KEGG   PATHWAY: mshj00630
Entry
mshj00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycobacterium shinjukuense
Class
Metabolism; Carbohydrate metabolism
Pathway map
mshj00630  Glyoxylate and dicarboxylate metabolism
mshj00630

Module
mshj_M00012  Glyoxylate cycle [PATH:mshj00630]
mshj_M00621  Glycine cleavage system [PATH:mshj00630]
mshj_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mshj00630]
Other DBs
GO: 0046487 0043648
Organism
Mycobacterium shinjukuense [GN:mshj]
Gene
MSHI_29700  icl; isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
MSHI_08940  aceA; isocitrate lyase 2 [KO:K01637] [EC:4.1.3.1 4.1.3.30]
MSHI_37630  acsA_2; acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
MSHI_09700  acsA_1; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
MSHI_13580  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
MSHI_04430  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
MSHI_00530  citA; putative citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
MSHI_00580  gltA2; citrate synthase [KO:K01647] [EC:2.3.3.1]
MSHI_03410  prpc; citrate synthase [KO:K01659] [EC:2.3.3.5]
MSHI_17340  acn; aconitate hydratase [KO:K27802] [EC:4.2.1.3 4.2.1.99]
MSHI_32340  fadA2; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSHI_38820  fadA6; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSHI_38940  hypothetical protein [KO:K00626] [EC:2.3.1.9]
MSHI_39170  ltp3; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSHI_40970  fadA; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSHI_00820  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSHI_02750  fadA3; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSHI_05450  fadA4; putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSHI_13360  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSHI_05440  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
MSHI_25310  accA3; acetyl-/propionyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
MSHI_25120  accD5; putative propionyl-CoA carboxylase beta chain 5 [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
MSHI_25130  hypothetical protein [KO:K27095]
MSHI_10150  accD6; putative propionyl-CoA carboxylase beta chain 6 [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
MSHI_17110  mutB; putative methylmalonyl-CoA mutase large subunit [KO:K01847] [EC:5.4.99.2]
MSHI_17120  mutA; putative methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
MSHI_04610  oxidoreductase [KO:K00104] [EC:1.1.99.14]
MSHI_09910  dehydrogenase [KO:K00104] [EC:1.1.99.14]
MSHI_37040  katA; catalase [KO:K03781] [EC:1.11.1.6]
MSHI_22180  glnA4; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
MSHI_10460  glnA2; putative glutamine synthetase 2 [KO:K01915] [EC:6.3.1.2]
MSHI_10490  glnA1; glutamine synthetase 1 [KO:K01915] [EC:6.3.1.2]
MSHI_13190  glnA3; glutamine synthetase GlnA [KO:K01915] [EC:6.3.1.2]
MSHI_36020  glyA2; serine hydroxymethyltransferase 2 [KO:K00600] [EC:2.1.2.1]
MSHI_02980  glyA1; serine hydroxymethyltransferase 1 [KO:K00600] [EC:2.1.2.1]
MSHI_36030  gcvP_2; glycine dehydrogenase (decarboxylating) [KO:K00281] [EC:1.4.4.2]
MSHI_13640  gcvP_1; putative glycine dehydrogenase (decarboxylating) [KO:K00281] [EC:1.4.4.2]
MSHI_10590  gcvT; aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
MSHI_29750  lpdC; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
MSHI_13690  gcvH; glycine cleavage system H protein [KO:K02437]
MSHI_10670  hypothetical protein [KO:K00865] [EC:2.7.1.165]
MSHI_04480  kgd; multifunctional 2-oxoglutarate metabolism enzyme [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
MSHI_07130  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
MSHI_36590  oxcA; oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mshj00010  Glycolysis / Gluconeogenesis
mshj00020  Citrate cycle (TCA cycle)
mshj00030  Pentose phosphate pathway
mshj00053  Ascorbate and aldarate metabolism
mshj00071  Fatty acid degradation
mshj00230  Purine metabolism
mshj00250  Alanine, aspartate and glutamate metabolism
mshj00260  Glycine, serine and threonine metabolism
mshj00620  Pyruvate metabolism
mshj00710  Carbon fixation by Calvin cycle
mshj00750  Vitamin B6 metabolism
mshj00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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