KEGG   PATHWAY: mfg00630
Entry
mfg00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycolicibacterium farcinogenes
Class
Metabolism; Carbohydrate metabolism
Pathway map
mfg00630  Glyoxylate and dicarboxylate metabolism
mfg00630

Module
mfg_M00012  Glyoxylate cycle [PATH:mfg00630]
mfg_M00621  Glycine cleavage system [PATH:mfg00630]
mfg_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mfg00630]
Other DBs
GO: 0046487 0043648
Organism
Mycolicibacterium farcinogenes [GN:mfg]
Gene
K6L26_27050  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
K6L26_15080  aceA; isocitrate lyase ICL2 [KO:K01637] [EC:4.1.3.1 4.1.3.30]
K6L26_04540  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
K6L26_07015  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
K6L26_15345  malate synthase G [KO:K01638] [EC:2.3.3.9]
K6L26_23415  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
K6L26_06900  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
K6L26_06920  citrate synthase [KO:K01647] [EC:2.3.3.1]
K6L26_11720  bifunctional 2-methylcitrate synthase/citrate synthase [KO:K01659] [EC:2.3.3.5]
K6L26_17760  aconitate hydratase [KO:K27802] [EC:4.2.1.3 4.2.1.99]
K6L26_21675  thiolase family protein [KO:K00626] [EC:2.3.1.9]
K6L26_21750  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
K6L26_22915  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
K6L26_29900  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
K6L26_05520  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
K6L26_05605  steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
K6L26_05805  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
K6L26_06675  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
K6L26_07695  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
K6L26_08800  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
K6L26_10525  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
K6L26_13765  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
K6L26_15500  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
K6L26_10520  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
K6L26_23405  acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
K6L26_23360  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
K6L26_23365  acyl-CoA carboxylase subunit epsilon [KO:K27095]
K6L26_13120  acyl-CoA carboxylase subunit beta [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
K6L26_17685  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
K6L26_17690  mutA; methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
K6L26_10785  cobalamin B12-binding domain-containing protein [KO:K01849] [EC:5.4.99.2]
K6L26_10780  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
K6L26_30075  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
K6L26_09915  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
K6L26_24465  catalase [KO:K03781] [EC:1.11.1.6]
K6L26_18170  catalase family peroxidase [KO:K03781] [EC:1.11.1.6]
K6L26_13205  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
K6L26_24775  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
K6L26_29420  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
K6L26_03845  glnT; type III glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
K6L26_13295  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
K6L26_13325  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
K6L26_15665  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
K6L26_19995  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
K6L26_08935  glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
K6L26_15335  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
K6L26_13385  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
K6L26_27075  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
K6L26_15310  gcvH; glycine cleavage system protein GcvH [KO:K02437]
K6L26_20275  glycerate kinase [KO:K00865] [EC:2.7.1.165]
K6L26_29160  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
K6L26_09840  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
K6L26_21790  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
K6L26_12870  acetamidase/formamidase family protein [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mfg00010  Glycolysis / Gluconeogenesis
mfg00020  Citrate cycle (TCA cycle)
mfg00030  Pentose phosphate pathway
mfg00053  Ascorbate and aldarate metabolism
mfg00071  Fatty acid degradation
mfg00230  Purine metabolism
mfg00250  Alanine, aspartate and glutamate metabolism
mfg00260  Glycine, serine and threonine metabolism
mfg00620  Pyruvate metabolism
mfg00710  Carbon fixation by Calvin cycle
mfg00750  Vitamin B6 metabolism
mfg00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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