KEGG   PATHWAY: mor00230
Entry
mor00230                    Pathway                                
Name
Purine metabolism - Methylobacterium oryzae
Class
Metabolism; Nucleotide metabolism
Pathway map
mor00230  Purine metabolism
mor00230

Module
mor_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:mor00230]
mor_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:mor00230]
mor_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:mor00230]
mor_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:mor00230]
mor_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:mor00230]
mor_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:mor00230]
Other DBs
GO: 0006163 0042278
Organism
Methylobacterium oryzae [GN:mor]
Gene
MOC_1028  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
MOC_2141  Phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
MOC_1863  Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
MOC_4445  purF; Amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
MOC_1900  Phosphoribosylamine-glycine ligase [KO:K01945] [EC:6.3.4.13]
MOC_0647  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
MOC_1349  purL; Phosphoribosylformylglycinamidine synthase, synthetase subunit [KO:K23269] [EC:6.3.5.3]
MOC_5029  purS; Phosphoribosylformylglycinamidine synthase, PurS subunit [KO:K23264] [EC:6.3.5.3]
MOC_5028  purQ; Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit [KO:K23265] [EC:6.3.5.3 3.5.1.2]
MOC_0648  Phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
MOC_1283  Phosphoribosylaminoimidazole carboxylase, ATPase subunit [KO:K01589] [EC:6.3.4.18]
MOC_1284  Phosphoribosylaminoimidazole carboxylase, catalytic subunit [KO:K01588] [EC:5.4.99.18]
MOC_3318  Phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
MOC_4001  purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
MOC_6219  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
MOC_6175  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
MOC_4019  apt; Adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
MOC_2700  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
MOC_4480  Purine nucleotide phosphorylase [KO:K03783] [EC:2.4.2.1]
MOC_5984  protein of unassigned function [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
MOC_4570  hpt; Hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
MOC_0085  guaB; Inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
MOC_0645  Nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
MOC_3309  rdgB; rdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
MOC_6037  Aldehyde oxidase/xanthine dehydrogenase molybdopterin binding subunit [KO:K11177] [EC:1.17.1.4]
MOC_4916  Aldehyde oxidase/xanthine dehydrogenase molybdopterin binding subunit [KO:K11177] [EC:1.17.1.4]
MOC_1716  Aldehyde oxidase/xanthine dehydrogenase molybdopterin binding subunit [KO:K11177] [EC:1.17.1.4]
MOC_5145  Aldehyde oxidase/xanthine dehydrogenase molybdopterin binding subunit [KO:K11177] [EC:1.17.1.4]
MOC_1906  Aldehyde oxidase/xanthine dehydrogenase molybdopterin binding subunit [KO:K11177] [EC:1.17.1.4]
MOC_6038  Molybdopterin dehydrogenase FAD-binding protein [KO:K11178] [EC:1.17.1.4]
MOC_4915  Molybdopterin dehydrogenase FAD-binding protein [KO:K11178] [EC:1.17.1.4]
MOC_5144  Molybdopterin dehydrogenase FAD-binding protein [KO:K11178] [EC:1.17.1.4]
MOC_1907  Molybdopterin dehydrogenase FAD-binding protein [KO:K11178] [EC:1.17.1.4]
MOC_6039  2Fe-2S iron-sulfur cluster binding domain-containing protein [KO:K13483]
MOC_4914  Xanthine dehydrogenase iron-sulfur cluster binding subunit [KO:K13483]
MOC_5143  2Fe-2S iron-sulfur cluster binding domain-containing protein [KO:K13483]
MOC_1908  2Fe-2S iron-sulfur cluster binding domain-containing protein [KO:K13483]
MOC_5735  Glutamine amidotransferase class-I [KO:K01951] [EC:6.3.5.2]
MOC_0607  GMP synthetase large subunit [KO:K01951] [EC:6.3.5.2]
MOC_6013  CMP/dCMP deaminase zinc-binding protein [KO:K01487] [EC:3.5.4.3]
MOC_5510  CMP/dCMP deaminase zinc-binding protein [KO:K01487] [EC:3.5.4.3]
MOC_4245  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
MOC_0308  Adenosylcobalamin-dependent ribonucleoside-diphosphate reductase [KO:K00525] [EC:1.17.4.1]
MOC_3134  Deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
MOC_4558  Metal-dependent phosphohydrolase [KO:K06952] [EC:3.1.3.89]
MOC_2300  (P)ppGpp synthetase I, SpoT/RelA [KO:K01139] [EC:2.7.6.5 3.1.7.2]
MOC_0146  Ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
MOC_0652  Ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
MOC_6238  Adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
MOC_5086  Adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
MOC_1203  Adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
MOC_4872  Adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
MOC_3558  Adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
MOC_3665  Putative adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
MOC_1730  Adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
MOC_0472  Adenylate/guanylate cyclase with Chase sensor [KO:K01768] [EC:4.6.1.1]
MOC_0736  Adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
MOC_0995  Putative adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
MOC_1873  Adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
MOC_4910  Adenylate cyclase [KO:K01768] [EC:4.6.1.1]
MOC_0227  Adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
MOC_6222  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
MOC_0610  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
MOC_3214  ade; adenine deaminase [KO:K01486] [EC:3.5.4.2]
MOC_5932  Metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
MOC_2610  Adenylate kinase [KO:K00939] [EC:2.7.4.3]
MOC_2024  mazG; Nucleoside triphosphate pyrophosphohydrolase MazG [KO:K04765] [EC:3.6.1.9]
MOC_4876  Metallophosphoesterase [KO:K03651] [EC:3.1.4.53]
MOC_2287  Adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
MOC_2188  Sulfate adenylyltransferase, large subunit [KO:K00956] [EC:2.7.7.4]
MOC_2187  Sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
MOC_0208  pucL; urate oxidase [KO:K00365] [EC:1.7.3.3]
MOC_1477  Putative transthyretin-like protein [KO:K07127] [EC:3.5.2.17]
MOC_3824  uraH; Hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
MOC_5333  OHCU decarboxylase [KO:K13485] [EC:4.1.1.97]
MOC_5848  Asp/Glu/hydantoin racemase [KO:K16841] [EC:5.1.99.3]
MOC_1475  Asp/Glu/hydantoin racemase [KO:K16841] [EC:5.1.99.3]
MOC_3377  protein of unassigned function [KO:K14977] [EC:3.5.3.26]
MOC_3376  Ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
MOC_3229  ureC; Urease, alpha subunit [KO:K01428] [EC:3.5.1.5]
MOC_3228  Urease beta/gamma subunit [KO:K14048] [EC:3.5.1.5]
MOC_1083  Gamma-glutamyltransferase [KO:K22602] [EC:3.5.1.126]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
mor00030  Pentose phosphate pathway
mor00220  Arginine biosynthesis
mor00250  Alanine, aspartate and glutamate metabolism
mor00260  Glycine, serine and threonine metabolism
mor00340  Histidine metabolism
mor00630  Glyoxylate and dicarboxylate metabolism
mor00730  Thiamine metabolism
mor00740  Riboflavin metabolism
mor00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

DBGET integrated database retrieval system