KEGG   PATHWAY: eoi00630
Entry
eoi00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Escherichia coli O111:H- 11128 (EHEC)
Class
Metabolism; Carbohydrate metabolism
Pathway map
eoi00630  Glyoxylate and dicarboxylate metabolism
eoi00630

Module
eoi_M00012  Glyoxylate cycle [PATH:eoi00630]
eoi_M00621  Glycine cleavage system [PATH:eoi00630]
Other DBs
GO: 0046487 0043648
Organism
Escherichia coli O111:H- 11128 (EHEC) [GN:eoi]
Gene
ECO111_4827  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
ECO111_4945  acs; acetyl-CoA synthetase Acs [KO:K01895] [EC:6.2.1.1]
ECO111_3797  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
ECO111_4826  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
ECO111_4056  mdh; malate dehydrogenase, NAD(P)-binding [KO:K00024] [EC:1.1.1.37]
ECO111_0737  gltA; citrate synthase [KO:K01647] [EC:2.3.3.1]
ECO111_1657  acnA; aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
ECO111_0782  ybhJ; predicted hydratase [KO:K01681] [EC:4.2.1.3]
ECO111_0119  acnB; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
ECO111_3573  yqeF; predicted acyltransferase [KO:K00626] [EC:2.3.1.9]
ECO111_3653  yliK; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
ECO111_3801  glcD; glycolate oxidase subunit, FAD-linked [KO:K00104] [EC:1.1.99.14]
ECO111_3800  glcE; glycolate oxidase FAD binding subunit [KO:K11472] [EC:1.1.99.14]
ECO111_3799  glcF; glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
ECO111_2243  katE; hydroperoxidase HPII(III) [KO:K03781] [EC:1.11.1.6]
ECO111_1310  ycdW; 2-ketoacid reductase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
ECO111_4373  tiaE; 2-keto-D-gluconate reductase TiaE [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
ECO111_4194  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
ECO111_4690  glnA; glutamine synthetase GlnA [KO:K01915] [EC:6.3.1.2]
ECO111_3277  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
ECO111_3641  gcvP; glycine decarboxylase, PLP-dependent [KO:K00281] [EC:1.4.4.2]
ECO111_3643  gcvT; aminomethyltransferase, tetrahydrofolate-dependent, subunit of glycine cleavage complex [KO:K00605] [EC:2.1.2.10]
ECO111_0117  lpd; lipoamide dehydrogenase, E3 component [KO:K00382] [EC:1.8.1.4]
ECO111_3642  gcvH; glycine cleavage complex lipoylprotein GcvH [KO:K02437]
ECO111_0540  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
ECO111_0541  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
ECO111_3947  garR; tartronate semialdehyde reductase [KO:K00042] [EC:1.1.1.60]
ECO111_0542  glxR; tartronate semialdehyde reductase, NADH-dependent [KO:K00042] [EC:1.1.1.60]
ECO111_0546  glxK; glycerate kinase II [KO:K00865] [EC:2.7.1.165]
ECO111_3946  garK; glycerate kinase I [KO:K00865] [EC:2.7.1.165]
ECO111_3524  fucO; L-1,2-propanediol oxidoreductase [KO:K00048] [EC:1.1.1.77]
ECO111_3884  ttdA; L-tartrate dehydratase, alpha subunit [KO:K03779] [EC:4.2.1.32]
ECO111_3885  ttdB; L-tartrate dehydratase, beta subunit [KO:K03780] [EC:4.2.1.32]
ECO111_2306  yeaU; predicted dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
ECO111_2358  eda; multifunctional 2-keto-3-deoxygluconate 6-phosphate aldolase and 2-keto-4-hydroxyglutarate aldolase and oxaloacetate decarboxylase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
ECO111_4717  fdoG; formate dehydrogenase-O, major subunit [KO:K00123] [EC:1.17.1.9]
ECO111_4716  fdoH; formate dehydrogenase-O, Fe-S subunit FdoH [KO:K00124]
ECO111_4715  fdoI; formate dehydrogenase-O, cytochrome b556 subunit FdoI [KO:K00127]
ECO111_1560  purU; formyltetrahydrofolate hydrolase [KO:K01433] [EC:3.5.1.10]
ECO111_3109  oxc; predicted oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
ECO111_3110  frc; formyl-CoA transferase Frc, NAD(P)-binding [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
eoi00010  Glycolysis / Gluconeogenesis
eoi00020  Citrate cycle (TCA cycle)
eoi00030  Pentose phosphate pathway
eoi00053  Ascorbate and aldarate metabolism
eoi00071  Fatty acid degradation
eoi00230  Purine metabolism
eoi00250  Alanine, aspartate and glutamate metabolism
eoi00260  Glycine, serine and threonine metabolism
eoi00620  Pyruvate metabolism
eoi00710  Carbon fixation by Calvin cycle
eoi00750  Vitamin B6 metabolism
eoi00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

DBGET integrated database retrieval system