KEGG   PATHWAY: dwd00630
Entry
dwd00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Desulfosarcina widdelii
Class
Metabolism; Carbohydrate metabolism
Pathway map
dwd00630  Glyoxylate and dicarboxylate metabolism
dwd00630

Module
dwd_M00012  Glyoxylate cycle [PATH:dwd00630]
dwd_M00621  Glycine cleavage system [PATH:dwd00630]
Other DBs
GO: 0046487 0043648
Organism
Desulfosarcina widdelii [GN:dwd]
Gene
DSCW_20600  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
DSCW_00440  acsA_1; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DSCW_20350  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
DSCW_20370  acsA_2; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DSCW_52520  acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DSCW_17450  acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DSCW_49550  acsA_3; acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
DSCW_09890  acs; acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
DSCW_20590  malate synthase [KO:K01638] [EC:2.3.3.9]
DSCW_09970  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
DSCW_47350  citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
DSCW_24870  gltA; citrate synthase [KO:K01647] [EC:2.3.3.1]
DSCW_10830  acoA_2; aconitate hydratase A [KO:K01681] [EC:4.2.1.3]
DSCW_00500  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
DSCW_14350  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
DSCW_16090  hypothetical protein [KO:K00626] [EC:2.3.1.9]
DSCW_16100  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
DSCW_20450  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
DSCW_52450  thil; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
DSCW_52670  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
DSCW_33650  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
DSCW_55510  thlA; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
DSCW_19210  thiolase [KO:K00626] [EC:2.3.1.9]
DSCW_19470  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
DSCW_49490  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
DSCW_55590  hypothetical protein [KO:K00626] [EC:2.3.1.9]
DSCW_55600  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
DSCW_05150  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
DSCW_58190  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
DSCW_64970  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
DSCW_19140  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
DSCW_29800  thiolase [KO:K00626] [EC:2.3.1.9]
DSCW_14480  hypothetical protein [KO:K00626] [EC:2.3.1.9]
DSCW_55620  hypothetical protein [KO:K17865] [EC:4.2.1.55]
DSCW_26670  maoC; dehydratase [KO:K17865] [EC:4.2.1.55]
DSCW_45120  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
DSCW_37210  scpA_2; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
DSCW_45010  glcD_1; FAD-binding protein [KO:K00104] [EC:1.1.99.14]
DSCW_18750  glcD-1; FAD-binding protein [KO:K00104] [EC:1.1.99.14]
DSCW_45000  glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
DSCW_19960  katA; catalase [KO:K03781] [EC:1.11.1.6]
DSCW_07920  hydrolase [KO:K01091] [EC:3.1.3.18]
DSCW_56360  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
DSCW_28810  haloacid dehalogenase [KO:K01091] [EC:3.1.3.18]
DSCW_64540  alanine--glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
DSCW_45190  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
DSCW_55180  glyA_2; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
DSCW_38390  glyA_1; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
DSCW_46080  glycine dehydrogenase [KO:K00282] [EC:1.4.4.2]
DSCW_46070  glycine dehydrogenase [KO:K00283] [EC:1.4.4.2]
DSCW_46100  hypothetical protein [KO:K00605] [EC:2.1.2.10]
DSCW_37840  lpdA-1; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DSCW_43520  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DSCW_46090  gcvH; glycine cleavage system H protein [KO:K02437]
DSCW_29220  garK; glycerate kinase [KO:K00865] [EC:2.7.1.165]
DSCW_61700  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
DSCW_31080  fdnG-3; formate dehydrogenase 2 subunit alpha (cytochrome c-553) [KO:K00123] [EC:1.17.1.9]
DSCW_46380  fdhA; formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
DSCW_46390  formate dehydrogenase subunit beta [KO:K00124]
DSCW_31070  formate dehydrogenase 2 subunit beta (cytochrome c-553) [KO:K00124]
DSCW_42120  hypothetical protein [KO:K00124]
DSCW_33260  hypothetical protein [KO:K00124]
DSCW_55230  hypothetical protein [KO:K00124]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
dwd00010  Glycolysis / Gluconeogenesis
dwd00020  Citrate cycle (TCA cycle)
dwd00030  Pentose phosphate pathway
dwd00053  Ascorbate and aldarate metabolism
dwd00071  Fatty acid degradation
dwd00230  Purine metabolism
dwd00250  Alanine, aspartate and glutamate metabolism
dwd00260  Glycine, serine and threonine metabolism
dwd00620  Pyruvate metabolism
dwd00710  Carbon fixation by Calvin cycle
dwd00750  Vitamin B6 metabolism
dwd00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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