KEGG   PATHWAY: mia00630
Entry
mia00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycobacterium intracellulare ATCC 13950
Class
Metabolism; Carbohydrate metabolism
Pathway map
mia00630  Glyoxylate and dicarboxylate metabolism
mia00630

Module
mia_M00012  Glyoxylate cycle [PATH:mia00630]
mia_M00621  Glycine cleavage system [PATH:mia00630]
mia_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mia00630]
Other DBs
GO: 0046487 0043648
Organism
Mycobacterium intracellulare ATCC 13950 [GN:mia]
Gene
OCU_26010  isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
OCU_45490  isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
OCU_04130  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
OCU_26980  malate synthase G [KO:K01638] [EC:2.3.3.9]
OCU_12850  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
OCU_08920  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
OCU_08960  type II citrate synthase [KO:K01647] [EC:2.3.3.1]
OCU_03040  citrate synthase [KO:K01659] [EC:2.3.3.5]
OCU_31440  aconitate hydratase [KO:K27802] [EC:4.2.1.3 4.2.1.99]
OCU_26670  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
OCU_05170  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
OCU_05290  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
OCU_05500  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
OCU_09470  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
OCU_13840  thiolase [KO:K00626] [EC:2.3.1.9]
OCU_11020  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
OCU_09120  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
OCU_37750  beta-ketoadipyl CoA thiolase [KO:K00626] [EC:2.3.1.9]
OCU_48210  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
OCU_08530  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
OCU_16270  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
OCU_16550  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
OCU_14000  lipid-transfer protein [KO:K00626] [EC:2.3.1.9]
OCU_16820  putative thiolase [KO:K00626] [EC:2.3.1.9]
OCU_28230  nonspecific lipid-transfer protein [KO:K00626] [EC:2.3.1.9]
OCU_16260  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
OCU_41130  accA3 [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
OCU_41080  propionyl-CoA carboxylase beta chain [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
OCU_41090  hypothetical protein [KO:K27095]
OCU_21950  propionyl-CoA carboxylase beta chain [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
OCU_31170  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
OCU_31180  methylmalonyl-CoA mutase, small subunit [KO:K01847] [EC:5.4.99.2]
OCU_07090  putative methylmalonyl-CoA mutase [KO:K01849] [EC:5.4.99.2]
OCU_07080  methylmalonyl-CoA mutase protein [KO:K01848] [EC:5.4.99.2]
OCU_15530  oxidoreductase, FAD-binding protein [KO:K00104] [EC:1.1.99.14]
OCU_21570  putative dehydrogenase [KO:K00104] [EC:1.1.99.14]
OCU_33500  catalase [KO:K03781] [EC:1.11.1.6]
OCU_39110  catalase HPII [KO:K03781] [EC:1.11.1.6]
OCU_22120  hypothetical protein [KO:K01091] [EC:3.1.3.18]
OCU_26450  glutamine synthetase catalytic domain protein [KO:K01915] [EC:6.3.1.2]
OCU_35520  glutamine synthetase catalytic domain protein [KO:K01915] [EC:6.3.1.2]
OCU_22300  glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
OCU_22370  glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
OCU_11190  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
OCU_27030  glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
OCU_22490  glycine cleavage system aminomethyltransferase T [KO:K00605] [EC:2.1.2.10]
OCU_45540  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
OCU_27080  glycine cleavage system protein H [KO:K02437]
OCU_22550  hypothetical protein [KO:K00865] [EC:2.7.1.165]
OCU_12900  alpha-ketoglutarate decarboxylase [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
OCU_48350  formate dehydrogenase [KO:K00122] [EC:1.17.1.9]
OCU_50140  putative oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mia00010  Glycolysis / Gluconeogenesis
mia00020  Citrate cycle (TCA cycle)
mia00030  Pentose phosphate pathway
mia00053  Ascorbate and aldarate metabolism
mia00071  Fatty acid degradation
mia00230  Purine metabolism
mia00250  Alanine, aspartate and glutamate metabolism
mia00260  Glycine, serine and threonine metabolism
mia00620  Pyruvate metabolism
mia00710  Carbon fixation by Calvin cycle
mia00750  Vitamin B6 metabolism
mia00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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