KEGG   PATHWAY: eak00230
Entry
eak00230                    Pathway                                
Name
Purine metabolism - Sinorhizobium alkalisoli
Class
Metabolism; Nucleotide metabolism
Pathway map
eak00230  Purine metabolism
eak00230

Module
eak_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:eak00230]
eak_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:eak00230]
eak_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:eak00230]
eak_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:eak00230]
eak_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:eak00230]
eak_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:eak00230]
Other DBs
GO: 0006163 0042278
Organism
Sinorhizobium alkalisoli [GN:eak]
Gene
EKH55_3384  Phosphopentomutase [KO:K01839] [EC:5.4.2.7]
EKH55_2804  Phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
EKH55_5056  Phosphoglucosamine mutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
EKH55_2317  Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
EKH55_4912  Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
EKH55_0761  Amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
EKH55_0468  Phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
EKH55_0814  Phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
EKH55_1589  Phosphoribosylformylglycinamidine synthase, synthetase subunit [KO:K23269] [EC:6.3.5.3]
EKH55_1573  Phosphoribosylformylglycinamidine synthase, PurS subunit [KO:K23264] [EC:6.3.5.3]
EKH55_1574  Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit [KO:K23265] [EC:6.3.5.3 3.5.1.2]
EKH55_0815  Phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
EKH55_2744  Phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
EKH55_2743  Phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
EKH55_1572  Phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
EKH55_1561  Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
EKH55_3249  IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
EKH55_2361  Adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
EKH55_2763  5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
EKH55_1311  5-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
EKH55_3353  Purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
EKH55_2314  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
EKH55_2610  Hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
EKH55_0376  Inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
EKH55_0798  Nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
EKH55_0006  Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) [KO:K01519] [EC:3.6.1.66]
EKH55_1406  Xanthine-guanine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
EKH55_2417  Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A [KO:K13481] [EC:1.17.1.4]
EKH55_5358  Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A [KO:K13481] [EC:1.17.1.4]
EKH55_2418  Xanthine dehydrogenase, molybdenum binding subunit [KO:K13482] [EC:1.17.1.4]
EKH55_5357  Xanthine dehydrogenase, molybdenum binding subunit [KO:K13482] [EC:1.17.1.4]
EKH55_1618  Xanthine dehydrogenase, molybdenum binding subunit [KO:K11177] [EC:1.17.1.4]
EKH55_4567  Periplasmic aromatic aldehyde oxidoreductase, molybdenum binding subunit YagR [KO:K11177] [EC:1.17.1.4]
EKH55_1617  Periplasmic aromatic aldehyde oxidoreductase, FAD binding subunit YagS [KO:K11178] [EC:1.17.1.4]
EKH55_4568  Periplasmic aromatic aldehyde oxidoreductase, FAD binding subunit YagS [KO:K11178] [EC:1.17.1.4]
EKH55_1615  Periplasmic aromatic aldehyde oxidoreductase, iron-sulfur subunit YagT [KO:K13483]
EKH55_4569  Periplasmic aromatic aldehyde oxidoreductase, iron-sulfur subunit YagT [KO:K13483]
