KEGG   PATHWAY: ecla00230
Entry
ecla00230                   Pathway                                
Name
Purine metabolism - Enterobacter hormaechei subsp. hoffmannii ECNIH3
Class
Metabolism; Nucleotide metabolism
Pathway map
ecla00230  Purine metabolism
ecla00230

Module
ecla_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:ecla00230]
ecla_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:ecla00230]
ecla_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:ecla00230]
ecla_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:ecla00230]
ecla_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:ecla00230]
Other DBs
GO: 0006163 0042278
Organism
Enterobacter hormaechei subsp. hoffmannii ECNIH3 [GN:ecla]
Gene
ECNIH3_18655  nudF; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
ECNIH3_20405  nudE; adenosine nucleotide hydrolase [KO:K08312] [EC:3.6.1.-]
ECNIH3_03240  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
ECNIH3_06295  phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
ECNIH3_12160  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
ECNIH3_15195  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
ECNIH3_01505  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
ECNIH3_15715  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
ECNIH3_12925  phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
ECNIH3_16030  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
ECNIH3_15710  phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
ECNIH3_05360  phosphoribosylaminoimidazole carboxylase [KO:K01589] [EC:6.3.4.18]
ECNIH3_05365  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
ECNIH3_15630  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
ECNIH3_08440  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
ECNIH3_01510  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
ECNIH3_05225  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
ECNIH3_05275  ushA; 5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
ECNIH3_17000  surE; stationary phase survival protein SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
ECNIH3_06230  UMP phosphatase [KO:K02566] [EC:3.1.3.5]
ECNIH3_20420  nucleotidase [KO:K20881] [EC:3.1.3.-]
ECNIH3_05260  guanosine kinase [KO:K00892] [EC:2.7.1.73]
ECNIH3_03245  deoD; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
ECNIH3_04750  hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
ECNIH3_16270  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
ECNIH3_03845  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
ECNIH3_15790  inosine-5-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
ECNIH3_15855  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
ECNIH3_03300  yjjX; inositol monophosphatase [KO:K01529] [EC:3.6.1.73]
ECNIH3_18085  nucleoside-triphosphate diphosphatase [KO:K01519] [EC:3.6.1.66]
ECNIH3_04400  xanthine-guanine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
ECNIH3_15785  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
ECNIH3_03730  guanosine 5'-monophosphate oxidoreductase [KO:K00364] [EC:1.7.1.7]
ECNIH3_00760  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
ECNIH3_16635  hypothetical protein [KO:K00525] [EC:1.17.4.1]
ECNIH3_14865  ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
ECNIH3_14870  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
ECNIH3_16640  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
ECNIH3_02615  ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
ECNIH3_04015  dgt; deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
ECNIH3_15065  5'-nucleotidase [KO:K08722] [EC:3.1.3.89]
ECNIH3_00750  (p)ppGpp synthetase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
ECNIH3_00970  guanosine polyphosphate pyrophosphohydrolase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
ECNIH3_15725  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
ECNIH3_17125  relA; (p)ppGpp synthetase [KO:K00951] [EC:2.7.6.5]
ECNIH3_01085  cyaA; adenylate cyclase [KO:K05851] [EC:4.6.1.1]
ECNIH3_02290  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
ECNIH3_09520  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
ECNIH3_13895  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
ECNIH3_17195  LOG family protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
ECNIH3_02455  cpdB; 2', 3'-cyclic nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
ECNIH3_05250  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
ECNIH3_17120  mazG; nucleoside triphosphate hydrolase [KO:K04765] [EC:3.6.1.9]
ECNIH3_18645  diguanylate phosphodiesterase [KO:K03651] [EC:3.1.4.53]
ECNIH3_03470  apaH; diadenosine tetraphosphatase [KO:K01525] [EC:3.6.1.41]
ECNIH3_17030  adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
ECNIH3_17035  cysN; sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
ECNIH3_17040  sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
ECNIH3_00620  hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
ECNIH3_18775  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
ECNIH3_22065  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
ECNIH3_18770  ureB; urease subunit beta [KO:K01429] [EC:3.5.1.5]
ECNIH3_18765  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
ECNIH3_22060  hypothetical protein [KO:K14048] [EC:3.5.1.5]
ECNIH3_02685  carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
ecla00030  Pentose phosphate pathway
ecla00220  Arginine biosynthesis
ecla00250  Alanine, aspartate and glutamate metabolism
ecla00260  Glycine, serine and threonine metabolism
ecla00340  Histidine metabolism
ecla00630  Glyoxylate and dicarboxylate metabolism
ecla00730  Thiamine metabolism
ecla00740  Riboflavin metabolism
ecla00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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