KEGG   PATHWAY: ecs00330
Entry
ecs00330                    Pathway                                
Name
Arginine and proline metabolism - Escherichia coli O157:H7 Sakai (EHEC)
Class
Metabolism; Amino acid metabolism
Pathway map
ecs00330  Arginine and proline metabolism
ecs00330

Module
ecs_M00015  Proline biosynthesis, glutamate => proline [PATH:ecs00330]
ecs_M00133  Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:ecs00330]
ecs_M00136  GABA biosynthesis, prokaryotes, putrescine => GABA [PATH:ecs00330]
ecs_M00879  Arginine succinyltransferase pathway, arginine => glutamate [PATH:ecs00330]
ecs_M00970  Proline degradation, proline => glutamate [PATH:ecs00330]
Other DBs
GO: 0006525 0006560
Organism
Escherichia coli O157:H7 Sakai (EHEC) [GN:ecs]
Gene
ECs_0390  codA; cytosine/isoguanine deaminase [KO:K01485] [EC:3.5.4.1 3.5.4.21]
ECs_5099  adiA; arginine decarboxylase [KO:K01584] [EC:4.1.1.19]
ECs_3814  speA; biosynthetic arginine decarboxylase [KO:K01585] [EC:4.1.1.19]
ECs_3812  speB; agmatinase [KO:K01480] [EC:3.5.3.11]
ECs_0721  speF; ornithine decarboxylase isozyme [KO:K01581] [EC:4.1.1.17]
ECs_3841  speF; ornithine decarboxylase isozyme [KO:K01581] [EC:4.1.1.17]
ECs_0125  speE; spermidine synthase [KO:K00797] [EC:2.5.1.16]
ECs_0124  speD; S-adenosylmethionine decarboxylase [KO:K01611] [EC:4.1.1.50]
ECs_3955  patA; putrescine:2-oxoglutaric acid aminotransferase [KO:K09251] [EC:2.6.1.82]
ECs_2048  patD; gamma-aminobutyraldehyde dehydrogenase [KO:K00137] [EC:1.2.1.19]
ECs_2290  speG; spermidine N(1)-acetyltransferase [KO:K00657] [EC:2.3.1.57]
ECs_2453  astA; arginine succinyltransferase [KO:K00673] [EC:2.3.1.109]
ECs_2451  astB; succinylarginine dihydrolase [KO:K01484] [EC:3.5.3.23]
ECs_2454  astC; succinylornithine transaminase [KO:K00840] [EC:2.6.1.81]
ECs_2452  astD; succinylglutamic semialdehyde dehydrogenase [KO:K06447] [EC:1.2.1.71]
ECs_2450  astE; succinylglutamate desuccinylase [KO:K05526] [EC:3.5.1.96]
ECs_1874  puuA; glutamate--putrescine ligase [KO:K09470] [EC:6.3.1.11]
ECs_1878  puuB; gamma-glutamylputrescine oxidoreductase [KO:K09471] [EC:1.4.3.-]
ECs_1877  puuC; aldehyde dehydrogenase [KO:K09472] [EC:1.2.1.99]
ECs_1875  puuD; gamma-glutamyl-gamma-aminobutyrate hydrolase [KO:K09473] [EC:3.5.1.94]
ECs_0436  proC; pyrroline-5-carboxylate reductase [KO:K00286] [EC:1.5.1.2]
ECs_1260  putA; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase [KO:K13821] [EC:1.5.5.2 1.2.1.88]
ECs_0269  proB; gamma-glutamate kinase [KO:K00931] [EC:2.7.2.11]
ECs_0270  proA; gamma-glutamylphosphate reductase [KO:K00147] [EC:1.2.1.41]
ECs_1011  aspC; aspartate aminotransferase [KO:K00813] [EC:2.6.1.1]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
ecs00020  Citrate cycle (TCA cycle)
ecs00220  Arginine biosynthesis
ecs00250  Alanine, aspartate and glutamate metabolism
ecs00260  Glycine, serine and threonine metabolism
ecs00270  Cysteine and methionine metabolism
ecs00310  Lysine degradation
ecs00410  beta-Alanine metabolism
ecs00470  D-Amino acid metabolism
ecs00480  Glutathione metabolism
ecs00630  Glyoxylate and dicarboxylate metabolism
ecs00650  Butanoate metabolism
ecs00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   
LinkDB

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