KEGG   PATHWAY: hbr00600
Entry
hbr00600                    Pathway                                
Name
Sphingolipid metabolism - Hevea brasiliensis (rubber tree)
Class
Metabolism; Lipid metabolism
Pathway map
hbr00600  Sphingolipid metabolism
hbr00600

Module
hbr_M00100  Sphingosine degradation [PATH:hbr00600]
Other DBs
GO: 0006665
Organism
Hevea brasiliensis (rubber tree) [GN:hbr]
Gene
110668293  long chain base biosynthesis protein 1 isoform X1 [KO:K00654] [EC:2.3.1.50]
110671852  long chain base biosynthesis protein 2a-like isoform X1 [KO:K00654] [EC:2.3.1.50]
110637702  long chain base biosynthesis protein 2a isoform X1 [KO:K00654] [EC:2.3.1.50]
110636656  long chain base biosynthesis protein 2a-like isoform X1 [KO:K00654] [EC:2.3.1.50]
110666330  neutral ceramidase 1-like [KO:K12349] [EC:3.5.1.23]
110661014  neutral ceramidase 2-like [KO:K12349] [EC:3.5.1.23]
110648977  neutral ceramidase 2-like [KO:K12349] [EC:3.5.1.23]
110640648  neutral ceramidase 1-like isoform X1 [KO:K12349] [EC:3.5.1.23]
110640649  neutral ceramidase 1-like [KO:K12349] [EC:3.5.1.23]
110648549  alkaline ceramidase-like [KO:K04711] [EC:3.5.1.-]
110636221  alkaline ceramidase-like [KO:K04711] [EC:3.5.1.-]
110649157  sphingolipid delta(4)-desaturase DES1-like [KO:K04712] [EC:1.14.19.17 1.14.18.5]
110635114  sphingolipid delta(4)-desaturase DES1-like [KO:K04712] [EC:1.14.19.17 1.14.18.5]
110645469  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
110635189  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
110638775  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
110640540  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
110669606  ceramide kinase [KO:K04715] [EC:2.7.1.138]
110664617  sphingosine kinase 1-like isoform X1 [KO:K04718] [EC:2.7.1.91]
110638162  sphingosine-1-phosphate lyase isoform X1 [KO:K01634] [EC:4.1.2.27]
110669883  non-lysosomal glucosylceramidase-like [KO:K17108] [EC:3.2.1.45]
110672296  non-lysosomal glucosylceramidase-like [KO:K17108] [EC:3.2.1.45]
110672298  non-lysosomal glucosylceramidase-like isoform X1 [KO:K17108] [EC:3.2.1.45]
110651732  non-lysosomal glucosylceramidase-like [KO:K17108] [EC:3.2.1.45]
110650687  non-lysosomal glucosylceramidase-like isoform X1 [KO:K17108] [EC:3.2.1.45]
110668997  non-lysosomal glucosylceramidase-like isoform X1 [KO:K17108] [EC:3.2.1.45]
110641341  non-lysosomal glucosylceramidase-like [KO:K17108] [EC:3.2.1.45]
110667408  uncharacterized protein LOC110667408 [KO:K01190] [EC:3.2.1.23]
110668067  beta-galactosidase 17-like isoform X1 [KO:K12309] [EC:3.2.1.23]
110668073  beta-galactosidase 17-like isoform X1 [KO:K12309] [EC:3.2.1.23]
110669696  alpha-galactosidase 3-like [KO:K07407] [EC:3.2.1.22]
110654552  alpha-galactosidase-like [KO:K07407] [EC:3.2.1.22]
110661560  alpha-galactosidase 1-like isoform X1 [KO:K07407] [EC:3.2.1.22]
110666614  alpha-galactosidase 1-like [KO:K07407] [EC:3.2.1.22]
110648108  alpha-galactosidase-like [KO:K07407] [EC:3.2.1.22]
110668068  alpha-galactosidase 3-like isoform X1 [KO:K07407] [EC:3.2.1.22]
