KEGG   PATHWAY: ecos00630
Entry
ecos00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Escherichia coli O25b:K100:H4-ST131 EC958 (UPEC)
Class
Metabolism; Carbohydrate metabolism
Pathway map
ecos00630  Glyoxylate and dicarboxylate metabolism
ecos00630

Module
ecos_M00012  Glyoxylate cycle [PATH:ecos00630]
ecos_M00621  Glycine cleavage system [PATH:ecos00630]
Other DBs
GO: 0046487 0043648
Organism
Escherichia coli O25b:K100:H4-ST131 EC958 (UPEC) [GN:ecos]
Gene
EC958_4462  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
EC958_4542  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
EC958_4461  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
EC958_3361  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
EC958_3628  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
EC958_0834  gltA; citrate synthase [KO:K01647] [EC:2.3.3.1]
EC958_0481  prpC; putative citrate synthase [KO:K01659] [EC:2.3.3.5]
EC958_1608  acnA; aconitate hydratase 1 [KO:K27802] [EC:4.2.1.3 4.2.1.99]
EC958_0260  acnB; aconitate hydratase 2 [KO:K01682] [EC:4.2.1.3 4.2.1.99]
EC958_3144  yqeF; probable acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
EC958_2561  atoB; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
EC958_3197  hypothetical protein [KO:K01847] [EC:5.4.99.2]
EC958_3365  glcD; glycolate oxidase subunit D [KO:K00104] [EC:1.1.99.14]
EC958_3364  glycolate oxidase FAD binding subunit [KO:K11472] [EC:1.1.99.14]
EC958_3363  glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
EC958_1953  katE; catalase HPII [KO:K03781] [EC:1.11.1.6]
EC958_1224  ycdW; putative dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
EC958_3959  yiaE; putative dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
EC958_3776  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
EC958_4348  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
EC958_2857  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
EC958_3184  gcvP; decarboxylating glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
EC958_3186  gcvT; aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
EC958_4518  subunit of 2-oxoglutarate dehydrogenase [KO:K00382] [EC:1.8.1.4]
EC958_0258  lpdA; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
EC958_3185  gcvH; Glycine cleavage system H protein [KO:K02437]
EC958_0646  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
EC958_0647  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
EC958_0648  ybbQ; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
EC958_3526  yhaE; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
EC958_3525  yhaD; glycerate kinase 2 [KO:K00865] [EC:2.7.1.165]
EC958_0652  ybbZ; glycerate kinase 1 [KO:K00865] [EC:2.7.1.165]
EC958_1695  aldA; aldehyde dehydrogenase A [KO:K07248] [EC:1.2.1.22 1.2.1.21]
EC958_3069  fucO; lactaldehyde reductase [KO:K00048] [EC:1.1.1.77]
EC958_3467  ttdA; L(+)-tartrate dehydratase alpha subunit [KO:K03779] [EC:4.2.1.32]
EC958_3468  ttdB; L-tartrate dehydratase subunit B [KO:K03780] [EC:4.2.1.32]
EC958_2070  2-keto-3-deoxygluconate 6-phosphate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
EC958_4377  formate dehydrogenase-O, large subunit [KO:K00123] [EC:1.17.1.9]
EC958_4380  formate dehydrogenase-O, large subunit [KO:K00123] [EC:1.17.1.9]
EC958_4376  fdoH; formate dehydrogenase-O, iron-sulfur subunit [KO:K00124]
EC958_4375  fdoI; formate dehydrogenase-O, cytochrome B556 (FDO) subunit [KO:K00127]
EC958_1505  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
EC958_4994  putative oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
EC958_4995  yfdW; Formyl-coenzyme A transferase [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
ecos00010  Glycolysis / Gluconeogenesis
ecos00020  Citrate cycle (TCA cycle)
ecos00030  Pentose phosphate pathway
ecos00053  Ascorbate and aldarate metabolism
ecos00071  Fatty acid degradation
ecos00230  Purine metabolism
ecos00250  Alanine, aspartate and glutamate metabolism
ecos00260  Glycine, serine and threonine metabolism
ecos00620  Pyruvate metabolism
ecos00710  Carbon fixation by Calvin cycle
ecos00750  Vitamin B6 metabolism
ecos00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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