KEGG   PATHWAY: mno00630
Entry
mno00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Methylobacterium nodulans
Class
Metabolism; Carbohydrate metabolism
Pathway map
mno00630  Glyoxylate and dicarboxylate metabolism
mno00630

Module
mno_M00621  Glycine cleavage system [PATH:mno00630]
mno_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mno00630]
Other DBs
GO: 0046487 0043648
Organism
Methylobacterium nodulans [GN:mno]
Gene
Mnod_1158  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
Mnod_3983  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
Mnod_4783  acetate/CoA ligase [KO:K01895] [EC:6.2.1.1]
Mnod_5208  acetate/CoA ligase [KO:K01895] [EC:6.2.1.1]
Mnod_0188  malate synthase G [KO:K01638] [EC:2.3.3.9]
Mnod_1123  malate dehydrogenase, NAD-dependent [KO:K00024] [EC:1.1.1.37]
Mnod_1524  citrate synthase I [KO:K01647] [EC:2.3.3.1]
Mnod_0174  aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
Mnod_2774  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
Mnod_7117  succinyl-CoA synthetase, alpha subunit [KO:K08692] [EC:6.2.1.9]
Mnod_7116  succinyl-CoA synthetase, beta subunit [KO:K14067] [EC:6.2.1.9]
Mnod_6744  Thiolase [KO:K00626] [EC:2.3.1.9]
Mnod_3980  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mnod_4781  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mnod_7471  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mnod_5240  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mnod_3077  Thiolase [KO:K00626] [EC:2.3.1.9]
Mnod_5443  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mnod_5917  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mnod_4780  acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
Mnod_5916  acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
Mnod_5970  MaoC domain protein dehydratase [KO:K17865] [EC:4.2.1.55]
Mnod_7894  MaoC domain protein dehydratase [KO:K17865] [EC:4.2.1.55]
Mnod_0039  crotonyl-CoA reductase [KO:K14446] [EC:1.3.1.85]
Mnod_4142  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
Mnod_0038  methylmalonyl-CoA mutase, large subunit [KO:K14447] [EC:5.4.99.63]
Mnod_4511  acyl-CoA dehydrogenase domain protein [KO:K14448] [EC:1.3.8.12]
Mnod_3627  MaoC domain protein dehydratase [KO:K14449] [EC:4.2.1.148]
Mnod_7119  HpcH/HpaI aldolase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
Mnod_7178  HpcH/HpaI aldolase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
Mnod_1878  Carbamoyl-phosphate synthase L chain ATP-binding [KO:K01965] [EC:6.4.1.3]
Mnod_5510  carboxyl transferase [KO:K01966] [EC:6.4.1.3 2.1.3.15]
Mnod_5425  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
Mnod_4573  methylmalonyl-CoA mutase, large subunit [KO:K01847] [EC:5.4.99.2]
Mnod_4582  FAD linked oxidase domain protein [KO:K00104] [EC:1.1.99.14]
Mnod_0677  FAD linked oxidase domain protein [KO:K11472] [EC:1.1.99.14]
Mnod_0680  protein of unknown function DUF224 cysteine-rich region domain protein [KO:K11473] [EC:1.1.99.14]
Mnod_5249  Catalase domain protein [KO:K03781] [EC:1.11.1.6]
Mnod_6547  Catalase domain protein [KO:K03781] [EC:1.11.1.6]
Mnod_0378  D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [KO:K00015] [EC:1.1.1.26]
Mnod_1511  D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [KO:K12972] [EC:1.1.1.79 1.1.1.81]
Mnod_2906  D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [KO:K12972] [EC:1.1.1.79 1.1.1.81]
Mnod_7113  D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [KO:K00018] [EC:1.1.1.29]
Mnod_6944  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
Mnod_1296  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
Mnod_7122  HAD-superfamily hydrolase, subfamily IA, variant 1 [KO:K01091] [EC:3.1.3.18]
Mnod_6360  Haloacid dehalogenase domain protein hydrolase [KO:K01091] [EC:3.1.3.18]
Mnod_2767  aminotransferase class V [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
