-diphosphate diphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
NLZ15_04250  relA; GTP diphosphokinase [KO:K00951] [EC:2.7.6.5]
NLZ15_21240  cyaA; class I adenylate cyclase [KO:K05851] [EC:4.6.1.1]
NLZ15_19985  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
NLZ15_11710  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
NLZ15_08095  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
NLZ15_04160  ppnN; nucleotide 5'-monophosphate nucleosidase PpnN [KO:K06966] [EC:3.2.2.10 3.2.2.-]
NLZ15_07565  adeD; adenine deaminase [KO:K01486] [EC:3.5.4.2]
NLZ15_19870  bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
NLZ15_05690  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
NLZ15_04255  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
NLZ15_18640  cpdA; 3',5'-cyclic-AMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
NLZ15_03260  apaH; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH [KO:K01525] [EC:3.6.1.41]
NLZ15_04325  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
NLZ15_04320  cysN; sulfate adenylyltransferase subunit CysN [KO:K00956] [EC:2.7.7.4]
NLZ15_04315  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
NLZ15_17740  alanine--glyoxylate aminotransferase family protein [KO:K00839] [EC:2.6.1.112]
NLZ15_03850  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
NLZ15_00690  carbamate kinase [KO:K00926] [EC:2.7.2.2]
NLZ15_07980  carbamate kinase family protein [KO:K00926] [EC:2.7.2.2]
NLZ15_09865  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
asub00030  Pentose phosphate pathway
asub00220  Arginine biosynthesis
asub00250  Alanine, aspartate and glutamate metabolism
asub00260  Glycine, serine and threonine metabolism
asub00340  Histidine metabolism
asub00630  Glyoxylate and dicarboxylate metabolism
asub00730  Thiamine metabolism
asub00740  Riboflavin metabolism
asub00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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