KEGG   PATHWAY: msem00630
Entry
msem00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Metabacillus sediminilitoris
Class
Metabolism; Carbohydrate metabolism
Pathway map
msem00630  Glyoxylate and dicarboxylate metabolism
msem00630

Module
msem_M00012  Glyoxylate cycle [PATH:msem00630]
msem_M00621  Glycine cleavage system [PATH:msem00630]
Other DBs
GO: 0046487 0043648
Organism
Metabacillus sediminilitoris [GN:msem]
Gene
GMB29_04525  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
GMB29_21025  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
GMB29_21090  acsA; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
GMB29_04520  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
GMB29_20850  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
GMB29_20860  citZ; citrate synthase [KO:K01659] [EC:2.3.3.5]
GMB29_13990  acnA; aconitate hydratase AcnA [KO:K27802] [EC:4.2.1.3 4.2.1.99]
GMB29_12295  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
GMB29_21845  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
GMB29_23545  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
GMB29_25780  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
GMB29_10065  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
GMB29_10450  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
GMB29_10610  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
GMB29_11890  enoyl-CoA hydratase [KO:K17865] [EC:4.2.1.55]
GMB29_20845  enoyl-CoA hydratase [KO:K17865] [EC:4.2.1.55]
GMB29_18925  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
GMB29_18920  methylmalonyl-CoA carboxyltransferase [KO:K01966] [EC:6.4.1.3 2.1.3.15]
GMB29_18970  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
GMB29_18975  hypothetical protein [KO:K01847] [EC:5.4.99.2]
GMB29_09560  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
GMB29_10100  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
GMB29_09565  4Fe-4S dicluster domain-containing protein [KO:K11473] [EC:1.1.99.14]
GMB29_10105  4Fe-4S dicluster domain-containing protein [KO:K11473] [EC:1.1.99.14]
GMB29_14055  catalase [KO:K03781] [EC:1.11.1.6]
GMB29_26420  catalase [KO:K03781] [EC:1.11.1.6]
GMB29_03960  catalase [KO:K03781] [EC:1.11.1.6]
GMB29_23020  D-glycerate dehydrogenase [KO:K00015] [EC:1.1.1.26]
GMB29_15250  bifunctional glyoxylate/hydroxypyruvate reductase B [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
GMB29_22505  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
GMB29_10340  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
GMB29_09955  gltB; glutamate synthase large subunit [KO:K00284] [EC:1.4.7.1]
GMB29_14015  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
GMB29_14355  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
GMB29_25615  aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme [KO:K00600] [EC:2.1.2.1]
GMB29_06040  aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme [KO:K00600] [EC:2.1.2.1]
GMB29_19250  aminomethyl-transferring glycine dehydrogenase subunit GcvPA [KO:K00282] [EC:1.4.4.2]
GMB29_06065  aminomethyl-transferring glycine dehydrogenase subunit GcvPA [KO:K00282] [EC:1.4.4.2]
GMB29_19245  aminotransferase class V-fold PLP-dependent enzyme [KO:K00283] [EC:1.4.4.2]
GMB29_06070  aminotransferase class V-fold PLP-dependent enzyme [KO:K00283] [EC:1.4.4.2]
GMB29_19255  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
GMB29_06055  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
GMB29_18230  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
GMB29_18995  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
GMB29_06090  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
GMB29_07590  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
GMB29_10955  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
GMB29_23155  gcvH; glycine cleavage system protein GcvH [KO:K02437]
GMB29_06060  gcvH; glycine cleavage system protein GcvH [KO:K02437]
GMB29_24470  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
GMB29_14315  glycerate kinase [KO:K00865] [EC:2.7.1.165]
GMB29_06255  ttdA; L(+)-tartrate dehydratase subunit alpha [KO:K03779] [EC:4.2.1.32]
GMB29_06260  ttdB; L(+)-tartrate dehydratase subunit beta [KO:K03780] [EC:4.2.1.32]
GMB29_06785  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
GMB29_13575  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
GMB29_22450  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
GMB29_08450  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
GMB29_26105  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
GMB29_06095  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
msem00010  Glycolysis / Gluconeogenesis
msem00020  Citrate cycle (TCA cycle)
msem00030  Pentose phosphate pathway
msem00053  Ascorbate and aldarate metabolism
msem00071  Fatty acid degradation
msem00230  Purine metabolism
msem00250  Alanine, aspartate and glutamate metabolism
msem00260  Glycine, serine and threonine metabolism
msem00620  Pyruvate metabolism
msem00710  Carbon fixation by Calvin cycle
msem00750  Vitamin B6 metabolism
msem00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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