110669332  beta-hexosaminidase 2 [KO:K12373] [EC:3.2.1.52]
110650198  beta-hexosaminidase 1 isoform X1 [KO:K12373] [EC:3.2.1.52]
110640126  beta-hexosaminidase 3 [KO:K12373] [EC:3.2.1.52]
110657015  prosaposin [KO:K12382]
110638239  prosaposin-like isoform X1 [KO:K12382]
Compound
C00065  L-Serine
C00154  Palmitoyl-CoA
C00195  N-Acylsphingosine
C00319  Sphingosine
C00346  Ethanolamine phosphate
C00550  Sphingomyelin
C00836  Sphinganine
C01120  Sphinganine 1-phosphate
C01190  Glucosylceramide
C01290  Lactosylceramide
C01747  Psychosine
C02686  Galactosylceramide
C02934  3-Dehydrosphinganine
C02960  Ceramide 1-phosphate
C03108  D-Glucosylsphingosine
C03272  Globoside
C03405  Lactosylceramide sulfate
C03640  Sphingosyl-phosphocholine
C04730  GM3
C04737  alpha-D-Galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide
C04884  N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide
C04911  D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide
C05681  Ceramide 2-aminoethylphosphonate
C06062  Ceramide phosphoethanolamine
C06124  Sphingosine 1-phosphate
C06125  Sulfatide
C06126  Digalactosylceramide
C06127  Digalactosylceramide sulfate
C06128  GM4
C06135  GA2
C06136  GA1
C12126  Dihydroceramide
C12144  Phytosphingosine
C12145  Phytoceramide
C22467  Gangliotriaosylceramide-II3 sulfate
Reference
PMID:12011104
  Authors
Merrill AH Jr.
  Title
De novo sphingolipid biosynthesis: a necessary, but dangerous, pathway.
  Journal
J Biol Chem 277:25843-6 (2002)
DOI:10.1074/jbc.R200009200
Reference
PMID:10652340
  Authors
Tani M, Okino N, Mitsutake S, Tanigawa T, Izu H, Ito M.
  Title
Purification and characterization of a neutral ceramidase from mouse liver. A single protein catalyzes the reversible reaction in which ceramide is both hydrolyzed and synthesized.
  Journal
J Biol Chem 275:3462-8 (2000)
DOI:10.1074/jbc.275.5.3462
Reference
PMID:11305904
  Authors
Hannun YA, Luberto C, Argraves KM.
  Title
Enzymes of sphingolipid metabolism: from modular to integrative signaling.
  Journal
Biochemistry 40:4893-903 (2001)
DOI:10.1021/bi002836k
Reference
PMID:1495423
  Authors
Merrill AH Jr, Wang E.
  Title
Enzymes of ceramide biosynthesis.
  Journal
Methods Enzymol 209:427-37 (1992)
DOI:10.1016/0076-6879(92)09053-6
Reference
PMID:8457204
  Authors
Hirschberg K, Rodger J, Futerman AH.
  Title
The long-chain sphingoid base of sphingolipids is acylated at the cytosolic surface of the endoplasmic reticulum in rat liver.
  Journal
Biochem J 290 ( Pt 3):751-7 (1993)
DOI:10.1042/bj2900751
Reference
PMID:10366774
  Authors
Dickson RC, Lester RL.
  Title
Metabolism and selected functions of sphingolipids in the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1438:305-21 (1999)
DOI:10.1016/S1388-1981(99)00068-2
Related
pathway
hbr00260  Glycine, serine and threonine metabolism
hbr00601  Glycosphingolipid biosynthesis - lacto and neolacto series
hbr00603  Glycosphingolipid biosynthesis - globo and isoglobo series
hbr00604  Glycosphingolipid biosynthesis - ganglio series
KO pathway
ko00600   
LinkDB

DBGET integrated database retrieval system