KEGG   PATHWAY: cdr00230
Entry
cdr00230                    Pathway                                
Name
Purine metabolism - Corynebacterium diphtheriae HC03
Class
Metabolism; Nucleotide metabolism
Pathway map
cdr00230  Purine metabolism
cdr00230

Module
cdr_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:cdr00230]
cdr_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:cdr00230]
cdr_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:cdr00230]
cdr_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:cdr00230]
cdr_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:cdr00230]
Other DBs
GO: 0006163 0042278
Organism
Corynebacterium diphtheriae HC03 [GN:cdr]
Gene
CDHC03_1765  pgm; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
CDHC03_0808  prsA; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
CDHC03_1801  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
CDHC03_1814  purD; phosphoribosylamine-glycine ligase [KO:K01945] [EC:6.3.4.13]
CDHC03_0751  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
CDHC03_1938  purT; phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
CDHC03_2023  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
CDHC03_1800  purM; phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
CDHC03_0587  purK; phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
CDHC03_0588  purE; phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
CDHC03_1809  purC; phosphoribosylaminoimidazole-succinocarboxamidesynthase [KO:K01923] [EC:6.3.2.6]
CDHC03_1810  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
CDHC03_0752  purH; bifunctionalphosphoribosylaminoimidazolecarboxam ide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
CDHC03_1275  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
CDHC03_1591  putative N-acetylglucosamine related protein [KO:K02566] [EC:3.1.3.5]
CDHC03_0204  deoD; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
CDHC03_1506  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
CDHC03_2229  putative nucleoside hydrolase [KO:K01239] [EC:3.2.2.1]
CDHC03_1654  iunH; inosine-uridine preferring nucleoside hydrolase [KO:K25589] [EC:3.2.2.2 3.2.2.3]
CDHC03_1877  hpt; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
CDHC03_0504  guaB; inosine 5-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
CDHC03_0505  inosine 5-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
CDHC03_1682  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
CDHC03_1736  putative deoxyribonucleotide triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
CDHC03_0518  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
CDHC03_1189  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
CDHC03_1231  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
CDHC03_1753  nrdE; ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
CDHC03_1751  nrdF1; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
CDHC03_1805  nrdF2; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
CDHC03_0389  anaerobic ribonucleoside triphosphate reductase [KO:K21636] [EC:1.1.98.6]
CDHC03_1601  dgt; deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
CDHC03_1274  rel; GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
CDHC03_0825  ppx2; putative exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
CDHC03_0265  cya; adenylate cyclase [KO:K01768] [EC:4.6.1.1]
CDHC03_1944  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
CDHC03_0563  hypothetical protein [KO:K01488] [EC:3.5.4.4]
CDHC03_0465  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
CDHC03_1308  hypothetical protein [KO:K19710] [EC:2.7.7.53]
CDHC03_2194  hypothetical protein [KO:K19710] [EC:2.7.7.53]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
cdr00030  Pentose phosphate pathway
cdr00220  Arginine biosynthesis
cdr00250  Alanine, aspartate and glutamate metabolism
cdr00260  Glycine, serine and threonine metabolism
cdr00340  Histidine metabolism
cdr00630  Glyoxylate and dicarboxylate metabolism
cdr00730  Thiamine metabolism
cdr00740  Riboflavin metabolism
cdr00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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