KEGG   PATHWAY: bsk00230
Entry
bsk00230                    Pathway                                
Name
Purine metabolism - Brucella canis HSK A52141
Class
Metabolism; Nucleotide metabolism
Pathway map
bsk00230  Purine metabolism
bsk00230

Module
bsk_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:bsk00230]
bsk_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bsk00230]
bsk_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bsk00230]
bsk_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bsk00230]
bsk_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bsk00230]
bsk_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:bsk00230]
bsk_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:bsk00230]
Other DBs
GO: 0006163 0042278
Organism
Brucella canis HSK A52141 [GN:bsk]
Gene
BCA52141_I1607  Phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
BCA52141_I2734  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
BCA52141_I0978  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
BCA52141_I1028  phosphoribosylamine-glycine ligase [KO:K01945] [EC:6.3.4.13]
BCA52141_I0590  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
BCA52141_I0388  phosphoribosylformylglycinamidine synthase II [KO:K23269] [EC:6.3.5.3]
BCA52141_I0380  phosphoribosylformylglycinamidine synthase, purS protein [KO:K23264] [EC:6.3.5.3]
BCA52141_I0382  phosphoribosylformylglycinamidine synthase 1 [KO:K23265] [EC:6.3.5.3 3.5.1.2]
BCA52141_I0589  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
BCA52141_I2401  phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
BCA52141_I2404  phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
BCA52141_I0377  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
BCA52141_I0369  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
BCA52141_I2294  bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
BCA52141_I2721  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
BCA52141_I0313  acid phosphatase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
BCA52141_I2738  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
BCA52141_I2029  Hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
BCA52141_II0698  inosine-5''-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
BCA52141_I0617  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
BCA52141_I1412  Ham1 family protein [KO:K01519] [EC:3.6.1.66]
BCA52141_I0057  xanthine-guanine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
BCA52141_I1127  xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
BCA52141_I1125  xanthine dehydrogenase [KO:K13482] [EC:1.17.1.4]
BCA52141_II0686  GMP synthase [KO:K01951] [EC:6.3.5.2]
BCA52141_I1117  guanine deaminase [KO:K01487] [EC:3.5.4.3]
BCA52141_I0948  guanylate kinase [KO:K00942] [EC:2.7.4.8]
BCA52141_II0741  ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
BCA52141_I0062  ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent [KO:K00525] [EC:1.17.4.1]
BCA52141_II0739  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
BCA52141_I0329  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
BCA52141_I0656  putative hydrolases of HD superfamily [KO:K06952] [EC:3.1.3.89]
BCA52141_I0678  RelA/SpoT family protein [KO:K01139] [EC:2.7.6.5 3.1.7.2]
BCA52141_I0533  ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
BCA52141_II0256  Ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
BCA52141_I2508  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
BCA52141_I0710  Nucleoside phosphorylase [KO:K01241] [EC:3.2.2.4]
BCA52141_I2441  hypothetical protein [KO:K09769] [EC:3.1.4.16]
BCA52141_I3234  adenylate kinase [KO:K00939] [EC:2.7.4.3]
BCA52141_I0027  nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
BCA52141_I1379  sulfate adenylyltransferase [KO:K00955] [EC:2.7.7.4 2.7.1.25]
BCA52141_I1380  sulfate adenylyltransferase, small subunit [KO:K00957] [EC:2.7.7.4]
BCA52141_I0873  hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
BCA52141_I1130  chitin deacetylase [KO:K16842] [EC:3.5.2.5]
BCA52141_I1131  allantoin catabolism protein [KO:K14977] [EC:3.5.3.26]
BCA52141_I0874  ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
BCA52141_I1256  urease, alpha subunit [KO:K01428] [EC:3.5.1.5]
BCA52141_I3009  UreC, Urea amidohydrolase (urease) alpha subunit [KO:K01428] [EC:3.5.1.5]
BCA52141_I1257  urease, beta subunit [KO:K01429] [EC:3.5.1.5]
BCA52141_I3010  urease [KO:K01429] [EC:3.5.1.5]
BCA52141_I1260  UreA, Urea amidohydrolase (urease) gamma subunit [KO:K01430] [EC:3.5.1.5]
BCA52141_I3012  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
bsk00030  Pentose phosphate pathway
bsk00220  Arginine biosynthesis
bsk00250  Alanine, aspartate and glutamate metabolism
bsk00260  Glycine, serine and threonine metabolism
bsk00340  Histidine metabolism
bsk00630  Glyoxylate and dicarboxylate metabolism
bsk00730  Thiamine metabolism
bsk00740  Riboflavin metabolism
bsk00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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