KEGG   PATHWAY: cgl00230
Entry
cgl00230                    Pathway                                
Name
Purine metabolism - Corynebacterium glutamicum ATCC 13032 (Kyowa Hakko)
Class
Metabolism; Nucleotide metabolism
Pathway map
cgl00230  Purine metabolism
cgl00230

Module
cgl_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:cgl00230]
cgl_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:cgl00230]
cgl_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:cgl00230]
cgl_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:cgl00230]
cgl_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:cgl00230]
Other DBs
GO: 0006163 0042278
Organism
Corynebacterium glutamicum ATCC 13032 (Kyowa Hakko) [GN:cgl]
Gene
Cgl2541  Cgl2541; Phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
Cgl0942  Cgl0942; Phosphoribosylpyrophosphate synthetase [KO:K00948] [EC:2.7.6.1]
Cgl2584  Cgl2584; Glutamine phosphoribosylpyrophosphate amidotransferase [KO:K00764] [EC:2.4.2.14]
Cgl2600  Cgl2600; Phosphoribosylamine-glycine ligase [KO:K01945] [EC:6.3.4.13]
Cgl0860  Cgl0860; Folate-dependent phosphoribosylglycinamide formyltransferase PurN [KO:K11175] [EC:2.1.2.2]
Cgl2759  Cgl2759; Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) [KO:K08289] [EC:6.3.1.21]
Cgl2588  Cgl2588; Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain [KO:K23269] [EC:6.3.5.3]
Cgl2590  Cgl2590; Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component [KO:K23264] [EC:6.3.5.3]
Cgl2589  Cgl2589; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain [KO:K23265] [EC:6.3.5.3 3.5.1.2]
Cgl2583  Cgl2583; Phosphoribosylaminoimidazol (AIR) synthetase [KO:K01933] [EC:6.3.3.1]
Cgl0711  Cgl0711; Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) [KO:K01589] [EC:6.3.4.18]
Cgl0714  Cgl0714; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [KO:K01588] [EC:5.4.99.18]
Cgl2597  Cgl2597; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase [KO:K01923] [EC:6.3.2.6]
Cgl2598  Cgl2598; Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
Cgl0861  Cgl0861; AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) [KO:K00602] [EC:2.1.2.3 3.5.4.10]
Cgl1654  Cgl1654; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins [KO:K00759] [EC:2.4.2.7]
Cgl0023  Cgl0023; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [KO:K01081] [EC:3.1.3.5]
Cgl0328  Cgl0328; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [KO:K01081] [EC:3.1.3.5]
Cgl2256  Cgl2256; Predicted sugar phosphatases of the HAD superfamily [KO:K02566] [EC:3.1.3.5]
Cgl2154  Cgl2154; Uncharacterized ACR [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
Cgl2835  Cgl2835; Inosine-uridine nucleoside N-ribohydrolase [KO:K01239] [EC:3.2.2.1]
Cgl1364  Cgl1364; Inosine-uridine nucleoside N-ribohydrolase [KO:K25589] [EC:3.2.2.2 3.2.2.3]
Cgl2697  Cgl2697; Hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
Cgl0603  Cgl0603; IMP dehydrogenase/GMP reductase [KO:K00088] [EC:1.1.1.205]
Cgl0604  Cgl0604; IMP dehydrogenase/GMP reductase [KO:K00088] [EC:1.1.1.205]
Cgl2370  Cgl2370; Nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
Cgl2500  Cgl2500; Xanthosine triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
Cgl0607  Cgl0607; GMP synthase - PP-ATPase domain [KO:K01951] [EC:6.3.5.2]
Cgl1542  Cgl1542; GMP synthase - Glutamine amidotransferase domain [KO:K01951] [EC:6.3.5.2]
Cgl2679  Cgl2679; IMP dehydrogenase/GMP reductase [KO:K26110] [EC:1.7.1.7]
Cgl1606  Cgl1606; Guanylate kinase [KO:K00942] [EC:2.7.4.8]
Cgl2530  Cgl2530; Ribonucleotide reductase alpha subunit [KO:K00525] [EC:1.17.4.1]
Cgl2525  Cgl2525; Ribonucleotide reductase beta subunit [KO:K00526] [EC:1.17.4.1]
Cgl2273  Cgl2273; dGTP triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
Cgl1653  Cgl1653; Guanosine polyphosphate pyrophosphohydrolases/synthetases [KO:K01139] [EC:2.7.6.5 3.1.7.2]
Cgl0408  Cgl0408; Exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Cgl0977  Cgl0977; Exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Cgl1177  Cgl1177; Uncharacterized BCR [KO:K07816] [EC:2.7.6.5]
Cgl0311  Cgl0311; Adenylate cyclase, family 3 (some proteins contain HAMP domain) [KO:K01768] [EC:4.6.1.1]
Cgl2766  Cgl2766; Adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
Cgl0095  Cgl0095; Nucleoside phosphorylase [KO:K01241] [EC:3.2.2.4]
Cgl0556  Cgl0556; Adenylate kinase and related kinases [KO:K00939] [EC:2.7.4.3]
Cgl1670  Cgl1670; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [KO:K19710] [EC:2.7.7.53]
Cgl2814  Cgl2814; GTPases - Sulfate adenylate transferase subunit 1 [KO:K00956] [EC:2.7.7.4]
Cgl2815  Cgl2815; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [KO:K00957] [EC:2.7.7.4]
Cgl0086  Cgl0086; Urea amidohydrolase (urease) alpha subunit [KO:K01428] [EC:3.5.1.5]
Cgl0085  Cgl0085; Urea amidohydrolase (urease) beta subunit [KO:K01429] [EC:3.5.1.5]
Cgl0084  Cgl0084; Urea amidohydrolase (urease) gamma subunit [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
cgl00030  Pentose phosphate pathway
cgl00220  Arginine biosynthesis
cgl00250  Alanine, aspartate and glutamate metabolism
cgl00260  Glycine, serine and threonine metabolism
cgl00340  Histidine metabolism
cgl00630  Glyoxylate and dicarboxylate metabolism
cgl00730  Thiamine metabolism
cgl00740  Riboflavin metabolism
cgl00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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