KEGG   PATHWAY: efn00230
Entry
efn00230                    Pathway                                
Name
Purine metabolism - Enterococcus faecalis DENG1
Class
Metabolism; Nucleotide metabolism
Pathway map
efn00230  Purine metabolism
efn00230

Module
efn_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:efn00230]
efn_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:efn00230]
efn_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:efn00230]
efn_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:efn00230]
efn_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:efn00230]
Other DBs
GO: 0006163 0042278
Organism
Enterococcus faecalis DENG1 [GN:efn]
Gene
DENG_02637  nudF; MutT/nudix family protein [KO:K01515] [EC:3.6.1.13 3.6.1.-]
DENG_00161  deoB; Phosphopentomutase [KO:K01839] [EC:5.4.2.7]
DENG_02379  pgm; Phosphoglucomutase/phosphomannomutase family protein [KO:K01835] [EC:5.4.2.2]
DENG_02175  prps; Ribose-phosphate pyrophosphokinase 2 [KO:K00948] [EC:2.7.6.1]
DENG_03054  prps; Ribose-phosphate pyrophosphokinase 1 [KO:K00948] [EC:2.7.6.1]
DENG_01964  purF; Amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
DENG_01959  purD; Phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
DENG_01962  purN; Phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
DENG_01965  purL; Phosphoribosylformylglycinamidine synthase 2 [KO:K23269] [EC:6.3.5.3]
DENG_01967  purL; Phosphoribosylformylglycinamidine synthase, PurS protein [KO:K23264] [EC:6.3.5.3]
DENG_01966  purL; Phosphoribosylformylglycinamidine synthase 1 [KO:K23265] [EC:6.3.5.3 3.5.1.2]
DENG_01963  purM; Phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
DENG_01970  purK; Phosphoribosylaminoimidazole carboxylase, ATPase subunit [KO:K01589] [EC:6.3.4.18]
DENG_02309  purK; Phosphoribosylaminoimidazole carboxylase, ATPase subunit [KO:K01589] [EC:6.3.4.18]
DENG_01971  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
DENG_01968  purC; Phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
DENG_02308  purB; Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
DENG_01960  purH; Bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
DENG_01865  apt; Adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
DENG_00162  punA; Purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
DENG_00163  deoD; Purine nucleoside phosphorylase deoD-type [KO:K03784] [EC:2.4.2.1]
DENG_00243  hprT; Hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
DENG_03183  guaB; Inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
DENG_01169  ndk; Nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
DENG_03154  rdgB; Ham1 family protein, putative [KO:K01519] [EC:3.6.1.66]
DENG_02311  xpt; Xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
DENG_00136  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
DENG_02385  guaC; GMP reductase [KO:K00364] [EC:1.7.1.7]
DENG_02388  guaD; Chlorohydrolase family protein [KO:K01487] [EC:3.5.4.3]
DENG_02534  gmk; Guanylate kinase [KO:K00942] [EC:2.7.4.8]
DENG_03014  gmk; Guanylate kinase [KO:K00942] [EC:2.7.4.8]
DENG_00460  nrdA; Ribonucleoside-diphosphate reductase [KO:K00525] [EC:1.17.4.1]
DENG_00459  nrdB; Ribonucleoside-diphosphate reductase 2, beta subunit [KO:K00526] [EC:1.17.4.1]
DENG_02696  nrdD; Anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
DENG_02116  dgt; Deoxyguanosinetriphosphate triphosphohydrolase, putative [KO:K01129] [EC:3.1.5.1]
DENG_02132  relA; GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
DENG_02607  GTP diphosphokinase [KO:K07816] [EC:2.7.6.5]
DENG_00746  Hypothetical protein [KO:K01768] [EC:4.6.1.1]
DENG_00014  purA; Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
DENG_00141  ada; Adenosine deaminase [KO:K01488] [EC:3.5.4.4]
DENG_01367  ade; Adenine deaminase [KO:K01486] [EC:3.5.4.2]
DENG_02802  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase, putative [KO:K01119] [EC:3.1.4.16 3.1.3.6]
DENG_03060  Metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
DENG_00205  adk; Adenylate kinase [KO:K00939] [EC:2.7.4.3]
DENG_02887  allB; Allantoinase [KO:K01466] [EC:3.5.2.5]
DENG_02886  allC; Peptidase, M20/M25/M40 family [KO:K02083] [EC:3.5.3.9]
DENG_02883  Aminotransferase, class V [KO:K00839] [EC:2.6.1.112]
DENG_02885  ylbA; Allantoin catabolism protein [KO:K14977] [EC:3.5.3.26]
DENG_00376  allD; Ureidoglycolate dehydrogenase [KO:K00073] [EC:1.1.1.350]
DENG_00374  arcC; Carbamate kinase 2 [KO:K00926] [EC:2.7.2.2]
DENG_02513  arcC; Carbamate kinase [KO:K00926] [EC:2.7.2.2]
DENG_00109  arcC; Carbamate kinase 1 [KO:K00926] [EC:2.7.2.2]
DENG_00785  arcC; Carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
efn00030  Pentose phosphate pathway
efn00220  Arginine biosynthesis
efn00250  Alanine, aspartate and glutamate metabolism
efn00260  Glycine, serine and threonine metabolism
efn00630  Glyoxylate and dicarboxylate metabolism
efn00730  Thiamine metabolism
efn00740  Riboflavin metabolism
efn00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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