Mnod_4911  aminotransferase class V [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
Mnod_7112  aminotransferase class V [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
Mnod_3383  glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
Mnod_4507  glutamine synthetase catalytic region [KO:K01915] [EC:6.3.1.2]
Mnod_8463  glutamine synthetase catalytic region [KO:K01915] [EC:6.3.1.2]
Mnod_7410  glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
Mnod_8588  glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Mnod_3404  glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Mnod_5297  glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Mnod_5869  glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Mnod_6033  glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
Mnod_6035  glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
Mnod_6519  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Mnod_1130  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Mnod_7193  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Mnod_6034  glycine cleavage system H protein [KO:K02437]
Mnod_3087  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
Mnod_3088  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
Mnod_7094  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
Mnod_3089  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
Mnod_8654  6-phosphogluconate dehydrogenase NAD-binding [KO:K00042] [EC:1.1.1.60]
Mnod_6898  6-phosphogluconate dehydrogenase NAD-binding [KO:K00042] [EC:1.1.1.60]
Mnod_0654  MOFRL domain protein [KO:K11529] [EC:2.7.1.165]
Mnod_5964  MOFRL domain protein [KO:K11529] [EC:2.7.1.165]
Mnod_8669  hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit [KO:K03779] [EC:4.2.1.32]
Mnod_8668  Fe-S type hydro-lyase tartrate/fumarate beta region [KO:K03780] [EC:4.2.1.32]
Mnod_1445  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
Mnod_5811  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
Mnod_4545  2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
Mnod_0253  conserved hypothetical protein [KO:K00126] [EC:1.17.1.9]
Mnod_0255  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
Mnod_5226  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
Mnod_5278  molybdopterin oxidoreductase [KO:K00123] [EC:1.17.1.9]
Mnod_8358  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
Mnod_8359  Respiratory-chain NADH dehydrogenase domain 51 kDa subunit [KO:K22515] [EC:1.17.1.9]
Mnod_5227  Respiratory-chain NADH dehydrogenase domain 51 kDa subunit [KO:K22515] [EC:1.17.1.9]
Mnod_5279  4Fe-4S ferredoxin iron-sulfur binding domain protein [KO:K00124]
Mnod_0256  Respiratory-chain NADH dehydrogenase domain 51 kDa subunit [KO:K00124]
Mnod_0257  NADH dehydrogenase (ubiquinone) 24 kDa subunit [KO:K00127]
Mnod_5280  formate dehydrogenase, gamma subunit [KO:K00127]
Mnod_1199  putative esterase/lipase [KO:K01432] [EC:3.5.1.9]
Mnod_1738  conserved hypothetical protein [KO:K01432] [EC:3.5.1.9]
Mnod_1037  N-formylglutamate amidohydrolase [KO:K01458] [EC:3.5.1.68]
Mnod_0049  AMP-dependent synthetase and ligase [KO:K22133] [EC:6.2.1.8]
Mnod_4838  oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
Mnod_4823  formyl-CoA transferase [KO:K07749] [EC:2.8.3.16]
Mnod_8713  formyl-CoA transferase [KO:K07749] [EC:2.8.3.16]
Mnod_4840  formyl-CoA transferase [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mno00010  Glycolysis / Gluconeogenesis
mno00020  Citrate cycle (TCA cycle)
mno00030  Pentose phosphate pathway
mno00053  Ascorbate and aldarate metabolism
mno00071  Fatty acid degradation
mno00230  Purine metabolism
mno00250  Alanine, aspartate and glutamate metabolism
mno00260  Glycine, serine and threonine metabolism
mno00620  Pyruvate metabolism
mno00710  Carbon fixation by Calvin cycle
mno00750  Vitamin B6 metabolism
mno00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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