KEGG   PATHWAY: hjt00630
Entry
hjt00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Natrinema thermotolerans
Class
Metabolism; Carbohydrate metabolism
Pathway map
hjt00630  Glyoxylate and dicarboxylate metabolism
hjt00630

Module
hjt_M00621  Glycine cleavage system [PATH:hjt00630]
hjt_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:hjt00630]
hjt_M00968  Pentose bisphosphate pathway (nucleoside degradation), archaea, nucleoside/NMP => 3-PGA/glycerone phosphate [PATH:hjt00630]
Other DBs
GO: 0046487 0043648
Organism
Natrinema thermotolerans [GN:hjt]
Gene
DVR14_04730  acyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
DVR14_10905  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
DVR14_24225  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
DVR14_05490  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
DVR14_03370  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DVR14_03380  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DVR14_09205  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
DVR14_18730  lactate dehydrogenase [KO:K00024] [EC:1.1.1.37]
DVR14_12995  citrate synthase [KO:K01659] [EC:2.3.3.5]
DVR14_02400  acnA; aconitate hydratase AcnA [KO:K27802] [EC:4.2.1.3 4.2.1.99]
DVR14_23255  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
DVR14_19125  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
DVR14_02570  thiolase family protein [KO:K00626] [EC:2.3.1.9]
DVR14_24845  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
DVR14_04335  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
DVR14_15280  acyl dehydratase [KO:K17865] [EC:4.2.1.55]
DVR14_03545  dehydratase [KO:K17865] [EC:4.2.1.55]
DVR14_22740  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
DVR14_18605  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
DVR14_02940  MaoC family dehydratase [KO:K14449] [EC:4.2.1.148]
DVR14_02665  acetyl-CoA carboxylase biotin carboxylase subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
DVR14_04740  acetyl-CoA carboxylase biotin carboxylase subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
DVR14_02685  acyl-CoA carboxylase subunit beta [KO:K19312] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
DVR14_02680  hypothetical protein [KO:K22568] [EC:6.4.1.2 6.4.1.3]
DVR14_24865  methylmalonyl-CoA mutase [KO:K01849] [EC:5.4.99.2]
DVR14_04310  methylmalonyl-CoA mutase [KO:K01849] [EC:5.4.99.2]
DVR14_24860  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
DVR14_18610  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
DVR14_02950  methylaspartate mutase subunit E [KO:K19268] [EC:5.4.99.1]
DVR14_02955  methylaspartate mutase subunit S [KO:K01846] [EC:5.4.99.1]
DVR14_13275  methylaspartate mutase subunit S [KO:K01846] [EC:5.4.99.1]
DVR14_02945  methylaspartate ammonia-lyase [KO:K04835] [EC:4.3.1.2]
DVR14_02960  CoA transferase [KO:K19280] [EC:2.8.3.26]
DVR14_02935  citrate lyase subunit beta [KO:K19281] [EC:4.1.3.24]
DVR14_12080  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
DVR14_18655  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
DVR14_22790  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
DVR14_14375  HAD-IIB family hydrolase [KO:K22223] [EC:3.1.3.18]
DVR14_19385  alanine--glyoxylate aminotransferase family protein [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
DVR14_11645  glutamate synthase large subunit [KO:K00284] [EC:1.4.7.1]
DVR14_14865  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
DVR14_11415  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
DVR14_02505  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
DVR14_17435  aminomethyl-transferring glycine dehydrogenase subunit GcvPA [KO:K00282] [EC:1.4.4.2]
DVR14_21565  aminomethyl-transferring glycine dehydrogenase subunit GcvPA [KO:K00282] [EC:1.4.4.2]
DVR14_17440  glycine dehydrogenase subunit 2 [KO:K00283] [EC:1.4.4.2]
DVR14_21570  glycine dehydrogenase subunit 2 [KO:K00283] [EC:1.4.4.2]
DVR14_11440  aminomethyl transferase family protein [KO:K00605] [EC:2.1.2.10]
DVR14_21500  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
DVR14_17370  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
DVR14_10530  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DVR14_21495  gcvH; glycine cleavage system protein GcvH [KO:K02437]
DVR14_17365  gcvH; glycine cleavage system protein GcvH [KO:K02437]
DVR14_06180  DUF4147 domain-containing protein [KO:K11529] [EC:2.7.1.165]
DVR14_13240  HAD family hydrolase [KO:K26210] [EC:3.1.3.109]
DVR14_13235  class II aldolase/adducin family protein [KO:K01636] [EC:4.1.2.-]
DVR14_05820  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
DVR14_05815  acetamidase/formamidase family protein [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
hjt00010  Glycolysis / Gluconeogenesis
hjt00020  Citrate cycle (TCA cycle)
hjt00030  Pentose phosphate pathway
hjt00053  Ascorbate and aldarate metabolism
hjt00071  Fatty acid degradation
hjt00230  Purine metabolism
hjt00250  Alanine, aspartate and glutamate metabolism
hjt00260  Glycine, serine and threonine metabolism
hjt00620  Pyruvate metabolism
hjt00710  Carbon fixation by Calvin cycle
hjt00750  Vitamin B6 metabolism
hjt00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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