EKH55_3034  Glutamine amidotransferase class-I [KO:K01951] [EC:6.3.5.2]
EKH55_3577  GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
EKH55_2422  Guanine deaminase [KO:K01487] [EC:3.5.4.3]
EKH55_5323  Guanine deaminase [KO:K01487] [EC:3.5.4.3]
EKH55_0782  Guanylate kinase [KO:K00942] [EC:2.7.4.8]
EKH55_1494  Ribonucleotide reductase of class II (coenzyme B12-dependent) [KO:K00525] [EC:1.17.4.1]
EKH55_1298  Deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
EKH55_0739  hypothetical protein [KO:K06952] [EC:3.1.3.89]
EKH55_0707  GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
EKH55_0819  Exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
EKH55_0372  Exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
EKH55_5302  Adenylate cyclase [KO:K01768] [EC:4.6.1.1]
EKH55_2272  Adenylate cyclase [KO:K01768] [EC:4.6.1.1]
EKH55_0093  Adenylate cyclase [KO:K01768] [EC:4.6.1.1]
EKH55_4868  Adenylate cyclase [KO:K01768] [EC:4.6.1.1]
EKH55_4998  Adenylate cyclase [KO:K01768] [EC:4.6.1.1]
EKH55_0820  Adenylate cyclase [KO:K01768] [EC:4.6.1.1]
EKH55_2502  Adenylate cyclase [KO:K01768] [EC:4.6.1.1]
EKH55_1882  Adenylate cyclase [KO:K01768] [EC:4.6.1.1]
EKH55_2727  Adenylate cyclase [KO:K01768] [EC:4.6.1.1]
EKH55_4430  Adenylate cyclase [KO:K01768] [EC:4.6.1.1]
EKH55_2815  Adenylate cyclase [KO:K01768] [EC:4.6.1.1]
EKH55_5392  Adenylate cyclase [KO:K01768] [EC:4.6.1.1]
EKH55_3743  Adenylate cyclase [KO:K01768] [EC:4.6.1.1]
EKH55_5474  Adenylate cyclase [KO:K01768] [EC:4.6.1.1]
EKH55_2839  hypothetical protein [KO:K01768] [EC:4.6.1.1]
EKH55_4565  Adenylate cyclase [KO:K01768] [EC:4.6.1.1]
EKH55_3772  Adenylate cyclase [KO:K01768] [EC:4.6.1.1]
EKH55_3793  Adenylate cyclase [KO:K01768] [EC:4.6.1.1]
EKH55_2678  Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
EKH55_3385  Adenosine deaminase [KO:K01488] [EC:3.5.4.4]
EKH55_0680  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
EKH55_2403  Adenine deaminase [KO:K01486] [EC:3.5.4.2]
EKH55_1416  2',3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
EKH55_2714  Phosphoesterase [KO:K09769] [EC:3.1.4.16]
EKH55_1143  Adenylate kinase [KO:K00939] [EC:2.7.4.3]
EKH55_1242  Nucleoside triphosphate pyrophosphohydrolase MazG [KO:K04765] [EC:3.6.1.9]
EKH55_3705  Ser/Thr protein phosphatase family protein [KO:K03651] [EC:3.1.4.53]
EKH55_0567  Sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
EKH55_0568  Sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
EKH55_2424  Transthyretin family protein [KO:K07127] [EC:3.5.2.17]
EKH55_5359  5-Hydroxyisourate Hydrolase (HIUase) [KO:K07127] [EC:3.5.2.17]
EKH55_2426  Urate oxidase [KO:K13485] [EC:4.1.1.97]
EKH55_5314  Hydantoin racemase [KO:K16841] [EC:5.1.99.3]
EKH55_2427  Uricase (urate oxidase) [KO:K16842] [EC:3.5.2.5]
EKH55_5360  Uricase (urate oxidase) [KO:K16842] [EC:3.5.2.5]
EKH55_3674  Ureidoglycine aminohydrolase [KO:K14977] [EC:3.5.3.26]
EKH55_2425  Ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
EKH55_3668  Ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
EKH55_2523  Urease alpha subunit [KO:K01428] [EC:3.5.1.5]
EKH55_2526  Urease beta subunit [KO:K01429] [EC:3.5.1.5]
EKH55_2527  Urease gamma subunit [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
eak00030  Pentose phosphate pathway
eak00220  Arginine biosynthesis
eak00250  Alanine, aspartate and glutamate metabolism
eak00260  Glycine, serine and threonine metabolism
eak00340  Histidine metabolism
eak00630  Glyoxylate and dicarboxylate metabolism
eak00730  Thiamine metabolism
eak00740  Riboflavin metabolism
eak00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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